Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   GFB63_RS03410 Genome accession   NZ_CP045596
Coordinates   670527..671468 (-) Length   313 a.a.
NCBI ID   WP_014622005.1    Uniprot ID   A0A2X3UX10
Organism   Streptococcus thermophilus strain TK-P3A     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 665527..676468
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GFB63_RS03370 (GFB63_03465) - 665603..666796 (-) 1194 WP_084826168.1 acetate kinase -
  GFB63_RS03375 (GFB63_03470) comYH 666852..667808 (-) 957 WP_023909974.1 class I SAM-dependent methyltransferase Machinery gene
  GFB63_RS03380 (GFB63_03475) comGG 667853..668170 (-) 318 WP_023909975.1 competence type IV pilus minor pilin ComGG -
  GFB63_RS03385 (GFB63_03480) comYF 668148..668585 (-) 438 WP_084829135.1 competence type IV pilus minor pilin ComGF Machinery gene
  GFB63_RS03390 (GFB63_03485) comGE 668569..668862 (-) 294 WP_084829136.1 competence type IV pilus minor pilin ComGE -
  GFB63_RS03395 (GFB63_03490) comYD 668834..669262 (-) 429 WP_171815055.1 competence type IV pilus minor pilin ComGD Machinery gene
  GFB63_RS03400 (GFB63_03495) comYC 669222..669548 (-) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  GFB63_RS03405 (GFB63_03500) comYB 669545..670645 (-) 1101 WP_144239090.1 competence type IV pilus assembly protein ComGB Machinery gene
  GFB63_RS03410 (GFB63_03505) comYA 670527..671468 (-) 942 WP_014622005.1 competence type IV pilus ATPase ComGA Machinery gene
  GFB63_RS03415 (GFB63_03510) - 671549..671911 (-) 363 WP_023909982.1 DUF1033 family protein -
  GFB63_RS03420 (GFB63_03515) rpoC 672070..675708 (-) 3639 WP_111679735.1 DNA-directed RNA polymerase subunit beta' -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35421.62 Da        Isoelectric Point: 6.3927

>NTDB_id=395464 GFB63_RS03410 WP_014622005.1 670527..671468(-) (comYA) [Streptococcus thermophilus strain TK-P3A]
MVTEFAKEMIKNADSCGAQDIYVIPRQDNYELYMRVGQERRLIDVYRPDFMASLIGHFKFVAGMMVGEKRRSQLGACDYD
CGDGHLVSLRLSTVGDYRGLESLVIRILHSERRELVYWNQGIQPIKDALDYRGLYLFAGPVGSGKTTLMHELVQERFKGQ
QVISIEDPVEIKQDNVLQLQVNQVIDMTYDSLIKLSLRHRPDVLIIGEIRDKETARAVIRASLTGVTVLSTIHAKSIAGV
YERLLDLGVDKSELDNALQGIAYMRLIKGGGVIDFARENFQNHSSTNWNQQLEGLVKQGCLTERDIQGEKIKD

Nucleotide


Download         Length: 942 bp        

>NTDB_id=395464 GFB63_RS03410 WP_014622005.1 670527..671468(-) (comYA) [Streptococcus thermophilus strain TK-P3A]
ATGGTAACAGAATTTGCTAAGGAAATGATCAAAAATGCTGATAGTTGTGGGGCTCAAGACATCTATGTCATTCCACGTCA
GGATAATTATGAGCTCTATATGCGAGTCGGGCAAGAGAGGAGATTGATTGATGTATATCGGCCTGATTTCATGGCTAGTC
TTATTGGTCACTTTAAATTTGTGGCGGGAATGATGGTGGGTGAGAAGCGTAGGAGTCAACTGGGTGCATGTGACTATGAT
TGTGGTGACGGTCACTTGGTTTCTCTGCGTTTATCAACTGTTGGAGACTATCGAGGTTTGGAGAGCTTGGTTATCCGTAT
CCTACATTCCGAACGTCGAGAATTAGTGTATTGGAATCAAGGAATCCAGCCTATTAAGGATGCCTTGGATTATAGAGGAC
TGTATCTCTTTGCGGGTCCCGTAGGTTCTGGGAAGACCACACTTATGCATGAGTTGGTTCAGGAGCGTTTTAAGGGGCAG
CAGGTAATTTCGATTGAGGATCCTGTTGAAATCAAACAGGATAATGTCTTGCAACTCCAGGTTAATCAGGTGATTGATAT
GACCTATGATAGTTTGATTAAGCTATCTCTACGTCACCGTCCAGATGTTTTGATTATTGGGGAGATTCGGGATAAGGAGA
CTGCCCGGGCAGTTATTAGAGCTAGTCTAACAGGTGTAACTGTTCTTTCAACTATTCATGCTAAGAGTATTGCTGGCGTT
TACGAACGTCTCTTGGACCTTGGCGTAGATAAGTCTGAGTTGGATAATGCTCTACAAGGCATTGCCTACATGCGTTTGAT
CAAGGGGGGAGGTGTGATTGATTTTGCCAGAGAAAATTTCCAAAACCATTCGTCGACCAACTGGAATCAGCAGTTGGAAG
GTTTGGTTAAACAAGGATGTCTCACTGAGAGGGATATCCAAGGGGAAAAAATTAAAGATTAG

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(10-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2X3UX10

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

64.537

100

0.645
  comYA Streptococcus mutans UA140

64.537

100

0.645
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

64.952

99.361

0.645
  comGA/cglA/cilD Streptococcus pneumoniae D39

63.666

99.361

0.633
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

63.666

99.361

0.633
  comGA/cglA/cilD Streptococcus pneumoniae R6

63.666

99.361

0.633
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

63.666

99.361

0.633
  comYA Streptococcus gordonii str. Challis substr. CH1

62.939

100

0.629
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

61.859

99.681

0.617
  comGA Lactococcus lactis subsp. cremoris KW2

51.768

99.361

0.514
  comGA Latilactobacillus sakei subsp. sakei 23K

38.816

97.125

0.377

Multiple sequence alignment