Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   FDP16_RS10340 Genome accession   NZ_CP040798
Coordinates   2089448..2090389 (-) Length   313 a.a.
NCBI ID   WP_002896773.1    Uniprot ID   -
Organism   Streptococcus sanguinis strain CGMH058     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2084448..2095389
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FDP16_RS10305 (FDP16_10765) comYH 2085673..2086638 (-) 966 WP_124765830.1 class I SAM-dependent methyltransferase Machinery gene
  FDP16_RS10310 (FDP16_10770) comGG 2086720..2087112 (-) 393 WP_176799579.1 competence type IV pilus minor pilin ComGG -
  FDP16_RS10315 (FDP16_10775) comGF/cglF 2087093..2087530 (-) 438 WP_176799580.1 competence type IV pilus minor pilin ComGF Machinery gene
  FDP16_RS10320 (FDP16_10780) comGE/cglE 2087514..2087807 (-) 294 WP_176799581.1 competence type IV pilus minor pilin ComGE Machinery gene
  FDP16_RS10325 (FDP16_10785) comYD 2087773..2088207 (-) 435 WP_176799582.1 competence type IV pilus minor pilin ComGD Machinery gene
  FDP16_RS10330 (FDP16_10790) comYC 2088167..2088484 (-) 318 WP_002896769.1 competence type IV pilus major pilin ComGC Machinery gene
  FDP16_RS10335 (FDP16_10795) comYB 2088484..2089518 (-) 1035 WP_256254487.1 competence type IV pilus assembly protein ComGB Machinery gene
  FDP16_RS10340 (FDP16_10800) comYA 2089448..2090389 (-) 942 WP_002896773.1 competence type IV pilus ATPase ComGA Machinery gene
  FDP16_RS10345 (FDP16_10805) - 2090519..2090899 (-) 381 WP_176799584.1 DUF1033 family protein -
  FDP16_RS10350 (FDP16_10810) - 2091038..2092099 (-) 1062 WP_176799585.1 zinc-dependent alcohol dehydrogenase family protein -
  FDP16_RS10355 (FDP16_10815) - 2092269..2093375 (-) 1107 WP_176799586.1 glycosyl hydrolase family 8 -
  FDP16_RS10360 (FDP16_10820) - 2093384..2094694 (-) 1311 WP_176799587.1 glycosyltransferase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35897.16 Da        Isoelectric Point: 6.1771

>NTDB_id=367249 FDP16_RS10340 WP_002896773.1 2089448..2090389(-) (comYA) [Streptococcus sanguinis strain CGMH058]
MVQEIAKEMIRQARQEGAQDIYLIPKTTCYELYMRIGDERRFIKTYDFELLSAVISHFKFVAGMNVGEKRRSQLGSCDYD
CEEAKVSIRLSTVGDYRGFESLVIRLLHDEDRELRFWFEQLPELRKKIQARGLYLFSGPVGSGKTTLMYHLAQLKFSGQQ
VMSIEDPVEIKQEAMLQLQLNETIGMTYDSLIKLSLRHRPDLLIIGEIRDRETARAVVRASLTGATVFSTIHAKSVRGVY
ERLLELGVSEDELRMVLQGVCYQRLIGGGGVVDFVSQNYQEHEAAVWNQQIDQLFAEGHISAEQRQTEKIVYA

Nucleotide


Download         Length: 942 bp        

>NTDB_id=367249 FDP16_RS10340 WP_002896773.1 2089448..2090389(-) (comYA) [Streptococcus sanguinis strain CGMH058]
ATGGTTCAAGAAATTGCAAAAGAAATGATCAGGCAGGCTCGGCAAGAAGGGGCGCAGGATATTTACCTCATTCCTAAGAC
TACTTGCTATGAGCTTTATATGAGAATCGGTGATGAACGTCGCTTTATCAAGACTTATGATTTTGAGCTTTTGTCAGCGG
TTATCAGCCACTTTAAGTTTGTCGCAGGTATGAATGTTGGAGAGAAGCGCCGCAGTCAACTTGGGTCTTGCGATTATGAC
TGTGAGGAAGCCAAGGTTTCAATCCGGCTGTCGACAGTTGGGGATTACCGTGGTTTTGAAAGTCTGGTCATCCGACTCCT
GCATGATGAAGACAGGGAGCTACGCTTTTGGTTTGAGCAATTGCCGGAGTTGCGCAAGAAAATTCAGGCTCGCGGCCTCT
ATCTTTTCTCAGGCCCAGTCGGCAGTGGCAAGACGACCTTGATGTACCATTTGGCTCAGCTTAAATTTTCTGGTCAGCAG
GTTATGTCGATTGAAGATCCGGTTGAGATTAAGCAAGAGGCTATGCTGCAGCTGCAGCTGAACGAAACCATTGGCATGAC
TTATGATAGTCTGATTAAGCTGTCTCTGCGACATCGGCCGGATCTCTTGATTATCGGGGAAATCCGTGATCGAGAGACAG
CTAGAGCAGTGGTTCGGGCAAGTTTGACTGGAGCTACGGTCTTTTCGACGATTCATGCTAAGAGTGTTCGAGGTGTCTAT
GAGCGGCTTTTGGAATTGGGCGTCAGTGAGGATGAGCTAAGAATGGTGCTGCAAGGTGTTTGTTACCAGCGTTTAATTGG
GGGAGGAGGTGTCGTTGATTTTGTCAGTCAAAACTATCAAGAGCACGAAGCCGCAGTCTGGAATCAGCAGATTGATCAGC
TTTTTGCAGAAGGACATATCAGTGCTGAGCAAAGGCAGACCGAAAAAATTGTCTACGCCTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

80.645

99.042

0.799
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

75.08

100

0.751
  comGA/cglA/cilD Streptococcus pneumoniae D39

75.08

100

0.751
  comGA/cglA/cilD Streptococcus pneumoniae R6

75.08

100

0.751
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

75.08

100

0.751
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

74.76

100

0.748
  comYA Streptococcus mutans UA159

65.916

99.361

0.655
  comYA Streptococcus mutans UA140

65.916

99.361

0.655
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

64.839

99.042

0.642
  comGA Lactococcus lactis subsp. cremoris KW2

55.128

99.681

0.55
  comGA Latilactobacillus sakei subsp. sakei 23K

41.007

88.818

0.364

Multiple sequence alignment