Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   FDP16_RS10320 Genome accession   NZ_CP040798
Coordinates   2087514..2087807 (-) Length   97 a.a.
NCBI ID   WP_176799581.1    Uniprot ID   A0A7H8V3K4
Organism   Streptococcus sanguinis strain CGMH058     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2082514..2092807
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FDP16_RS10290 (FDP16_10750) - 2082794..2083432 (-) 639 WP_176799576.1 type II CAAX prenyl endopeptidase Rce1 family protein -
  FDP16_RS10295 (FDP16_10755) - 2083550..2084299 (-) 750 WP_176799577.1 CPBP family intramembrane glutamic endopeptidase -
  FDP16_RS10300 (FDP16_10760) - 2084446..2085636 (-) 1191 WP_176799578.1 acetate kinase -
  FDP16_RS10305 (FDP16_10765) comYH 2085673..2086638 (-) 966 WP_124765830.1 class I SAM-dependent methyltransferase Machinery gene
  FDP16_RS10310 (FDP16_10770) comGG 2086720..2087112 (-) 393 WP_176799579.1 competence type IV pilus minor pilin ComGG -
  FDP16_RS10315 (FDP16_10775) comGF/cglF 2087093..2087530 (-) 438 WP_176799580.1 competence type IV pilus minor pilin ComGF Machinery gene
  FDP16_RS10320 (FDP16_10780) comGE/cglE 2087514..2087807 (-) 294 WP_176799581.1 competence type IV pilus minor pilin ComGE Machinery gene
  FDP16_RS10325 (FDP16_10785) comYD 2087773..2088207 (-) 435 WP_176799582.1 competence type IV pilus minor pilin ComGD Machinery gene
  FDP16_RS10330 (FDP16_10790) comYC 2088167..2088484 (-) 318 WP_002896769.1 competence type IV pilus major pilin ComGC Machinery gene
  FDP16_RS10335 (FDP16_10795) comYB 2088484..2089518 (-) 1035 WP_256254487.1 competence type IV pilus assembly protein ComGB Machinery gene
  FDP16_RS10340 (FDP16_10800) comYA 2089448..2090389 (-) 942 WP_002896773.1 competence type IV pilus ATPase ComGA Machinery gene
  FDP16_RS10345 (FDP16_10805) - 2090519..2090899 (-) 381 WP_176799584.1 DUF1033 family protein -
  FDP16_RS10350 (FDP16_10810) - 2091038..2092099 (-) 1062 WP_176799585.1 zinc-dependent alcohol dehydrogenase family protein -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10941.93 Da        Isoelectric Point: 10.6606

>NTDB_id=367245 FDP16_RS10320 WP_176799581.1 2087514..2087807(-) (comGE/cglE) [Streptococcus sanguinis strain CGMH058]
MASLKRRQLQASILLEALVAMAVFAAIASLLLGQISRSRKEQQVLLQQEEVLRVARMALQTGQEELHINGITVRQLKTDK
QLLVYHEGEVVIRVQKP

Nucleotide


Download         Length: 294 bp        

>NTDB_id=367245 FDP16_RS10320 WP_176799581.1 2087514..2087807(-) (comGE/cglE) [Streptococcus sanguinis strain CGMH058]
ATGGCAAGTTTAAAAAGACGACAGCTTCAAGCTAGCATTCTGCTGGAAGCTCTGGTGGCCATGGCAGTTTTTGCGGCTAT
TGCCAGTTTGCTTTTGGGACAGATTAGCCGATCTCGTAAGGAGCAGCAGGTCCTTCTGCAGCAGGAAGAGGTGCTTCGGG
TAGCTCGTATGGCTCTGCAGACAGGGCAGGAAGAGCTTCATATCAACGGAATTACTGTACGTCAGCTTAAGACAGATAAG
CAGCTGCTGGTCTATCACGAAGGGGAGGTAGTCATCCGTGTCCAAAAACCTTAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7H8V3K4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae TIGR4

49.485

100

0.495
  comGE/cglE Streptococcus pneumoniae Rx1

49.485

100

0.495
  comGE/cglE Streptococcus pneumoniae D39

49.485

100

0.495
  comGE/cglE Streptococcus pneumoniae R6

49.485

100

0.495
  comGE/cglE Streptococcus mitis NCTC 12261

48.454

100

0.485
  comGE/cglE Streptococcus mitis SK321

48.454

100

0.485
  comYE Streptococcus mutans UA140

41.237

100

0.412
  comYE Streptococcus mutans UA159

41.237

100

0.412

Multiple sequence alignment