Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   EQH44_RS09625 Genome accession   NZ_CP035236
Coordinates   1890218..1890544 (-) Length   108 a.a.
NCBI ID   WP_000738630.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1902282     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1885218..1895544
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH44_RS09585 (EQH44_10120) rnpA 1885228..1885599 (-) 372 WP_000739246.1 ribonuclease P protein component -
  EQH44_RS10760 - 1885616..1885747 (-) 132 WP_000768904.1 hypothetical protein -
  EQH44_RS09590 (EQH44_10125) - 1885748..1886938 (-) 1191 WP_000167766.1 acetate kinase -
  EQH44_RS09595 (EQH44_10130) comYH 1886989..1887942 (-) 954 WP_000345133.1 class I SAM-dependent methyltransferase Machinery gene
  EQH44_RS09600 (EQH44_10135) - 1888003..1888604 (-) 602 Protein_1896 class I SAM-dependent methyltransferase -
  EQH44_RS09605 (EQH44_10140) comGG/cglG 1888741..1889154 (-) 414 WP_000265622.1 competence type IV pilus minor pilin ComGG Machinery gene
  EQH44_RS09610 (EQH44_10145) comGF/cglF 1889132..1889593 (-) 462 WP_000250534.1 competence type IV pilus minor pilin ComGF Machinery gene
  EQH44_RS09615 (EQH44_10150) comGE/cglE 1889556..1889858 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  EQH44_RS09620 (EQH44_10155) comGD/cglD 1889821..1890225 (-) 405 WP_000588024.1 competence type IV pilus minor pilin ComGD Machinery gene
  EQH44_RS09625 (EQH44_10160) comGC/cglC 1890218..1890544 (-) 327 WP_000738630.1 comG operon protein ComGC Machinery gene
  EQH44_RS09630 (EQH44_10165) comGB/cglB 1890546..1891562 (-) 1017 WP_078132591.1 competence type IV pilus assembly protein ComGB Machinery gene
  EQH44_RS09635 (EQH44_10170) comGA/cglA/cilD 1891510..1892451 (-) 942 WP_000249573.1 competence type IV pilus ATPase ComGA Machinery gene
  EQH44_RS09640 (EQH44_10175) - 1892527..1892892 (-) 366 WP_000286415.1 DUF1033 family protein -
  EQH44_RS09645 (EQH44_10180) - 1893043..1894101 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  EQH44_RS09650 (EQH44_10185) nagA 1894264..1895415 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12247.38 Da        Isoelectric Point: 9.8692

>NTDB_id=336776 EQH44_RS09625 WP_000738630.1 1890218..1890544(-) (comGC/cglC) [Streptococcus pneumoniae strain TVO_1902282]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLKD
DGRITEEQAKAYKEYHDKNGEANRKVND

Nucleotide


Download         Length: 327 bp        

>NTDB_id=336776 EQH44_RS09625 WP_000738630.1 1890218..1890544(-) (comGC/cglC) [Streptococcus pneumoniae strain TVO_1902282]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGGTGGAGATGTTGGTGGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTGGAAAAGAATGAAGATGCTAGCCTAAGCAAGTTAAAAGAC
GATGGGCGAATCACGGAAGAACAGGCTAAAGCTTATAAAGAATACCATGATAAAAATGGAGAAGCAAATCGTAAAGTCAA
TGATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(11-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus pneumoniae Rx1

96.296

100

0.963
  comGC/cglC Streptococcus pneumoniae D39

96.296

100

0.963
  comGC/cglC Streptococcus pneumoniae R6

96.296

100

0.963
  comGC/cglC Streptococcus pneumoniae TIGR4

95.37

100

0.954
  comGC/cglC Streptococcus mitis SK321

92.593

100

0.926
  comGC/cglC Streptococcus mitis NCTC 12261

94.898

90.741

0.861
  comYC Streptococcus gordonii str. Challis substr. CH1

67.961

95.37

0.648
  comYC Streptococcus mutans UA159

62.745

94.444

0.593
  comYC Streptococcus mutans UA140

62.745

94.444

0.593
  comGC Lactococcus lactis subsp. cremoris KW2

54.902

94.444

0.519
  comYC Streptococcus suis isolate S10

67.901

75

0.509
  comGC Staphylococcus aureus MW2

46.078

94.444

0.435
  comGC Staphylococcus aureus N315

46.078

94.444

0.435
  comGC Latilactobacillus sakei subsp. sakei 23K

45.349

79.63

0.361

Multiple sequence alignment