Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   EQH44_RS09615 Genome accession   NZ_CP035236
Coordinates   1889556..1889858 (-) Length   100 a.a.
NCBI ID   WP_000413382.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1902282     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1884556..1894858
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH44_RS09585 (EQH44_10120) rnpA 1885228..1885599 (-) 372 WP_000739246.1 ribonuclease P protein component -
  EQH44_RS10760 - 1885616..1885747 (-) 132 WP_000768904.1 hypothetical protein -
  EQH44_RS09590 (EQH44_10125) - 1885748..1886938 (-) 1191 WP_000167766.1 acetate kinase -
  EQH44_RS09595 (EQH44_10130) comYH 1886989..1887942 (-) 954 WP_000345133.1 class I SAM-dependent methyltransferase Machinery gene
  EQH44_RS09600 (EQH44_10135) - 1888003..1888604 (-) 602 Protein_1896 class I SAM-dependent methyltransferase -
  EQH44_RS09605 (EQH44_10140) comGG/cglG 1888741..1889154 (-) 414 WP_000265622.1 competence type IV pilus minor pilin ComGG Machinery gene
  EQH44_RS09610 (EQH44_10145) comGF/cglF 1889132..1889593 (-) 462 WP_000250534.1 competence type IV pilus minor pilin ComGF Machinery gene
  EQH44_RS09615 (EQH44_10150) comGE/cglE 1889556..1889858 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  EQH44_RS09620 (EQH44_10155) comGD/cglD 1889821..1890225 (-) 405 WP_000588024.1 competence type IV pilus minor pilin ComGD Machinery gene
  EQH44_RS09625 (EQH44_10160) comGC/cglC 1890218..1890544 (-) 327 WP_000738630.1 comG operon protein ComGC Machinery gene
  EQH44_RS09630 (EQH44_10165) comGB/cglB 1890546..1891562 (-) 1017 WP_078132591.1 competence type IV pilus assembly protein ComGB Machinery gene
  EQH44_RS09635 (EQH44_10170) comGA/cglA/cilD 1891510..1892451 (-) 942 WP_000249573.1 competence type IV pilus ATPase ComGA Machinery gene
  EQH44_RS09640 (EQH44_10175) - 1892527..1892892 (-) 366 WP_000286415.1 DUF1033 family protein -
  EQH44_RS09645 (EQH44_10180) - 1893043..1894101 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11108.08 Da        Isoelectric Point: 9.7273

>NTDB_id=336774 EQH44_RS09615 WP_000413382.1 1889556..1889858(-) (comGE/cglE) [Streptococcus pneumoniae strain TVO_1902282]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=336774 EQH44_RS09615 WP_000413382.1 1889556..1889858(-) (comGE/cglE) [Streptococcus pneumoniae strain TVO_1902282]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCCTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

100

100

1
  comGE/cglE Streptococcus pneumoniae D39

100

100

1
  comGE/cglE Streptococcus pneumoniae R6

100

100

1
  comGE/cglE Streptococcus pneumoniae TIGR4

100

100

1
  comGE/cglE Streptococcus mitis NCTC 12261

98

100

0.98
  comGE/cglE Streptococcus mitis SK321

98

100

0.98
  comYE Streptococcus mutans UA140

44.444

90

0.4
  comYE Streptococcus mutans UA159

44.444

90

0.4

Multiple sequence alignment