Detailed information NTG0336773

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: EQH44_RS09610
• Genome accession: NZ_CP035236
• Coordinates: 1889132..1889593 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250534.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_1902282
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1884132..1894593

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH44_RS09580 (EQH44_10115)	-	1884429..1885253 (-)	825	WP_000727904.1	membrane protein insertase YidC	-
EQH44_RS09585 (EQH44_10120)	rnpA	1885228..1885599 (-)	372	WP_000739246.1	ribonuclease P protein component	-
EQH44_RS10760	-	1885616..1885747 (-)	132	WP_000768904.1	hypothetical protein	-
EQH44_RS09590 (EQH44_10125)	-	1885748..1886938 (-)	1191	WP_000167766.1	acetate kinase	-
EQH44_RS09595 (EQH44_10130)	comYH	1886989..1887942 (-)	954	WP_000345133.1	class I SAM-dependent methyltransferase	Machinery gene
EQH44_RS09600 (EQH44_10135)	-	1888003..1888604 (-)	602	Protein_1896	class I SAM-dependent methyltransferase	-
EQH44_RS09605 (EQH44_10140)	comGG/cglG	1888741..1889154 (-)	414	WP_000265622.1	competence type IV pilus minor pilin ComGG	Machinery gene
EQH44_RS09610 (EQH44_10145)	comGF/cglF	1889132..1889593 (-)	462	WP_000250534.1	competence type IV pilus minor pilin ComGF	Machinery gene
EQH44_RS09615 (EQH44_10150)	comGE/cglE	1889556..1889858 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
EQH44_RS09620 (EQH44_10155)	comGD/cglD	1889821..1890225 (-)	405	WP_000588024.1	competence type IV pilus minor pilin ComGD	Machinery gene
EQH44_RS09625 (EQH44_10160)	comGC/cglC	1890218..1890544 (-)	327	WP_000738630.1	comG operon protein ComGC	Machinery gene
EQH44_RS09630 (EQH44_10165)	comGB/cglB	1890546..1891562 (-)	1017	WP_078132591.1	competence type IV pilus assembly protein ComGB	Machinery gene
EQH44_RS09635 (EQH44_10170)	comGA/cglA/cilD	1891510..1892451 (-)	942	WP_000249573.1	competence type IV pilus ATPase ComGA	Machinery gene
EQH44_RS09640 (EQH44_10175)	-	1892527..1892892 (-)	366	WP_000286415.1	DUF1033 family protein	-
EQH44_RS09645 (EQH44_10180)	-	1893043..1894101 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17972.67 Da
• Isoelectric Point: 9.6092

>NTDB_id=336773 EQH44_RS09610 WP_000250534.1 1889132..1889593(-) (comGF/cglF) [Streptococcus pneumoniae strain TVO_1902282]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLISEVRYQQQSEQKEWLLFVDQLEVELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTNARGRGYQPMVYGLKSVRITEDNQLVRFHFQFQKGLEREFIYRVEKEKS

Nucleotide

• Length: 462 bp

>NTDB_id=336773 EQH44_RS09610 WP_000250534.1 1889132..1889593(-) (comGF/cglF) [Streptococcus pneumoniae strain TVO_1902282]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTGCTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAGCTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAACTTGAGGTAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGATGATTTCCGTAAAACGAATGCTCG
TGGTCGAGGTTATCAGCCTATGGTTTATGGACTCAAATCTGTACGGATTACAGAGGACAATCAACTGGTTCGCTTTCATT
TCCAGTTCCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAAAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	100	100	1
comGF/cglF	Streptococcus pneumoniae D39	100	100	1
comGF/cglF	Streptococcus pneumoniae R6	100	100	1
comGF/cglF	Streptococcus pneumoniae TIGR4	100	100	1
comGF/cglF	Streptococcus mitis SK321	90.85	100	0.909
comGF/cglF	Streptococcus mitis NCTC 12261	89.542	100	0.895