Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   EQH45_RS09940 Genome accession   NZ_CP035235
Coordinates   1938450..1938776 (-) Length   108 a.a.
NCBI ID   WP_000738621.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1902276     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1933450..1943776
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH45_RS09900 (EQH45_10425) rnpA 1933468..1933839 (-) 372 WP_000739246.1 ribonuclease P protein component -
  EQH45_RS11110 - 1933856..1933987 (-) 132 WP_000768904.1 hypothetical protein -
  EQH45_RS09905 (EQH45_10430) - 1933988..1935178 (-) 1191 WP_000167768.1 acetate kinase -
  EQH45_RS09910 (EQH45_10435) comYH 1935229..1936182 (-) 954 WP_000345086.1 class I SAM-dependent methyltransferase Machinery gene
  EQH45_RS09915 (EQH45_10440) - 1936243..1936837 (-) 595 Protein_1955 class I SAM-dependent methyltransferase -
  EQH45_RS09920 (EQH45_10445) comGG/cglG 1936940..1937386 (-) 447 WP_001811371.1 competence type IV pilus minor pilin ComGG Machinery gene
  EQH45_RS09925 (EQH45_10450) comGF/cglF 1937364..1937825 (-) 462 WP_000250523.1 competence type IV pilus minor pilin ComGF Machinery gene
  EQH45_RS09930 (EQH45_10455) comGE/cglE 1937788..1938090 (-) 303 WP_000413380.1 competence type IV pilus minor pilin ComGE Machinery gene
  EQH45_RS09935 (EQH45_10460) comGD/cglD 1938053..1938457 (-) 405 WP_000588023.1 competence type IV pilus minor pilin ComGD Machinery gene
  EQH45_RS09940 (EQH45_10465) comGC/cglC 1938450..1938776 (-) 327 WP_000738621.1 comG operon protein ComGC Machinery gene
  EQH45_RS09945 (EQH45_10470) comGB/cglB 1938778..1939794 (-) 1017 WP_074017570.1 competence type IV pilus assembly protein ComGB Machinery gene
  EQH45_RS09950 (EQH45_10475) comGA/cglA/cilD 1939742..1940683 (-) 942 WP_000249568.1 competence type IV pilus ATPase ComGA Machinery gene
  EQH45_RS09955 (EQH45_10480) - 1940759..1941124 (-) 366 WP_000286415.1 DUF1033 family protein -
  EQH45_RS09960 (EQH45_10485) - 1941275..1942333 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  EQH45_RS09965 (EQH45_10490) nagA 1942496..1943647 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12240.44 Da        Isoelectric Point: 10.1432

>NTDB_id=336701 EQH45_RS09940 WP_000738621.1 1938450..1938776(-) (comGC/cglC) [Streptococcus pneumoniae strain TVO_1902276]
MKKMMTFLKKAKVKAFTLIEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDASLRKLQA
DGRITEEQVKAYNEYYTKNGGANRKVND

Nucleotide


Download         Length: 327 bp        

>NTDB_id=336701 EQH45_RS09940 WP_000738621.1 1938450..1938776(-) (comGC/cglC) [Streptococcus pneumoniae strain TVO_1902276]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGATTGAGATGTTGGTGGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTAGAAAAGAATGAAGATGCTAGCCTAAGAAAGTTACAAGCA
GATGGGCGCATCACGGAAGAACAGGTTAAAGCTTATAATGAATACTATACTAAAAATGGAGGGGCAAATCGTAAAGTCAA
TGATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(11-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus pneumoniae Rx1

95.37

100

0.954
  comGC/cglC Streptococcus pneumoniae D39

95.37

100

0.954
  comGC/cglC Streptococcus pneumoniae R6

95.37

100

0.954
  comGC/cglC Streptococcus pneumoniae TIGR4

95.37

100

0.954
  comGC/cglC Streptococcus mitis SK321

94.444

100

0.944
  comGC/cglC Streptococcus mitis NCTC 12261

91.837

90.741

0.833
  comYC Streptococcus gordonii str. Challis substr. CH1

66.019

95.37

0.63
  comYC Streptococcus mutans UA159

62.745

94.444

0.593
  comYC Streptococcus mutans UA140

62.745

94.444

0.593
  comGC Lactococcus lactis subsp. cremoris KW2

55.882

94.444

0.528
  comYC Streptococcus suis isolate S10

67.901

75

0.509
  comGC Staphylococcus aureus MW2

51.163

79.63

0.407
  comGC Staphylococcus aureus N315

51.163

79.63

0.407
  comGC Latilactobacillus sakei subsp. sakei 23K

45.349

79.63

0.361

Multiple sequence alignment