Detailed information NTG0033454

Bioinformatically predicted

Overview

• Name: comX/sigX/comX2/sigX2
• Type: Regulator
• Locus tag: SZO_RS01630
• Genome accession: NC_012470
• Coordinates: 343621..344106 (+)
• Length: 161 a.a.
• NCBI ID: WP_012677392.1
• Uniprot ID: A0A380JSU6
• Organism: Streptococcus equi subsp. zooepidemicus
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 338621..349106

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SZO_RS01630 (SZO_02830)	comX/sigX/comX2/sigX2	343621..344106 (+)	486	WP_012677392.1	hypothetical protein	Regulator
SZO_RS01635 (SZO_02840)	-	344244..344771 (+)	528	WP_012677393.1	YqeG family HAD IIIA-type phosphatase	-
SZO_RS01640 (SZO_02850)	yqeH	344771..345889 (+)	1119	WP_012677394.1	ribosome biogenesis GTPase YqeH	-
SZO_RS01645 (SZO_02860)	yhbY	345916..346224 (+)	309	WP_012516273.1	ribosome assembly RNA-binding protein YhbY	-
SZO_RS01650 (SZO_02870)	-	346308..346940 (+)	633	WP_012677395.1	nicotinate-nucleotide adenylyltransferase	-
SZO_RS01655 (SZO_02880)	yqeK	346937..347530 (+)	594	WP_012677396.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
SZO_RS01660 (SZO_02890)	rsfS	347532..347885 (+)	354	WP_012677397.1	ribosome silencing factor	-
SZO_RS01665 (SZO_02900)	-	347997..348758 (+)	762	WP_323126106.1	class I SAM-dependent methyltransferase	-

Sequence

Protein

• Length: 161 a.a.
• Molecular weight: 19371.39 Da
• Isoelectric Point: 7.3119

>NTDB_id=33454 SZO_RS01630 WP_012677392.1 343621..344106(+) (comX/sigX/comX2/sigX2) [Streptococcus equi subsp. zooepidemicus]
MSDDLVRLFDKIKPIIMKLRRHYYIQLWELDDWLQEGRLILYRLLVTYPELIEDEEKLYRYFKTKFSSYLKDVLRQQESQ
KRRFHKMAYEEIGAVGHAIPAGGLGVDDYVAYQLIVKEVEEQLTESELLQFRALIRGERFEGRRALLRKIGPYFQDFTGE
K

Nucleotide

• Length: 486 bp

>NTDB_id=33454 SZO_RS01630 WP_012677392.1 343621..344106(+) (comX/sigX/comX2/sigX2) [Streptococcus equi subsp. zooepidemicus]
ATGAGTGATGATTTAGTGAGGTTGTTTGATAAGATCAAGCCTATTATTATGAAGCTAAGACGGCATTATTATATTCAGCT
GTGGGAGCTAGATGATTGGTTACAGGAGGGGCGGTTGATCTTGTATCGGTTATTGGTCACTTATCCAGAATTGATAGAGG
ATGAGGAGAAGCTGTACCGTTATTTTAAGACCAAGTTTTCCTCTTATTTGAAGGACGTGTTGCGGCAGCAGGAGAGTCAG
AAGCGTCGGTTTCATAAGATGGCTTATGAGGAGATTGGGGCGGTAGGGCATGCGATACCAGCAGGTGGCTTGGGAGTAGA
TGATTATGTGGCTTATCAGTTGATTGTGAAGGAGGTTGAGGAGCAATTGACAGAGAGCGAGCTGTTACAGTTTAGGGCTT
TGATCAGGGGAGAGCGGTTTGAGGGGAGACGGGCCTTGCTTCGCAAGATAGGACCTTACTTTCAGGACTTTACTGGTGAG
AAATAA

Domains

No domain identified.

3D structure

• AlphaFold DB: A0A380JSU6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	68.75	99.379	0.683
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	68.75	99.379	0.683
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	68.75	99.379	0.683
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	68.75	99.379	0.683
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	68.75	99.379	0.683
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	68.75	99.379	0.683
comX/sigX	Streptococcus infantarius subsp. infantarius ATCC BAA-102	48.387	96.273	0.466
comX/sigX	Streptococcus mutans UA159	46.497	97.516	0.453
comX	Streptococcus sobrinus strain NIDR 6715-7	45.752	95.031	0.435
comX/sigX/comX2/sigX2	Streptococcus mitis SK321	40.667	93.168	0.379
comX	Streptococcus thermophilus LMD-9	39.216	95.031	0.373
comX	Streptococcus thermophilus LMG 18311	39.216	95.031	0.373
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	39.735	93.789	0.373
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	39.735	93.789	0.373
comX/sigX/comX1/sigX1	Streptococcus mitis SK321	39.333	93.168	0.366
comX/comX2	Streptococcus pneumoniae Rx1	38.411	93.789	0.36
comX/comX1	Streptococcus pneumoniae Rx1	38.411	93.789	0.36
comX/comX2	Streptococcus pneumoniae D39	38.411	93.789	0.36
comX/comX1	Streptococcus pneumoniae D39	38.411	93.789	0.36
comX/comX2	Streptococcus pneumoniae R6	38.411	93.789	0.36
comX/comX1	Streptococcus pneumoniae R6	38.411	93.789	0.36
comX/comX1	Streptococcus pneumoniae TIGR4	38.411	93.789	0.36
comX/comX2	Streptococcus pneumoniae TIGR4	38.411	93.789	0.36
comX/sigX/comX2/sigX2	Streptococcus mitis NCTC 12261	38.667	93.168	0.36