Detailed information NTG0331381

Bioinformatically predicted

Overview

• Name: comGC/cglC
• Type: Machinery gene
• Locus tag: EJF26_RS08430
• Genome accession: NZ_CP034442
• Coordinates: 1651283..1651606 (+)
• Length: 107 a.a.
• NCBI ID: WP_000735797.1
• Uniprot ID: A0A139PI93
• Organism: Streptococcus oralis subsp. dentisani strain F0392
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1646283..1656606

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EJF26_RS08410	nagA	1647647..1648798 (+)	1152	WP_001134436.1	N-acetylglucosamine-6-phosphate deacetylase	-
EJF26_RS08415	-	1648947..1649312 (+)	366	WP_000286403.1	DUF1033 family protein	-
EJF26_RS08420	comGA/cglA/cilD	1649376..1650317 (+)	942	WP_000249589.1	competence type IV pilus ATPase ComGA	Machinery gene
EJF26_RS08425	comGB/cglB	1650265..1651281 (+)	1017	WP_000355376.1	competence type IV pilus assembly protein ComGB	Machinery gene
EJF26_RS08430	comGC/cglC	1651283..1651606 (+)	324	WP_000735797.1	competence type IV pilus major pilin ComGC	Machinery gene
EJF26_RS08435	comGD/cglD	1651569..1652003 (+)	435	WP_001180063.1	competence type IV pilus minor pilin ComGD	Machinery gene
EJF26_RS08440	comGE/cglE	1651966..1652268 (+)	303	WP_000413366.1	competence type IV pilus minor pilin ComGE	Machinery gene
EJF26_RS08445	comGF/cglF	1652231..1652692 (+)	462	WP_000250704.1	competence type IV pilus minor pilin ComGF	Machinery gene
EJF26_RS08450	comGG/cglG	1652670..1653083 (+)	414	WP_000265655.1	competence type IV pilus minor pilin ComGG	Machinery gene
EJF26_RS08455	-	1653116..1653706 (+)	591	WP_000679780.1	class I SAM-dependent methyltransferase	-
EJF26_RS08460	comYH	1653764..1654717 (+)	954	WP_000345148.1	class I SAM-dependent methyltransferase	Machinery gene
EJF26_RS08465	-	1654767..1655957 (+)	1191	WP_000167801.1	acetate kinase	-
EJF26_RS08470	rnpA	1656117..1656488 (+)	372	WP_000748123.1	ribonuclease P protein component	-

Sequence

Protein

• Length: 107 a.a.
• Molecular weight: 11820.94 Da
• Isoelectric Point: 10.1889

>NTDB_id=331381 EJF26_RS08430 WP_000735797.1 1651283..1651606(+) (comGC/cglC) [Streptococcus oralis subsp. dentisani strain F0392]
MKKLMTNLKKAKAKAFTLVEMLVVLLIISVLLLLFVPNLTKQKDAVNDKGKAAVVKVVESQAELYSLDKNEDASLSKLQA
DGRITAEQAKAYKEYHAKQKTSQTVAD

Nucleotide

• Length: 324 bp

>NTDB_id=331381 EJF26_RS08430 WP_000735797.1 1651283..1651606(+) (comGC/cglC) [Streptococcus oralis subsp. dentisani strain F0392]
ATGAAAAAACTTATGACAAATTTGAAAAAAGCCAAGGCGAAAGCCTTTACTCTCGTGGAAATGTTGGTGGTCCTTTTAAT
CATTAGCGTACTTCTCTTGCTCTTTGTGCCTAATTTGACCAAACAAAAGGATGCAGTGAATGACAAAGGAAAAGCTGCTG
TTGTTAAGGTGGTGGAAAGTCAGGCAGAACTCTATAGTCTGGACAAGAATGAAGATGCTAGCCTAAGCAAATTACAGGCA
GACGGTCGCATCACAGCAGAGCAAGCCAAGGCTTATAAAGAATACCATGCAAAACAAAAAACAAGTCAAACTGTTGCGGA
TTAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (11-34)

3D structure

• AlphaFold DB: A0A139PI93

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGC/cglC	Streptococcus mitis NCTC 12261	94.393	100	0.944
comGC/cglC	Streptococcus mitis SK321	92.857	91.589	0.85
comGC/cglC	Streptococcus pneumoniae Rx1	90.816	91.589	0.832
comGC/cglC	Streptococcus pneumoniae D39	90.816	91.589	0.832
comGC/cglC	Streptococcus pneumoniae R6	90.816	91.589	0.832
comGC/cglC	Streptococcus pneumoniae TIGR4	89.796	91.589	0.822
comYC	Streptococcus gordonii str. Challis substr. CH1	66.667	98.131	0.654
comYC	Streptococcus mutans UA140	67.01	90.654	0.607
comYC	Streptococcus mutans UA159	67.01	90.654	0.607
comYC	Streptococcus suis isolate S10	65.909	82.243	0.542
comGC	Lactococcus lactis subsp. cremoris KW2	55.446	94.393	0.523
comGC	Latilactobacillus sakei subsp. sakei 23K	43.478	85.981	0.374