Detailed information NTG0031399

Bioinformatically predicted

Overview

• Name: comX/sigX/comX2/sigX2
• Type: Regulator
• Locus tag: SEZ_RS08440
• Genome accession: NC_011134
• Coordinates: 1781484..1781963 (-)
• Length: 159 a.a.
• NCBI ID: WP_012516276.1
• Uniprot ID: B4U4V3
• Organism: Streptococcus equi subsp. zooepidemicus MGCS10565
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1776484..1786963

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SEZ_RS08415 (Sez_1726)	-	1776914..1777474 (-)	561	WP_012516308.1	TIGR01440 family protein	-
SEZ_RS08420 (Sez_1727)	-	1777487..1777960 (-)	474	WP_012516309.1	ECF transporter S component	-
SEZ_RS08425 (Sez_1728)	-	1777966..1778715 (-)	750	WP_012516310.1	bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase	-
SEZ_RS08430 (Sez_1729)	truA	1778705..1779454 (-)	750	WP_012516311.1	tRNA pseudouridine(38-40) synthase TruA	-
SEZ_RS08435 (Sez_1731)	-	1779641..1781005 (+)	1365	WP_012516313.1	aspartate kinase	-
SEZ_RS08440 (Sez_1733)	comX/sigX/comX2/sigX2	1781484..1781963 (-)	480	WP_012516276.1	hypothetical protein	Regulator

Sequence

Protein

• Length: 159 a.a.
• Molecular weight: 19128.13 Da
• Isoelectric Point: 7.3117

>NTDB_id=31399 SEZ_RS08440 WP_012516276.1 1781484..1781963(-) (comX/sigX/comX2/sigX2) [Streptococcus equi subsp. zooepidemicus MGCS10565]
MTDDLVRLFDKIKPIIMKLRRHYYIQLWELDDWLQEGRLILYRLLVTYPELIEDEEKLYRYFKTKFSSYLKDVLRQQESQ
KRRFHKMAYEEIGAVGHAIPAGGLGVDDYVAYQLIVKEVEEQLTESELLQFRALIRGERFEGRRALLRKIGPYFQDFTG

Nucleotide

• Length: 480 bp

>NTDB_id=31399 SEZ_RS08440 WP_012516276.1 1781484..1781963(-) (comX/sigX/comX2/sigX2) [Streptococcus equi subsp. zooepidemicus MGCS10565]
ATGACTGATGATTTAGTGAGGTTATTTGATAAGATCAAGCCTATTATTATGAAGCTAAGACGGCATTATTATATTCAGCT
GTGGGAGCTGGATGATTGGTTACAGGAGGGACGGTTGATCTTGTATCGGTTGTTGGTTACTTATCCAGAATTGATAGAGG
ATGAGGAGAAGCTGTACCGTTACTTTAAGACCAAGTTTTCCTCTTATTTGAAGGACGTGTTGCGGCAGCAGGAGAGTCAG
AAGCGTCGGTTTCATAAGATGGCTTATGAGGAGATTGGGGCGGTAGGCCATGCGATACCAGCAGGTGGCTTGGGAGTAGA
TGATTATGTGGCTTATCAGTTGATTGTGAAGGAGGTTGAGGAGCAATTGACAGAGAGCGAGCTGTTACAGTTTAGGGCTT
TGATCAGGGGAGAGCGGTTTGAGGGGAGACGGGCCTTGCTTCGCAAGATAGGACCTTACTTTCAGGATTTTACTGGCTAG

Domains

No domain identified.

3D structure

• AlphaFold DB: B4U4V3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	68.987	99.371	0.686
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	68.987	99.371	0.686
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	68.987	99.371	0.686
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	68.987	99.371	0.686
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	68.987	99.371	0.686
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	68.987	99.371	0.686
comX/sigX	Streptococcus infantarius subsp. infantarius ATCC BAA-102	48.387	97.484	0.472
comX/sigX	Streptococcus mutans UA159	46.497	98.742	0.459
comX	Streptococcus sobrinus strain NIDR 6715-7	45.752	96.226	0.44
comX/sigX/comX2/sigX2	Streptococcus mitis SK321	40.667	94.34	0.384
comX	Streptococcus thermophilus LMD-9	39.216	96.226	0.377
comX	Streptococcus thermophilus LMG 18311	39.216	96.226	0.377
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	39.735	94.969	0.377
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	39.735	94.969	0.377
comX/sigX/comX1/sigX1	Streptococcus mitis SK321	39.333	94.34	0.371
comX/comX2	Streptococcus pneumoniae Rx1	38.411	94.969	0.365
comX/comX1	Streptococcus pneumoniae Rx1	38.411	94.969	0.365
comX/comX2	Streptococcus pneumoniae D39	38.411	94.969	0.365
comX/comX2	Streptococcus pneumoniae R6	38.411	94.969	0.365
comX/comX1	Streptococcus pneumoniae R6	38.411	94.969	0.365
comX/comX1	Streptococcus pneumoniae D39	38.411	94.969	0.365
comX/comX2	Streptococcus pneumoniae TIGR4	38.411	94.969	0.365
comX/comX1	Streptococcus pneumoniae TIGR4	38.411	94.969	0.365
comX/sigX/comX2/sigX2	Streptococcus mitis NCTC 12261	38.667	94.34	0.365