Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   CH556_RS03595 Genome accession   NZ_CP031692
Coordinates   704919..706139 (+) Length   406 a.a.
NCBI ID   WP_116945234.1    Uniprot ID   -
Organism   Haemophilus influenzae strain P595-8370     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 699919..711139
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CH556_RS03575 (CH556_03575) corC 700881..701780 (-) 900 WP_005648977.1 CNNM family magnesium/cobalt transport protein CorC -
  CH556_RS03580 (CH556_03580) ampD 702414..702968 (-) 555 WP_116945237.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  CH556_RS03585 (CH556_03585) pilA 703082..703531 (+) 450 WP_116945236.1 prepilin peptidase-dependent pilin Machinery gene
  CH556_RS03590 (CH556_03590) pilB 703528..704922 (+) 1395 WP_116945235.1 GspE/PulE family protein Machinery gene
  CH556_RS03595 (CH556_03595) pilC 704919..706139 (+) 1221 WP_116945234.1 type II secretion system F family protein Machinery gene
  CH556_RS03600 (CH556_03600) pilD 706136..706828 (+) 693 WP_116945233.1 A24 family peptidase Machinery gene
  CH556_RS03605 (CH556_03605) rho 706882..708144 (-) 1263 WP_005648966.1 transcription termination factor Rho -
  CH556_RS03610 (CH556_03610) metJ 708392..708709 (+) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  CH556_RS03615 (CH556_03615) cueR 708723..709109 (-) 387 WP_005648963.1 Cu(I)-responsive transcriptional regulator -
  CH556_RS03620 (CH556_03620) - 709186..709392 (+) 207 WP_005648955.1 heavy-metal-associated domain-containing protein -
  CH556_RS03625 (CH556_03625) - 709478..709684 (+) 207 WP_005686717.1 heavy-metal-associated domain-containing protein -
  CH556_RS03630 (CH556_03630) - 709769..709975 (+) 207 WP_005686717.1 heavy-metal-associated domain-containing protein -
  CH556_RS03635 (CH556_03635) - 710060..710266 (+) 207 WP_005689491.1 heavy-metal-associated domain-containing protein -

Sequence

Protein


Download         Length: 406 a.a.        Molecular weight: 46227.49 Da        Isoelectric Point: 9.8092

>NTDB_id=310276 CH556_RS03595 WP_116945234.1 704919..706139(+) (pilC) [Haemophilus influenzae strain P595-8370]
MTKKLFYYQGSNALNQKQKGSIIADTKQQAHFQLISCGLTHIKLQQNWQFGTKPKNSEISELLNQLATLLQSAIPLKNSL
QILQQNCTQIMLNEWLERLLQSIEAGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLAVVCKKIATHRSQSLALQRKLQK
IMLYPSMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQNIGILLFFAFSFFLFYYFYLKRQTWF
HQKKNQLISITPIFGTIQKLSRLVNFSQSLKIMLQAGVPLNQALDSFLPRTQTWQTKKTLVNDMVLDKEVRSILQWVSQG
YAFSNSVSSDLFPMEAQQMLQIGEQSGKLALMLEHIADNYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFN
MGSVIQ

Nucleotide


Download         Length: 1221 bp        

>NTDB_id=310276 CH556_RS03595 WP_116945234.1 704919..706139(+) (pilC) [Haemophilus influenzae strain P595-8370]
ATGACTAAAAAACTCTTTTATTATCAAGGTAGTAACGCATTAAATCAGAAACAAAAAGGCTCAATTATTGCGGATACGAA
ACAACAAGCACACTTTCAATTAATAAGCTGCGGGCTTACTCACATCAAATTACAACAAAACTGGCAATTTGGGACAAAGC
CCAAAAATTCAGAAATCAGTGAATTACTCAATCAATTAGCCACGTTGCTACAGTCCGCTATTCCGTTAAAAAACAGCCTG
CAAATTTTGCAACAAAATTGCACTCAAATTATGCTCAATGAATGGCTTGAACGACTGCTTCAATCTATTGAAGCTGGTTT
AGCATTTTCACAAGCCATTGAACAACAAGGGAAATATCTCACACAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CAGGCAAACTAGCCGTAGTTTGTAAAAAAATAGCCACACATCGCAGCCAATCTTTAGCATTACAACGTAAATTACAGAAA
ATCATGTTGTACCCCTCAATGGTGTTAGGAATTTCTCTATTATTGACACTCGCATTACTGCTTTTTATCGTGCCTCAATT
TGCTGAAATGTACAGTGGCAATAATGCTGAGTTACCGACAATCACCGCAATATTGCTCTCTATATCCAATTTTCTTAAGC
AAAATATTGGCATTTTGCTATTTTTCGCTTTTAGTTTTTTTCTATTTTATTACTTCTATCTAAAACGCCAGACTTGGTTT
CATCAAAAGAAAAATCAACTTATTTCTATCACGCCTATTTTTGGCACAATTCAAAAGCTTTCACGTTTAGTGAACTTTAG
TCAAAGTTTAAAAATTATGTTGCAGGCTGGCGTACCGCTTAATCAGGCACTAGACAGTTTTCTTCCTCGCACACAAACTT
GGCAAACCAAGAAAACGCTTGTAAACGATATGGTATTAGATAAAGAAGTGCGGTCAATTTTGCAATGGGTTTCTCAAGGC
TATGCGTTTTCTAATAGCGTAAGTAGCGATCTTTTCCCGATGGAAGCACAACAAATGCTACAAATTGGCGAGCAAAGCGG
AAAACTCGCTTTGATGCTAGAGCATATCGCGGATAATTACCAAGAAAAACTTAATCATCAAATTGACTTACTCTCACAAA
TGCTAGAACCATTAATGATGGTAATCATCGGAAGCCTGATTGGAATTATTATGATGGGAATGTATTTACCTATCTTTAAT
ATGGGTTCTGTTATTCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(63-185)

Type II secretion system (T2SS), protein F (T2SSF)

(266-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae 86-028NP

97.783

100

0.978
  pilC Haemophilus influenzae Rd KW20

97.044

100

0.97
  pilC Glaesserella parasuis strain SC1401

38.903

98.768

0.384

Multiple sequence alignment