Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGH   Type   Machinery gene
Locus tag   ES276_RS09710 Genome accession   NZ_CP038252
Coordinates   1926384..1927337 (-) Length   317 a.a.
NCBI ID   WP_000345135.1    Uniprot ID   A0A0H2URU7
Organism   Streptococcus pneumoniae strain TVO_1901936     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1921384..1932337
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ES276_RS09685 (ES276_10300) - 1922145..1922768 (-) 624 WP_000932644.1 hypothetical protein -
  ES276_RS09690 (ES276_10305) jag 1922819..1923805 (-) 987 WP_000260012.1 RNA-binding cell elongation regulator Jag/EloR -
  ES276_RS09695 (ES276_10310) - 1923824..1924648 (-) 825 WP_000727904.1 membrane protein insertase YidC -
  ES276_RS09700 (ES276_10315) rnpA 1924623..1924994 (-) 372 WP_000739253.1 ribonuclease P protein component -
  ES276_RS10870 - 1925011..1925142 (-) 132 WP_000768904.1 hypothetical protein -
  ES276_RS09705 (ES276_10320) - 1925143..1926333 (-) 1191 WP_000167757.1 acetate kinase -
  ES276_RS09710 (ES276_10325) comGH 1926384..1927337 (-) 954 WP_000345135.1 class I SAM-dependent methyltransferase Machinery gene
  ES276_RS09715 (ES276_10330) - 1927398..1927992 (-) 595 Protein_1916 class I SAM-dependent methyltransferase -
  ES276_RS09720 (ES276_10335) comGG/cglG 1928129..1928542 (-) 414 WP_000265622.1 competence type IV pilus minor pilin ComGG Machinery gene
  ES276_RS09725 (ES276_10340) comGF/cglF 1928520..1928981 (-) 462 WP_000250534.1 competence type IV pilus minor pilin ComGF Machinery gene
  ES276_RS09730 (ES276_10345) comGE/cglE 1928944..1929246 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  ES276_RS09735 (ES276_10350) comGD/cglD 1929209..1929613 (-) 405 WP_000588028.1 competence type IV pilus minor pilin ComGD Machinery gene
  ES276_RS09740 (ES276_10355) comGC/cglC 1929606..1929932 (-) 327 WP_000738627.1 comG operon protein ComGC Machinery gene
  ES276_RS09745 (ES276_10360) comGB/cglB 1929934..1930950 (-) 1017 WP_074196785.1 competence type IV pilus assembly protein ComGB Machinery gene
  ES276_RS09750 (ES276_10365) comGA/cglA/cilD 1930898..1931839 (-) 942 WP_000249564.1 competence type IV pilus ATPase ComGA Machinery gene
  ES276_RS09755 (ES276_10370) - 1931915..1932280 (-) 366 WP_000286415.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35756.99 Da        Isoelectric Point: 4.2748

>NTDB_id=310269 ES276_RS09710 WP_000345135.1 1926384..1927337(-) (comGH) [Streptococcus pneumoniae strain TVO_1901936]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELNQVKENNQTLKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFKEEEITILEMGSGMGILGAIFLTSLTKKVDYLGMEVDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGLKYLKSDGYAIFLAPSDLLTSPQ
SDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFILQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=310269 ES276_RS09710 WP_000345135.1 1926384..1927337(-) (comGH) [Streptococcus pneumoniae strain TVO_1901936]
ATGGATTTTGAAAAAATTGAACAAGCTTATACCTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAATAGCATCTATCTGGATGGTGAAACTGAGCTAAACCAGGTCAAGGAGAACAATC
AAACCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACACCGGATGCTATTGCTTTGCTTTTGGTGTTTATTGTGGAAGAGTTGTTTAA
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTCTAGGCGCTATTTTCTTGACCTCGCTTACTAAAA
AGGTGGATTACTTGGGAATGGAAGTGGATGATTTGCTGATTGATCTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGCCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTCGG
CTATTATCCTGATGATGCCGTTGCGTCGCGCCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCCCATCACTTGCTCA
TGGAACAAGGGCTTAAGTACCTCAAGTCAGACGGATACGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGTCCTCAA
AGTGATTTGTTAAAAGAATGGCTGAAAGAAGAGGCGAGTCTGGTTGCTATGATTAGTCTGCCTGAAAATCTCTTTGCTAA
TGCCAAACAATCTAAGACTATTTTTATCTTACAGAAGAAAAATGAAATAGCAGTAGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterProScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2URU7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGH Streptococcus mutans UA140

54.633

98.738

0.539
  comGH Streptococcus mutans UA159

54.313

98.738

0.536

Multiple sequence alignment