Detailed information NTG0310270

Bioinformatically predicted

Overview

• Name: comGG/cglG
• Type: Machinery gene
• Locus tag: ES276_RS09720
• Genome accession: NZ_CP038252
• Coordinates: 1928129..1928542 (-)
• Length: 137 a.a.
• NCBI ID: WP_000265622.1
• Uniprot ID: A0A0H2URX9
• Organism: Streptococcus pneumoniae strain TVO_1901936
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1923129..1933542

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ES276_RS09695 (ES276_10310)	-	1923824..1924648 (-)	825	WP_000727904.1	membrane protein insertase YidC	-
ES276_RS09700 (ES276_10315)	rnpA	1924623..1924994 (-)	372	WP_000739253.1	ribonuclease P protein component	-
ES276_RS10870	-	1925011..1925142 (-)	132	WP_000768904.1	hypothetical protein	-
ES276_RS09705 (ES276_10320)	-	1925143..1926333 (-)	1191	WP_000167757.1	acetate kinase	-
ES276_RS09710 (ES276_10325)	comGH	1926384..1927337 (-)	954	WP_000345135.1	class I SAM-dependent methyltransferase	Machinery gene
ES276_RS09715 (ES276_10330)	-	1927398..1927992 (-)	595	Protein_1916	class I SAM-dependent methyltransferase	-
ES276_RS09720 (ES276_10335)	comGG/cglG	1928129..1928542 (-)	414	WP_000265622.1	competence type IV pilus minor pilin ComGG	Machinery gene
ES276_RS09725 (ES276_10340)	comGF/cglF	1928520..1928981 (-)	462	WP_000250534.1	competence type IV pilus minor pilin ComGF	Machinery gene
ES276_RS09730 (ES276_10345)	comGE/cglE	1928944..1929246 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
ES276_RS09735 (ES276_10350)	comGD/cglD	1929209..1929613 (-)	405	WP_000588028.1	competence type IV pilus minor pilin ComGD	Machinery gene
ES276_RS09740 (ES276_10355)	comGC/cglC	1929606..1929932 (-)	327	WP_000738627.1	comG operon protein ComGC	Machinery gene
ES276_RS09745 (ES276_10360)	comGB/cglB	1929934..1930950 (-)	1017	WP_074196785.1	competence type IV pilus assembly protein ComGB	Machinery gene
ES276_RS09750 (ES276_10365)	comGA/cglA/cilD	1930898..1931839 (-)	942	WP_000249564.1	competence type IV pilus ATPase ComGA	Machinery gene
ES276_RS09755 (ES276_10370)	-	1931915..1932280 (-)	366	WP_000286415.1	DUF1033 family protein	-
ES276_RS09760 (ES276_10375)	-	1932431..1933489 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 137 a.a.
• Molecular weight: 16003.46 Da
• Isoelectric Point: 10.2472

>NTDB_id=310270 ES276_RS09720 WP_000265622.1 1928129..1928542(-) (comGG/cglG) [Streptococcus pneumoniae strain TVO_1901936]
MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQVAHYQDYALNKEKLVAFAMAKRTKDKVEQESGEQFFNLGQVSYQNKK
TGLVTRVRTDKSQYEFLFPSVKIKEEKRDKKEEVATDSSEKVEKKKSEEKPEKKENS

Nucleotide

• Length: 414 bp

>NTDB_id=310270 ES276_RS09720 WP_000265622.1 1928129..1928542(-) (comGG/cglG) [Streptococcus pneumoniae strain TVO_1901936]
GTGTGGAAAAAGAAAAAAGTTAAGGCAGGTGTTCTCCTCTACGCAGTCACCATAGCAGCCATCTTTAGTCTTTTGTTGCA
ATTTTATTTGAACCGACAAGTCGCCCACTATCAAGACTATGCTTTGAATAAAGAAAAATTGGTTGCTTTTGCTATGGCTA
AACGAACCAAAGATAAGGTTGAGCAAGAAAGTGGGGAACAGTTTTTTAATCTAGGTCAGGTAAGCTATCAAAACAAGAAA
ACTGGCTTAGTGACGAGGGTTCGTACGGATAAGAGCCAATATGAGTTTCTGTTTCCTTCAGTCAAAATCAAAGAAGAGAA
AAGAGATAAAAAGGAAGAGGTAGCGACCGATTCAAGCGAAAAAGTGGAGAAGAAAAAATCAGAAGAGAAGCCTGAAAAGA
AAGAGAATTCATAG

Domains

No domain identified.

3D structure

• AlphaFold DB: A0A0H2URX9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGG/cglG	Streptococcus pneumoniae Rx1	100	100	1
comGG/cglG	Streptococcus pneumoniae D39	100	100	1
comGG/cglG	Streptococcus pneumoniae R6	100	100	1
comGG/cglG	Streptococcus pneumoniae TIGR4	100	100	1
comGG/cglG	Streptococcus mitis SK321	87.591	100	0.876
comGG/cglG	Streptococcus mitis NCTC 12261	89.256	88.321	0.788
comGG	Streptococcus mutans UA140	38.806	97.81	0.38
comGG	Streptococcus mutans UA159	38.806	97.81	0.38