Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   ES276_RS09740 Genome accession   NZ_CP038252
Coordinates   1929606..1929932 (-) Length   108 a.a.
NCBI ID   WP_000738627.1    Uniprot ID   A0A0H2URU9
Organism   Streptococcus pneumoniae strain TVO_1901936     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1924606..1934932
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ES276_RS09700 (ES276_10315) rnpA 1924623..1924994 (-) 372 WP_000739253.1 ribonuclease P protein component -
  ES276_RS10870 - 1925011..1925142 (-) 132 WP_000768904.1 hypothetical protein -
  ES276_RS09705 (ES276_10320) - 1925143..1926333 (-) 1191 WP_000167757.1 acetate kinase -
  ES276_RS09710 (ES276_10325) comGH 1926384..1927337 (-) 954 WP_000345135.1 class I SAM-dependent methyltransferase Machinery gene
  ES276_RS09715 (ES276_10330) - 1927398..1927992 (-) 595 Protein_1916 class I SAM-dependent methyltransferase -
  ES276_RS09720 (ES276_10335) comGG/cglG 1928129..1928542 (-) 414 WP_000265622.1 competence type IV pilus minor pilin ComGG Machinery gene
  ES276_RS09725 (ES276_10340) comGF/cglF 1928520..1928981 (-) 462 WP_000250534.1 competence type IV pilus minor pilin ComGF Machinery gene
  ES276_RS09730 (ES276_10345) comGE/cglE 1928944..1929246 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  ES276_RS09735 (ES276_10350) comGD/cglD 1929209..1929613 (-) 405 WP_000588028.1 competence type IV pilus minor pilin ComGD Machinery gene
  ES276_RS09740 (ES276_10355) comGC/cglC 1929606..1929932 (-) 327 WP_000738627.1 comG operon protein ComGC Machinery gene
  ES276_RS09745 (ES276_10360) comGB/cglB 1929934..1930950 (-) 1017 WP_074196785.1 competence type IV pilus assembly protein ComGB Machinery gene
  ES276_RS09750 (ES276_10365) comGA/cglA/cilD 1930898..1931839 (-) 942 WP_000249564.1 competence type IV pilus ATPase ComGA Machinery gene
  ES276_RS09755 (ES276_10370) - 1931915..1932280 (-) 366 WP_000286415.1 DUF1033 family protein -
  ES276_RS09760 (ES276_10375) - 1932431..1933489 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  ES276_RS09765 (ES276_10380) nagA 1933652..1934803 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12177.34 Da        Isoelectric Point: 10.1876

>NTDB_id=310274 ES276_RS09740 WP_000738627.1 1929606..1929932(-) (comGC/cglC) [Streptococcus pneumoniae strain TVO_1901936]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDASLRKLQA
DGRITEEQAKAYKEYNDKNGGANRKVND

Nucleotide


Download         Length: 327 bp        

>NTDB_id=310274 ES276_RS09740 WP_000738627.1 1929606..1929932(-) (comGC/cglC) [Streptococcus pneumoniae strain TVO_1901936]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGGTGGAGATGTTGGTGGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTAGAAAAGAATGAAGATGCTAGCCTAAGAAAGTTACAAGCA
GATGGACGCATCACGGAAGAACAGGCTAAAGCTTATAAAGAATACAATGATAAAAATGGAGGAGCAAATCGTAAAGTCAA
TGATTAA

Domains

Predicted by InterProScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(11-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  PDB 5NCA

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus pneumoniae TIGR4

100

100

1
  comGC/cglC Streptococcus pneumoniae Rx1

99.074

100

0.991
  comGC/cglC Streptococcus pneumoniae D39

99.074

100

0.991
  comGC/cglC Streptococcus pneumoniae R6

99.074

100

0.991
  comGC/cglC Streptococcus mitis SK321

94.444

100

0.944
  comGC/cglC Streptococcus mitis NCTC 12261

94.898

90.741

0.861
  comGC Streptococcus gordonii str. Challis substr. CH1

67.961

95.37

0.648
  comGC Streptococcus mutans UA140

62.745

94.444

0.593
  comGC Streptococcus mutans UA159

62.745

94.444

0.593
  comGC Streptococcus suis isolate S10

70.37

75

0.528
  comGC Lactococcus lactis subsp. cremoris KW2

53.922

94.444

0.509
  comGC Staphylococcus aureus MW2

50

79.63

0.398
  comGC Staphylococcus aureus N315

50

79.63

0.398
  comGC Latilactobacillus sakei subsp. sakei 23K

45.349

79.63

0.361

Multiple sequence alignment