Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   SSA_RS01075 Genome accession   NC_009009
Coordinates   188296..189237 (+) Length   313 a.a.
NCBI ID   WP_011836358.1    Uniprot ID   A0AAW7NU72
Organism   Streptococcus sanguinis SK36     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 183296..194237
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SSA_RS01055 (SSA_0179) - 184106..184894 (+) 789 WP_002896779.1 hypothetical protein -
  SSA_RS11695 (SSA_0180) - 184906..185049 (+) 144 WP_002896778.1 hypothetical protein -
  SSA_RS01060 (SSA_0181) - 185042..186352 (+) 1311 WP_002896777.1 glycosyltransferase family 2 protein -
  SSA_RS01065 (SSA_0182) - 186361..187467 (+) 1107 WP_033179098.1 glycosyl hydrolase family 8 -
  SSA_RS01070 (SSA_0183) - 187786..188166 (+) 381 WP_011836357.1 DUF1033 family protein -
  SSA_RS01075 (SSA_0184) comYA 188296..189237 (+) 942 WP_011836358.1 competence type IV pilus ATPase ComGA Machinery gene
  SSA_RS01080 (SSA_0185) comYB 189167..190201 (+) 1035 WP_260469263.1 competence type IV pilus assembly protein ComGB Machinery gene
  SSA_RS01085 (SSA_0186) comYC 190201..190518 (+) 318 WP_011836360.1 competence type IV pilus major pilin ComGC Machinery gene
  SSA_RS01090 (SSA_0187) comYD 190478..190912 (+) 435 WP_033179099.1 competence type IV pilus minor pilin ComGD Machinery gene
  SSA_RS01095 (SSA_0188) comGE/cglE 190878..191171 (+) 294 WP_033179100.1 competence type IV pilus minor pilin ComGE Machinery gene
  SSA_RS01100 (SSA_0189) comGF/cglF 191155..191583 (+) 429 WP_011836363.1 competence type IV pilus minor pilin ComGF Machinery gene
  SSA_RS01105 (SSA_0190) comGG 191573..191965 (+) 393 WP_033179101.1 competence type IV pilus minor pilin ComGG -
  SSA_RS01110 (SSA_0191) comYH 192047..193012 (+) 966 WP_002910847.1 class I SAM-dependent methyltransferase Machinery gene

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35811.07 Da        Isoelectric Point: 6.3959

>NTDB_id=27497 SSA_RS01075 WP_011836358.1 188296..189237(+) (comYA) [Streptococcus sanguinis SK36]
MVQEIAKEMIRQARQEGAQDIYLIPKSTCYELYMRIGDERRFIKTYDFELLSAVISHFKFVAGMNVGEKRRSQLGSCDYD
CGEAKVSIRLSTVGDYRGFESLVIRLLHDEDRELRFWFEQLPELRKKIQARGLYLFSGPVGSGKTTLMYHLAQLKFSGQQ
VMSIEDPVEIKQEAMLQLQLNETIGMTYDSLIKLSLRHRPDLLIIGEIRDRETARAVVRASLTGATVFSTIHAKSVRGVY
ERLLELGVSEDELRMVLQGVCYQRLIGGGGVVDFVSQNYQEHEAAVWNQQIDQLFAEGHISAEQRQTEKIVYA

Nucleotide


Download         Length: 942 bp        

>NTDB_id=27497 SSA_RS01075 WP_011836358.1 188296..189237(+) (comYA) [Streptococcus sanguinis SK36]
ATGGTTCAAGAAATTGCAAAAGAAATGATTAGGCAGGCTCGGCAAGAAGGAGCGCAGGATATTTACCTCATTCCTAAGAG
TACTTGCTATGAGCTTTATATGAGAATTGGTGATGAACGCCGCTTTATAAAGACTTATGATTTTGAACTTCTGTCAGCTG
TTATTAGCCACTTTAAGTTTGTCGCAGGTATGAATGTTGGAGAGAAGCGCCGCAGTCAGCTGGGGTCTTGCGATTATGAC
TGTGGGGAAGCCAAGGTTTCAATCCGGCTGTCAACAGTTGGTGATTACCGTGGTTTTGAAAGTCTGGTCATCCGACTCCT
TCATGACGAAGACAGGGAGCTGCGCTTTTGGTTTGAGCAATTGCCGGAGCTGCGCAAGAAAATTCAGGCTCGGGGACTCT
ATCTTTTCTCAGGACCAGTTGGCAGTGGCAAGACGACCTTGATGTACCATTTGGCTCAGCTCAAATTTTCTGGCCAGCAG
GTTATGTCGATTGAAGATCCGGTTGAGATTAAGCAAGAGGCTATGCTGCAGCTGCAGCTGAACGAAACCATTGGCATGAC
TTATGACAGTCTAATTAAGCTGTCTCTGCGACATCGTCCTGATCTCTTGATTATCGGGGAAATCCGTGATCGAGAGACAG
CTAGGGCGGTGGTTCGGGCAAGTCTGACCGGAGCTACGGTCTTTTCAACGATTCATGCCAAGAGTGTTCGCGGTGTCTAT
GAGCGGCTTTTGGAATTGGGCGTTAGCGAGGATGAGCTAAGAATGGTGCTGCAAGGTGTTTGTTACCAGCGTTTAATTGG
GGGAGGAGGTGTCGTTGATTTTGTCAGTCAAAACTATCAAGAGCACGAAGCCGCAGTCTGGAATCAGCAGATTGATCAGC
TTTTTGCAGAAGGACATATCAGTGCTGAGCAAAGGCAGACCGAAAAAATTGTCTACGCCTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

80.645

99.042

0.799
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

75.08

100

0.751
  comGA/cglA/cilD Streptococcus pneumoniae D39

75.08

100

0.751
  comGA/cglA/cilD Streptococcus pneumoniae R6

75.08

100

0.751
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

75.08

100

0.751
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

74.76

100

0.748
  comYA Streptococcus mutans UA159

65.916

99.361

0.655
  comYA Streptococcus mutans UA140

65.916

99.361

0.655
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

64.839

99.042

0.642
  comGA Lactococcus lactis subsp. cremoris KW2

55.128

99.681

0.55
  comGA Latilactobacillus sakei subsp. sakei 23K

41.007

88.818

0.364

Multiple sequence alignment