Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   SSA_RS01095 Genome accession   NC_009009
Coordinates   190878..191171 (+) Length   97 a.a.
NCBI ID   WP_033179100.1    Uniprot ID   -
Organism   Streptococcus sanguinis SK36     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 185878..196171
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SSA_RS01065 (SSA_0182) - 186361..187467 (+) 1107 WP_033179098.1 glycosyl hydrolase family 8 -
  SSA_RS01070 (SSA_0183) - 187786..188166 (+) 381 WP_011836357.1 DUF1033 family protein -
  SSA_RS01075 (SSA_0184) comYA 188296..189237 (+) 942 WP_011836358.1 competence type IV pilus ATPase ComGA Machinery gene
  SSA_RS01080 (SSA_0185) comYB 189167..190201 (+) 1035 WP_260469263.1 competence type IV pilus assembly protein ComGB Machinery gene
  SSA_RS01085 (SSA_0186) comYC 190201..190518 (+) 318 WP_011836360.1 competence type IV pilus major pilin ComGC Machinery gene
  SSA_RS01090 (SSA_0187) comYD 190478..190912 (+) 435 WP_033179099.1 competence type IV pilus minor pilin ComGD Machinery gene
  SSA_RS01095 (SSA_0188) comGE/cglE 190878..191171 (+) 294 WP_033179100.1 competence type IV pilus minor pilin ComGE Machinery gene
  SSA_RS01100 (SSA_0189) comGF/cglF 191155..191583 (+) 429 WP_011836363.1 competence type IV pilus minor pilin ComGF Machinery gene
  SSA_RS01105 (SSA_0190) comGG 191573..191965 (+) 393 WP_033179101.1 competence type IV pilus minor pilin ComGG -
  SSA_RS01110 (SSA_0191) comYH 192047..193012 (+) 966 WP_002910847.1 class I SAM-dependent methyltransferase Machinery gene
  SSA_RS01115 (SSA_0192) - 193049..194242 (+) 1194 WP_002911070.1 acetate kinase -
  SSA_RS01120 (SSA_0193) - 194386..195135 (+) 750 WP_033179102.1 CPBP family intramembrane glutamic endopeptidase -
  SSA_RS01125 (SSA_0195) - 195253..195891 (+) 639 WP_011836366.1 type II CAAX prenyl endopeptidase Rce1 family protein -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10883.90 Da        Isoelectric Point: 10.9436

>NTDB_id=27501 SSA_RS01095 WP_033179100.1 190878..191171(+) (comGE/cglE) [Streptococcus sanguinis SK36]
MASLKRRQLQASILLEALVAMAVFATIASLLLGQISRSRKGQQILLQQEEVLRVARMALQTGQEELHINGIAVRQLKTDK
QLLVYHEGEVVIRVQKP

Nucleotide


Download         Length: 294 bp        

>NTDB_id=27501 SSA_RS01095 WP_033179100.1 190878..191171(+) (comGE/cglE) [Streptococcus sanguinis SK36]
ATGGCAAGTTTAAAAAGACGACAGCTTCAAGCTAGTATTCTGCTGGAAGCTCTGGTGGCCATGGCAGTTTTTGCGACTAT
TGCCAGTCTGCTTTTGGGCCAGATTAGTCGGTCTCGTAAGGGGCAGCAGATCCTTTTGCAGCAGGAAGAGGTGCTTCGGG
TAGCCCGTATGGCTCTGCAAACAGGACAAGAAGAGCTTCATATCAATGGAATTGCAGTGCGTCAGCTTAAGACAGATAAG
CAGCTGCTGGTCTATCACGAAGGGGAGGTAGTTATTCGTGTCCAAAAACCTTAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae TIGR4

48.454

100

0.485
  comGE/cglE Streptococcus pneumoniae Rx1

48.454

100

0.485
  comGE/cglE Streptococcus pneumoniae D39

48.454

100

0.485
  comGE/cglE Streptococcus pneumoniae R6

48.454

100

0.485
  comGE/cglE Streptococcus mitis NCTC 12261

47.423

100

0.474
  comGE/cglE Streptococcus mitis SK321

47.423

100

0.474
  comYE Streptococcus mutans UA140

42.268

100

0.423
  comYE Streptococcus mutans UA159

42.268

100

0.423

Multiple sequence alignment