Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   SSA_RS01080 Genome accession   NC_009009
Coordinates   189167..190201 (+) Length   344 a.a.
NCBI ID   WP_260469263.1    Uniprot ID   -
Organism   Streptococcus sanguinis SK36     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 184167..195201
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SSA_RS11695 (SSA_0180) - 184906..185049 (+) 144 WP_002896778.1 hypothetical protein -
  SSA_RS01060 (SSA_0181) - 185042..186352 (+) 1311 WP_002896777.1 glycosyltransferase family 2 protein -
  SSA_RS01065 (SSA_0182) - 186361..187467 (+) 1107 WP_033179098.1 glycosyl hydrolase family 8 -
  SSA_RS01070 (SSA_0183) - 187786..188166 (+) 381 WP_011836357.1 DUF1033 family protein -
  SSA_RS01075 (SSA_0184) comYA 188296..189237 (+) 942 WP_011836358.1 competence type IV pilus ATPase ComGA Machinery gene
  SSA_RS01080 (SSA_0185) comYB 189167..190201 (+) 1035 WP_260469263.1 competence type IV pilus assembly protein ComGB Machinery gene
  SSA_RS01085 (SSA_0186) comYC 190201..190518 (+) 318 WP_011836360.1 competence type IV pilus major pilin ComGC Machinery gene
  SSA_RS01090 (SSA_0187) comYD 190478..190912 (+) 435 WP_033179099.1 competence type IV pilus minor pilin ComGD Machinery gene
  SSA_RS01095 (SSA_0188) comGE/cglE 190878..191171 (+) 294 WP_033179100.1 competence type IV pilus minor pilin ComGE Machinery gene
  SSA_RS01100 (SSA_0189) comGF/cglF 191155..191583 (+) 429 WP_011836363.1 competence type IV pilus minor pilin ComGF Machinery gene
  SSA_RS01105 (SSA_0190) comGG 191573..191965 (+) 393 WP_033179101.1 competence type IV pilus minor pilin ComGG -
  SSA_RS01110 (SSA_0191) comYH 192047..193012 (+) 966 WP_002910847.1 class I SAM-dependent methyltransferase Machinery gene
  SSA_RS01115 (SSA_0192) - 193049..194242 (+) 1194 WP_002911070.1 acetate kinase -
  SSA_RS01120 (SSA_0193) - 194386..195135 (+) 750 WP_033179102.1 CPBP family intramembrane glutamic endopeptidase -

Sequence

Protein


Download         Length: 344 a.a.        Molecular weight: 39055.02 Da        Isoelectric Point: 9.1627

>NTDB_id=27498 SSA_RS01080 WP_260469263.1 189167..190201(+) (comYB) [Streptococcus sanguinis SK36]
MISFLQKDISVLSKGRPKKLSTPKQKKIIELFHNLFSSGFHLAEIVDFLRRSALLEEVYVTEMRAGLSAGQSFSEIVSRL
GFSDSVVTQLSLSELHGNLTLSLGKIEAYLENLSKVKKKLIEVGTYPLMLLGFLVLIMLGLRNYLLPQLDSQNLATQLIN
HLPQIFLWSSLVLAILVSLAVFYYRKSSKIRFFSKLAALPFFGRLVQAYLTAYYAREWGNMIGQGLELSQIFAIMQEQPS
QLFQEIGEDMAAALQGGQGYADKVASYPFFKKELSLMIEYGEVKSKLGSELEVYAEKTWEEFFLRINRAMNFIQPLVFIF
VALVIVLLYAAMLLPIYQNMEVHL

Nucleotide


Download         Length: 1035 bp        

>NTDB_id=27498 SSA_RS01080 WP_260469263.1 189167..190201(+) (comYB) [Streptococcus sanguinis SK36]
TTGATCAGCTTTTTGCAGAAGGACATATCAGTGCTGAGCAAAGGCAGACCGAAAAAATTGTCTACGCCTAAGCAGAAAAA
GATTATTGAGCTCTTTCATAATCTCTTTAGCAGCGGTTTTCACTTAGCAGAGATTGTAGACTTTCTGAGACGAAGTGCTT
TGCTGGAGGAAGTATATGTCACTGAAATGCGGGCAGGCTTGTCAGCTGGTCAGTCCTTTTCAGAGATTGTCAGTCGACTG
GGATTTTCCGACAGCGTTGTAACCCAGCTTTCCTTATCTGAGCTGCATGGTAATCTGACACTTAGTCTGGGCAAAATTGA
GGCCTATCTGGAAAATCTGTCCAAGGTTAAGAAAAAATTGATAGAGGTAGGGACCTATCCTCTCATGCTGCTGGGCTTTT
TGGTCCTTATCATGCTGGGCTTGCGCAACTATCTTCTGCCTCAATTAGACAGCCAGAATCTAGCTACTCAGCTGATTAAT
CACCTGCCTCAGATCTTTTTATGGAGCAGCCTTGTTTTAGCTATCTTGGTTTCATTGGCTGTCTTTTACTATCGAAAGTC
TTCCAAGATTCGTTTTTTCAGCAAACTAGCAGCTCTGCCCTTTTTTGGACGTTTGGTACAGGCTTACTTGACCGCTTATT
ATGCTCGTGAATGGGGAAATATGATTGGCCAGGGCTTGGAACTGAGTCAGATTTTTGCGATTATGCAGGAGCAGCCTTCC
CAGCTCTTTCAGGAAATCGGAGAAGATATGGCGGCTGCTTTGCAGGGCGGTCAGGGCTATGCGGACAAGGTGGCAAGCTA
TCCTTTCTTTAAGAAAGAATTGTCCTTGATGATCGAGTATGGTGAGGTCAAGTCCAAGCTAGGCAGTGAGCTGGAAGTCT
ATGCTGAAAAGACTTGGGAGGAGTTTTTCCTACGTATCAATCGAGCCATGAATTTCATTCAGCCCCTAGTATTTATTTTT
GTTGCCTTAGTGATTGTTTTACTTTATGCGGCAATGCTCTTGCCCATTTATCAGAATATGGAGGTTCATTTGTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(215-335)

Type II secretion system (T2SS), protein F (T2SSF)

(29-147)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

74.128

100

0.741
  comGB/cglB Streptococcus mitis NCTC 12261

70.536

97.674

0.689
  comGB/cglB Streptococcus mitis SK321

69.345

97.674

0.677
  comGB/cglB Streptococcus pneumoniae TIGR4

68.452

97.674

0.669
  comGB/cglB Streptococcus pneumoniae R6

68.452

97.674

0.669
  comGB/cglB Streptococcus pneumoniae Rx1

68.452

97.674

0.669
  comGB/cglB Streptococcus pneumoniae D39

68.452

97.674

0.669
  comYB Streptococcus mutans UA140

60.933

99.709

0.608
  comYB Streptococcus mutans UA159

60.933

99.709

0.608
  comGB Lactococcus lactis subsp. cremoris KW2

51.039

97.965

0.5

Multiple sequence alignment