Detailed information NTG0027503

Bioinformatically predicted

Overview

• Name: comYH
• Type: Machinery gene
• Locus tag: SSA_RS01110
• Genome accession: NC_009009
• Coordinates: 192047..193012 (+)
• Length: 321 a.a.
• NCBI ID: WP_002910847.1
• Uniprot ID: A3CKE8
• Organism: Streptococcus sanguinis SK36
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 187047..198012

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SSA_RS01070 (SSA_0183)	-	187786..188166 (+)	381	WP_011836357.1	DUF1033 family protein	-
SSA_RS01075 (SSA_0184)	comYA	188296..189237 (+)	942	WP_011836358.1	competence type IV pilus ATPase ComGA	Machinery gene
SSA_RS01080 (SSA_0185)	comYB	189167..190201 (+)	1035	WP_260469263.1	competence type IV pilus assembly protein ComGB	Machinery gene
SSA_RS01085 (SSA_0186)	comYC	190201..190518 (+)	318	WP_011836360.1	competence type IV pilus major pilin ComGC	Machinery gene
SSA_RS01090 (SSA_0187)	comYD	190478..190912 (+)	435	WP_033179099.1	competence type IV pilus minor pilin ComGD	Machinery gene
SSA_RS01095 (SSA_0188)	comGE/cglE	190878..191171 (+)	294	WP_033179100.1	competence type IV pilus minor pilin ComGE	Machinery gene
SSA_RS01100 (SSA_0189)	comGF/cglF	191155..191583 (+)	429	WP_011836363.1	competence type IV pilus minor pilin ComGF	Machinery gene
SSA_RS01105 (SSA_0190)	comGG	191573..191965 (+)	393	WP_033179101.1	competence type IV pilus minor pilin ComGG	-
SSA_RS01110 (SSA_0191)	comYH	192047..193012 (+)	966	WP_002910847.1	class I SAM-dependent methyltransferase	Machinery gene
SSA_RS01115 (SSA_0192)	-	193049..194242 (+)	1194	WP_002911070.1	acetate kinase	-
SSA_RS01120 (SSA_0193)	-	194386..195135 (+)	750	WP_033179102.1	CPBP family intramembrane glutamic endopeptidase	-
SSA_RS01125 (SSA_0195)	-	195253..195891 (+)	639	WP_011836366.1	type II CAAX prenyl endopeptidase Rce1 family protein	-
SSA_RS01130 (SSA_0197)	folP	196086..197039 (+)	954	WP_011836367.1	dihydropteroate synthase	-

Sequence

Protein

• Length: 321 a.a.
• Molecular weight: 36672.63 Da
• Isoelectric Point: 4.6183

>NTDB_id=27503 SSA_RS01110 WP_002910847.1 192047..193012(+) (comYH) [Streptococcus sanguinis SK36]
MNFEKIEQAYTLILENVQNIQNALSTNFYDALIEQNGIYLDGDTDLQEVLANDEKIRALHLNKEEWRRAYQFILMKAAQT
EPMQVNHQFTPDTIGFLITFLLDQLAHGEEADVLEIGSGTGNLAETILNHTQKKIDYLGLELDDLLIDLSASIAEVMNSK
AHFAQGDAVRPQVLKESDIIISDLPVGYYPDDSIASRYEVASPDEHTYAHHLLMEQSLKYLKPGGYAIFLAPNDLLTSAQ
APLLKKWLLAKAQFIAMITLPESIFSSSKHAKTLFVLRKQEANNIQPFIYPLRDLQDHDEMFKFRQSFQNWYKDSEIQTK
F

Nucleotide

• Length: 966 bp

>NTDB_id=27503 SSA_RS01110 WP_002910847.1 192047..193012(+) (comYH) [Streptococcus sanguinis SK36]
ATGAATTTTGAAAAGATAGAACAAGCTTATACTCTGATTCTCGAAAACGTCCAGAATATCCAAAACGCTCTGTCGACTAA
TTTTTACGATGCTCTGATTGAGCAGAACGGCATTTACCTAGATGGAGATACGGATTTACAAGAAGTTCTGGCCAACGATG
AAAAAATCCGCGCTCTGCATTTGAACAAGGAAGAGTGGCGGAGAGCTTATCAGTTTATCCTGATGAAGGCTGCCCAGACG
GAGCCCATGCAGGTCAATCATCAATTCACACCTGACACAATTGGTTTTCTGATTACTTTCTTATTGGACCAGCTAGCTCA
CGGAGAGGAAGCTGATGTATTAGAAATCGGCAGCGGAACAGGAAATTTGGCTGAGACTATTCTCAATCATACCCAAAAGA
AGATTGACTACTTAGGTCTGGAGCTAGATGATTTATTAATTGACCTTTCTGCTAGTATTGCAGAGGTTATGAATTCTAAG
GCTCACTTTGCTCAGGGGGATGCAGTTCGACCTCAGGTTCTGAAAGAGAGTGATATCATTATCAGTGATTTACCGGTTGG
TTATTATCCAGACGACAGTATCGCCTCCCGATATGAAGTGGCTAGTCCGGATGAGCACACTTATGCCCATCATCTTCTGA
TGGAGCAATCGCTCAAATATCTGAAGCCAGGTGGTTATGCTATATTTCTGGCGCCAAATGATCTCTTGACCAGCGCTCAA
GCTCCTCTGCTGAAAAAATGGCTCCTCGCCAAGGCTCAGTTTATTGCGATGATAACCTTACCAGAATCTATTTTCTCAAG
CAGCAAGCATGCTAAAACTCTTTTTGTCTTGAGGAAGCAAGAAGCGAATAACATTCAGCCTTTTATCTATCCTCTGCGGG
ATTTGCAGGATCATGATGAAATGTTTAAATTCCGTCAAAGTTTTCAAAACTGGTACAAAGATAGTGAAATTCAAACAAAA
TTTTGA

Domains

Predicted by InterproScan.

• N-6 DNA Methylase (N6_Mtase) (68-290)

3D structure

• AlphaFold DB: A3CKE8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYH	Streptococcus mutans UA159	58.73	98.131	0.576
comYH	Streptococcus mutans UA140	58.413	98.131	0.573