Detailed information NTG0262326

Bioinformatically predicted

Overview

• Name: comYC
• Type: Machinery gene
• Locus tag: C0J00_RS00795
• Genome accession: NZ_CP025536
• Coordinates: 145419..145712 (+)
• Length: 97 a.a.
• NCBI ID: WP_104967106.1
• Uniprot ID: A0A2L0D238
• Organism: Streptococcus pluranimalium strain TH11417
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 140419..150712

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C0J00_RS00780 (C0J00_00780)	-	143070..143450 (+)	381	WP_205407082.1	DUF1033 family protein	-
C0J00_RS00785 (C0J00_00785)	comYA	143513..144466 (+)	954	WP_104967105.1	competence type IV pilus ATPase ComGA	Machinery gene
C0J00_RS00790 (C0J00_00790)	comYB	144390..145418 (+)	1029	WP_199773983.1	competence type IV pilus assembly protein ComGB	Machinery gene
C0J00_RS00795 (C0J00_00795)	comYC	145419..145712 (+)	294	WP_104967106.1	competence type IV pilus major pilin ComGC	Machinery gene
C0J00_RS00800 (C0J00_00800)	comGD	145693..146109 (+)	417	WP_104967107.1	competence type IV pilus minor pilin ComGD	-
C0J00_RS00805 (C0J00_00805)	comGE	146081..146380 (+)	300	WP_104967108.1	competence type IV pilus minor pilin ComGE	-
C0J00_RS00810 (C0J00_00810)	comYF	146340..146795 (+)	456	WP_407697186.1	competence type IV pilus minor pilin ComGF	Machinery gene
C0J00_RS00815 (C0J00_00815)	comGG	146779..147174 (+)	396	WP_199773973.1	competence type IV pilus minor pilin ComGG	-
C0J00_RS00820 (C0J00_00820)	comYH	147217..148170 (+)	954	WP_104967110.1	class I SAM-dependent methyltransferase	Machinery gene
C0J00_RS00825 (C0J00_00825)	-	148231..149421 (+)	1191	WP_104967111.1	acetate kinase	-
C0J00_RS00830 (C0J00_00830)	-	149807..150004 (+)	198	WP_104967112.1	helix-turn-helix transcriptional regulator	-
C0J00_RS00835 (C0J00_00835)	-	150017..150469 (+)	453	WP_104967113.1	hypothetical protein	-

Sequence

Protein

• Length: 97 a.a.
• Molecular weight: 11076.17 Da
• Isoelectric Point: 9.8115

>NTDB_id=262326 C0J00_RS00795 WP_104967106.1 145419..145712(+) (comYC) [Streptococcus pluranimalium strain TH11417]
MTYYWKQIKRKSVKGFTLLEMLFVLLIISVLMLLFVPNLSKQKAAVDEKGKAAVVKVVESQMELYEMKEDAKPSIQQLVD
GGYITQKQADTYAEAKK

Nucleotide

• Length: 294 bp

>NTDB_id=262326 C0J00_RS00795 WP_104967106.1 145419..145712(+) (comYC) [Streptococcus pluranimalium strain TH11417]
GTGACATATTATTGGAAACAAATTAAACGAAAAAGTGTAAAAGGGTTCACTCTTCTAGAAATGCTCTTCGTGCTTCTTAT
CATCAGTGTGCTTATGCTTTTGTTTGTGCCTAATTTGAGCAAGCAAAAGGCGGCTGTTGATGAAAAAGGAAAGGCAGCAG
TGGTGAAGGTTGTCGAGAGTCAGATGGAGTTGTATGAAATGAAAGAAGATGCCAAACCATCTATTCAACAATTAGTGGAT
GGTGGTTATATTACGCAAAAGCAAGCTGATACTTATGCAGAAGCTAAGAAGTAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (10-34)

3D structure

• AlphaFold DB: A0A2L0D238

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYC	Streptococcus suis isolate S10	67.059	87.629	0.588
comYC	Streptococcus gordonii str. Challis substr. CH1	63.636	90.722	0.577
comGC/cglC	Streptococcus pneumoniae D39	62.069	89.691	0.557
comGC/cglC	Streptococcus pneumoniae R6	62.069	89.691	0.557
comGC/cglC	Streptococcus pneumoniae TIGR4	62.069	89.691	0.557
comGC/cglC	Streptococcus mitis SK321	62.069	89.691	0.557
comGC/cglC	Streptococcus mitis NCTC 12261	62.069	89.691	0.557
comGC/cglC	Streptococcus pneumoniae Rx1	62.069	89.691	0.557
comYC	Streptococcus mutans UA140	59.551	91.753	0.546
comYC	Streptococcus mutans UA159	59.551	91.753	0.546
comGC	Lactococcus lactis subsp. cremoris KW2	54.348	94.845	0.515
comGC	Staphylococcus aureus MW2	46.835	81.443	0.381
comGC	Staphylococcus aureus N315	46.835	81.443	0.381