Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   C0J00_RS00785 Genome accession   NZ_CP025536
Coordinates   143513..144466 (+) Length   317 a.a.
NCBI ID   WP_104967105.1    Uniprot ID   A0A2L0D1S8
Organism   Streptococcus pluranimalium strain TH11417     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 138513..149466
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C0J00_RS00775 (C0J00_00775) rpoC 139060..142692 (+) 3633 WP_104967104.1 DNA-directed RNA polymerase subunit beta' -
  C0J00_RS00780 (C0J00_00780) - 143070..143450 (+) 381 WP_205407082.1 DUF1033 family protein -
  C0J00_RS00785 (C0J00_00785) comYA 143513..144466 (+) 954 WP_104967105.1 competence type IV pilus ATPase ComGA Machinery gene
  C0J00_RS00790 (C0J00_00790) comYB 144390..145418 (+) 1029 WP_199773983.1 competence type IV pilus assembly protein ComGB Machinery gene
  C0J00_RS00795 (C0J00_00795) comYC 145419..145712 (+) 294 WP_104967106.1 competence type IV pilus major pilin ComGC Machinery gene
  C0J00_RS00800 (C0J00_00800) comGD 145693..146109 (+) 417 WP_104967107.1 competence type IV pilus minor pilin ComGD -
  C0J00_RS00805 (C0J00_00805) comGE 146081..146380 (+) 300 WP_104967108.1 competence type IV pilus minor pilin ComGE -
  C0J00_RS00810 (C0J00_00810) comYF 146340..146795 (+) 456 WP_407697186.1 competence type IV pilus minor pilin ComGF Machinery gene
  C0J00_RS00815 (C0J00_00815) comGG 146779..147174 (+) 396 WP_199773973.1 competence type IV pilus minor pilin ComGG -
  C0J00_RS00820 (C0J00_00820) comYH 147217..148170 (+) 954 WP_104967110.1 class I SAM-dependent methyltransferase Machinery gene
  C0J00_RS00825 (C0J00_00825) - 148231..149421 (+) 1191 WP_104967111.1 acetate kinase -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35813.80 Da        Isoelectric Point: 5.6730

>NTDB_id=262324 C0J00_RS00785 WP_104967105.1 143513..144466(+) (comYA) [Streptococcus pluranimalium strain TH11417]
MVQDLAKELIVQAVEYEAQDIYIIPRKNDYDVFMRINDERRFIETHGFDRMASLISHFKFVAGMTVGEKRRSQLGSCDYD
IGSAKLVSLRLSTVGDYRGHESLVIRLLHDGRQDLRYWFNGIRNIMAEFSSRGLYLFSGPTGSGKTTLMYQLLKETCKDK
QIISIEDPVEIKDDSILQLQLNEDIGMTYDSLIKLSLRHRPDVLVIGEIRDTQTAQAAIRASLTGATVFATIHAKSIPGV
YYRMIELGVSKDDLKNSLAGVCYQRLIGGGGLIDVAKDKFQDHSPSQWNQYLVELFEAGYITEEQVKTESISYSEAG

Nucleotide


Download         Length: 954 bp        

>NTDB_id=262324 C0J00_RS00785 WP_104967105.1 143513..144466(+) (comYA) [Streptococcus pluranimalium strain TH11417]
ATGGTTCAAGATTTAGCAAAGGAACTGATTGTTCAGGCAGTCGAATATGAAGCTCAAGATATTTATATTATTCCTAGAAA
GAATGATTACGATGTTTTTATGCGTATTAATGATGAGAGGAGATTTATTGAAACTCATGGCTTTGATCGGATGGCTAGTC
TTATTAGTCACTTTAAATTTGTGGCAGGAATGACTGTCGGGGAAAAGCGCCGAAGTCAACTAGGATCTTGTGATTATGAT
ATTGGTAGTGCTAAGCTAGTTTCTTTACGCCTCTCAACTGTTGGAGATTACCGAGGGCATGAGAGTTTGGTGATTCGCTT
GCTGCATGATGGGCGTCAGGACTTACGCTATTGGTTCAATGGTATACGTAATATCATGGCAGAATTTAGTTCCAGAGGTC
TATATCTTTTTTCGGGACCGACTGGGAGCGGCAAAACGACTCTCATGTATCAATTGTTAAAGGAAACATGTAAAGATAAA
CAGATTATTTCTATTGAAGATCCGGTTGAAATTAAGGATGATAGCATTTTACAATTACAGCTTAATGAAGATATTGGTAT
GACTTACGATAGTCTGATTAAGTTGTCGTTGAGACATCGTCCAGATGTATTGGTTATTGGTGAAATTCGGGATACGCAAA
CAGCGCAAGCGGCTATTCGAGCTAGTTTGACTGGTGCTACAGTCTTTGCAACCATTCATGCTAAGAGTATTCCAGGGGTT
TATTACCGCATGATAGAATTGGGTGTTTCTAAAGATGATCTAAAAAATAGTCTGGCAGGAGTTTGTTATCAACGTTTGAT
AGGAGGAGGTGGATTGATAGATGTGGCAAAAGATAAGTTCCAGGATCACTCACCAAGCCAGTGGAACCAATACTTGGTTG
AGCTTTTTGAAGCAGGATATATCACTGAGGAGCAGGTTAAAACCGAGAGTATTAGCTATTCAGAAGCAGGTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2L0D1S8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

65.916

98.107

0.647
  comYA Streptococcus mutans UA140

65.916

98.107

0.647
  comYA Streptococcus gordonii str. Challis substr. CH1

62.975

99.685

0.628
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

62.102

99.054

0.615
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

61.783

99.054

0.612
  comGA/cglA/cilD Streptococcus pneumoniae R6

61.783

99.054

0.612
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

61.783

99.054

0.612
  comGA/cglA/cilD Streptococcus pneumoniae D39

61.783

99.054

0.612
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

62.258

97.792

0.609
  comGA Lactococcus lactis subsp. cremoris KW2

51.735

100

0.517

Multiple sequence alignment