Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   A6J72_RS06560 Genome accession   NZ_CP020433
Coordinates   1307759..1308700 (+) Length   313 a.a.
NCBI ID   WP_003073980.1    Uniprot ID   -
Organism   Streptococcus intermedius strain FDAARGOS_233     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1302759..1313700
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J72_RS06535 (A6J72_06545) - 1303897..1304577 (+) 681 WP_003075761.1 CHAP domain-containing protein -
  A6J72_RS06540 (A6J72_06550) - 1304752..1305282 (+) 531 WP_003073971.1 aromatic acid exporter family protein -
  A6J72_RS06545 (A6J72_06555) - 1305359..1305718 (+) 360 WP_003073972.1 MerR family transcriptional regulator -
  A6J72_RS06550 (A6J72_06560) glnA 1305757..1307103 (+) 1347 WP_082312039.1 type I glutamate--ammonia ligase -
  A6J72_RS06555 (A6J72_06565) - 1307325..1307690 (+) 366 WP_003075933.1 DUF1033 family protein -
  A6J72_RS06560 (A6J72_06570) comYA 1307759..1308700 (+) 942 WP_003073980.1 competence type IV pilus ATPase ComGA Machinery gene
  A6J72_RS06565 (A6J72_06575) comYB 1308642..1309664 (+) 1023 WP_192573659.1 competence type IV pilus assembly protein ComGB Machinery gene
  A6J72_RS06570 (A6J72_06580) comYC 1309661..1309978 (+) 318 WP_082312041.1 competence type IV pilus major pilin ComGC Machinery gene
  A6J72_RS06575 (A6J72_06585) comYD 1309938..1310366 (+) 429 WP_037582814.1 competence type IV pilus minor pilin ComGD Machinery gene
  A6J72_RS06580 (A6J72_06590) comGE/cglE 1310338..1310631 (+) 294 WP_003073987.1 competence type IV pilus minor pilin ComGE Machinery gene
  A6J72_RS06585 (A6J72_06595) comGF/cglF 1310615..1311052 (+) 438 WP_003073990.1 competence type IV pilus minor pilin ComGF Machinery gene
  A6J72_RS06590 (A6J72_06600) comGG 1311033..1311359 (+) 327 WP_263969846.1 competence type IV pilus minor pilin ComGG -
  A6J72_RS06595 (A6J72_06605) comYH 1311450..1312403 (+) 954 WP_105255939.1 class I SAM-dependent methyltransferase Machinery gene
  A6J72_RS06600 (A6J72_06610) - 1312450..1313649 (+) 1200 WP_021003254.1 acetate kinase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 36048.41 Da        Isoelectric Point: 7.8529

>NTDB_id=223009 A6J72_RS06560 WP_003073980.1 1307759..1308700(+) (comYA) [Streptococcus intermedius strain FDAARGOS_233]
MVQNIAQDIICQAKEKQAQDIYFIPKENSYELYMRIGDERRFIQQYAFEKMAAVISHFKFTAGMNVGEKRRSQLGSCDYQ
YRDKKTSLRLSTVGDYRGYESLVIRLLHDEKAELKFWFAQIPELKGRLKQRGLYLFSGPVGSGKTTLMHQLAQERFADEQ
IMSIEDPVEIKQDRMLQLQLNEAIGLTYESLIKLSLRHRPDLLIIGEIRDTETARAVVRASLTGVTVFSTIHAKSVRGVY
ERLLELGVTEAELKIVLQGICYQRLIAKGGIVDFVSERYQEHDPSEWNRQIDQLYAAGHINLEQAKAEKIIHS

Nucleotide


Download         Length: 942 bp        

>NTDB_id=223009 A6J72_RS06560 WP_003073980.1 1307759..1308700(+) (comYA) [Streptococcus intermedius strain FDAARGOS_233]
ATGGTTCAAAACATTGCACAAGATATTATTTGCCAAGCTAAGGAAAAACAGGCTCAAGATATTTATTTTATCCCAAAGGA
AAATAGTTATGAACTGTACATGAGAATTGGTGATGAGCGACGTTTTATACAACAGTATGCATTTGAAAAGATGGCAGCGG
TGATTAGTCATTTCAAATTTACTGCTGGGATGAATGTTGGTGAAAAACGTAGAAGCCAACTAGGGTCTTGTGATTATCAA
TACAGGGATAAGAAAACATCACTGCGGTTGTCAACAGTAGGGGATTATCGCGGATATGAAAGTCTTGTGATTCGTTTATT
GCATGATGAAAAAGCAGAGTTGAAGTTTTGGTTTGCTCAAATTCCAGAGTTGAAAGGACGACTCAAGCAACGTGGACTTT
ATCTTTTTTCAGGACCGGTAGGGAGTGGCAAAACCACTCTTATGCATCAGCTGGCTCAAGAACGTTTTGCCGATGAGCAA
ATCATGTCTATCGAAGATCCTGTTGAAATTAAGCAAGACAGAATGTTGCAATTGCAATTGAATGAAGCGATTGGCTTAAC
TTATGAAAGTTTGATTAAACTTTCTCTTCGACATCGTCCAGATTTATTGATTATTGGAGAAATTCGAGATACAGAAACAG
CACGGGCGGTTGTACGAGCCAGCTTGACAGGAGTGACGGTCTTTTCAACGATTCATGCTAAAAGTGTGCGAGGCGTTTAT
GAACGATTGCTAGAGTTGGGAGTGACAGAAGCAGAGCTGAAAATTGTCTTGCAAGGTATTTGTTACCAACGTCTAATTGC
GAAAGGAGGAATAGTGGATTTTGTCAGTGAAAGGTATCAAGAACACGATCCAAGCGAATGGAATAGGCAAATTGATCAAC
TTTATGCAGCAGGACATATCAATCTTGAACAGGCAAAAGCGGAAAAAATTATCCACAGTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

80.645

99.042

0.799
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

75.08

100

0.751
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

74.76

100

0.748
  comGA/cglA/cilD Streptococcus pneumoniae D39

74.76

100

0.748
  comGA/cglA/cilD Streptococcus pneumoniae R6

74.76

100

0.748
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

74.76

100

0.748
  comYA Streptococcus mutans UA159

65.595

99.361

0.652
  comYA Streptococcus mutans UA140

65.595

99.361

0.652
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

63.226

99.042

0.626
  comGA Lactococcus lactis subsp. cremoris KW2

54.341

99.361

0.54
  comGA Latilactobacillus sakei subsp. sakei 23K

43.678

83.387

0.364

Multiple sequence alignment