Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   A6J72_RS06565 Genome accession   NZ_CP020433
Coordinates   1308642..1309664 (+) Length   340 a.a.
NCBI ID   WP_192573659.1    Uniprot ID   -
Organism   Streptococcus intermedius strain FDAARGOS_233     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1303642..1314664
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J72_RS06535 (A6J72_06545) - 1303897..1304577 (+) 681 WP_003075761.1 CHAP domain-containing protein -
  A6J72_RS06540 (A6J72_06550) - 1304752..1305282 (+) 531 WP_003073971.1 aromatic acid exporter family protein -
  A6J72_RS06545 (A6J72_06555) - 1305359..1305718 (+) 360 WP_003073972.1 MerR family transcriptional regulator -
  A6J72_RS06550 (A6J72_06560) glnA 1305757..1307103 (+) 1347 WP_082312039.1 type I glutamate--ammonia ligase -
  A6J72_RS06555 (A6J72_06565) - 1307325..1307690 (+) 366 WP_003075933.1 DUF1033 family protein -
  A6J72_RS06560 (A6J72_06570) comYA 1307759..1308700 (+) 942 WP_003073980.1 competence type IV pilus ATPase ComGA Machinery gene
  A6J72_RS06565 (A6J72_06575) comYB 1308642..1309664 (+) 1023 WP_192573659.1 competence type IV pilus assembly protein ComGB Machinery gene
  A6J72_RS06570 (A6J72_06580) comYC 1309661..1309978 (+) 318 WP_082312041.1 competence type IV pilus major pilin ComGC Machinery gene
  A6J72_RS06575 (A6J72_06585) comYD 1309938..1310366 (+) 429 WP_037582814.1 competence type IV pilus minor pilin ComGD Machinery gene
  A6J72_RS06580 (A6J72_06590) comGE/cglE 1310338..1310631 (+) 294 WP_003073987.1 competence type IV pilus minor pilin ComGE Machinery gene
  A6J72_RS06585 (A6J72_06595) comGF/cglF 1310615..1311052 (+) 438 WP_003073990.1 competence type IV pilus minor pilin ComGF Machinery gene
  A6J72_RS06590 (A6J72_06600) comGG 1311033..1311359 (+) 327 WP_263969846.1 competence type IV pilus minor pilin ComGG -
  A6J72_RS06595 (A6J72_06605) comYH 1311450..1312403 (+) 954 WP_105255939.1 class I SAM-dependent methyltransferase Machinery gene
  A6J72_RS06600 (A6J72_06610) - 1312450..1313649 (+) 1200 WP_021003254.1 acetate kinase -

Sequence

Protein


Download         Length: 340 a.a.        Molecular weight: 39214.36 Da        Isoelectric Point: 9.7483

>NTDB_id=223010 A6J72_RS06565 WP_192573659.1 1308642..1309664(+) (comYB) [Streptococcus intermedius strain FDAARGOS_233]
MQQDISILNRQKRKKLSTVKQKKVVELLNNLFSSGFHLAEIIDFLKRSALLEKAYVEKMKEGLATGKPFSDIMASLGFSD
NVVTQLSLAELHGNLSLSLSKIEEYLENISKVKKKLIEVATYPFILFIFLVFIMLGLRNYLLPQLESQNIATQLISRLPQ
IFLSSVGVVFALFAIGFYWFRKNSQIRVFSLLSRLPFWGTFVQTYLTAYYAREWGNMIGQGLELSQIFQMMQGQRSAMFQ
EIGKDLEVALQNGQEFSQVVKHYPFFKKELGLMIEYGEVKSKLGCELEVYAQKTWEVFFKRVHQAMNIIQPLVFVFVALM
IVLLYAAMLLPIYQNMEVQL

Nucleotide


Download         Length: 1023 bp        

>NTDB_id=223010 A6J72_RS06565 WP_192573659.1 1308642..1309664(+) (comYB) [Streptococcus intermedius strain FDAARGOS_233]
ATGCAGCAGGACATATCAATCTTGAACAGGCAAAAGCGGAAAAAATTATCCACAGTTAAGCAGAAAAAAGTCGTAGAGTT
ACTAAATAATCTTTTTTCTAGTGGTTTTCACTTGGCAGAAATTATTGATTTTTTGAAACGGAGTGCTTTGTTAGAAAAAG
CCTATGTGGAAAAGATGAAAGAGGGTTTGGCAACTGGAAAGCCTTTTTCAGACATCATGGCAAGTTTAGGTTTTTCGGAT
AATGTAGTAACACAGCTTTCATTGGCGGAATTGCATGGAAATTTATCGCTCAGTTTGAGTAAAATTGAAGAGTATTTGGA
AAATATCTCAAAAGTCAAGAAAAAGTTAATTGAAGTGGCGACTTATCCATTTATTTTATTCATTTTTCTAGTGTTTATTA
TGTTAGGATTGCGCAATTATTTGTTACCGCAGTTGGAGAGTCAGAATATTGCAACACAACTGATTAGTCGTTTACCACAA
ATTTTTCTGAGTTCAGTAGGAGTTGTTTTTGCTTTGTTTGCGATCGGTTTTTATTGGTTTAGAAAAAACTCACAAATAAG
AGTATTTAGTTTGTTGTCTCGTCTTCCTTTTTGGGGCACTTTTGTTCAAACTTATTTGACAGCTTATTATGCGAGAGAAT
GGGGGAATATGATTGGTCAAGGCTTAGAACTCAGTCAGATTTTCCAGATGATGCAAGGACAGCGCTCTGCTATGTTTCAA
GAAATTGGAAAAGATTTAGAAGTAGCACTGCAAAATGGTCAGGAATTTTCACAAGTAGTTAAACATTATCCATTTTTTAA
AAAAGAATTGGGCTTGATGATTGAATATGGGGAAGTGAAATCCAAATTGGGGTGCGAATTAGAGGTTTATGCTCAAAAAA
CGTGGGAGGTATTTTTTAAACGTGTTCATCAAGCGATGAATATCATTCAGCCATTAGTATTTGTCTTTGTGGCGTTGATG
ATTGTATTGTTGTATGCAGCCATGTTGCTGCCAATTTATCAAAATATGGAGGTTCAATTGTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(211-331)

Type II secretion system (T2SS), protein F (T2SSF)

(26-143)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

73.529

100

0.735
  comGB/cglB Streptococcus mitis NCTC 12261

68.955

98.529

0.679
  comGB/cglB Streptococcus mitis SK321

68.657

98.529

0.676
  comGB/cglB Streptococcus pneumoniae TIGR4

67.761

98.529

0.668
  comGB/cglB Streptococcus pneumoniae R6

67.761

98.529

0.668
  comGB/cglB Streptococcus pneumoniae Rx1

67.761

98.529

0.668
  comGB/cglB Streptococcus pneumoniae D39

67.761

98.529

0.668
  comYB Streptococcus mutans UA159

60.819

100

0.612
  comYB Streptococcus mutans UA140

60.819

100

0.612
  comGB Lactococcus lactis subsp. cremoris KW2

52.226

99.118

0.518

Multiple sequence alignment