Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   A6J72_RS06580 Genome accession   NZ_CP020433
Coordinates   1310338..1310631 (+) Length   97 a.a.
NCBI ID   WP_003073987.1    Uniprot ID   -
Organism   Streptococcus intermedius strain FDAARGOS_233     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1305338..1315631
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J72_RS06545 (A6J72_06555) - 1305359..1305718 (+) 360 WP_003073972.1 MerR family transcriptional regulator -
  A6J72_RS06550 (A6J72_06560) glnA 1305757..1307103 (+) 1347 WP_082312039.1 type I glutamate--ammonia ligase -
  A6J72_RS06555 (A6J72_06565) - 1307325..1307690 (+) 366 WP_003075933.1 DUF1033 family protein -
  A6J72_RS06560 (A6J72_06570) comYA 1307759..1308700 (+) 942 WP_003073980.1 competence type IV pilus ATPase ComGA Machinery gene
  A6J72_RS06565 (A6J72_06575) comYB 1308642..1309664 (+) 1023 WP_192573659.1 competence type IV pilus assembly protein ComGB Machinery gene
  A6J72_RS06570 (A6J72_06580) comYC 1309661..1309978 (+) 318 WP_082312041.1 competence type IV pilus major pilin ComGC Machinery gene
  A6J72_RS06575 (A6J72_06585) comYD 1309938..1310366 (+) 429 WP_037582814.1 competence type IV pilus minor pilin ComGD Machinery gene
  A6J72_RS06580 (A6J72_06590) comGE/cglE 1310338..1310631 (+) 294 WP_003073987.1 competence type IV pilus minor pilin ComGE Machinery gene
  A6J72_RS06585 (A6J72_06595) comGF/cglF 1310615..1311052 (+) 438 WP_003073990.1 competence type IV pilus minor pilin ComGF Machinery gene
  A6J72_RS06590 (A6J72_06600) comGG 1311033..1311359 (+) 327 WP_263969846.1 competence type IV pilus minor pilin ComGG -
  A6J72_RS06595 (A6J72_06605) comYH 1311450..1312403 (+) 954 WP_105255939.1 class I SAM-dependent methyltransferase Machinery gene
  A6J72_RS06600 (A6J72_06610) - 1312450..1313649 (+) 1200 WP_021003254.1 acetate kinase -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 11195.24 Da        Isoelectric Point: 10.4670

>NTDB_id=223013 A6J72_RS06580 WP_003073987.1 1310338..1310631(+) (comGE/cglE) [Streptococcus intermedius strain FDAARGOS_233]
MENLRKQYVRGTILLEALLALAIFATIVTLLLGQIHQSRKLENELLKKEEVLRVAKMALQTNQRHLTMNGIEVRVEKSQQ
DIRVYHGKELIFGVQSK

Nucleotide


Download         Length: 294 bp        

>NTDB_id=223013 A6J72_RS06580 WP_003073987.1 1310338..1310631(+) (comGE/cglE) [Streptococcus intermedius strain FDAARGOS_233]
ATGGAAAATTTAAGAAAACAATATGTTAGAGGGACAATTTTATTAGAAGCACTGCTTGCGTTAGCTATTTTTGCGACAAT
TGTGACCCTGTTGTTGGGACAAATTCACCAGTCTCGAAAACTAGAAAATGAGTTATTGAAAAAAGAAGAAGTCTTAAGGG
TAGCGAAGATGGCCTTGCAAACAAATCAAAGGCATTTAACAATGAACGGTATTGAAGTACGTGTCGAAAAAAGCCAACAA
GATATTCGGGTTTATCATGGGAAGGAGCTGATTTTTGGTGTTCAAAGCAAATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(13-91)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

56.522

94.845

0.536
  comGE/cglE Streptococcus pneumoniae D39

56.522

94.845

0.536
  comGE/cglE Streptococcus pneumoniae R6

56.522

94.845

0.536
  comGE/cglE Streptococcus pneumoniae TIGR4

56.522

94.845

0.536
  comGE/cglE Streptococcus mitis NCTC 12261

55.435

94.845

0.526
  comGE/cglE Streptococcus mitis SK321

55.435

94.845

0.526
  comYE Streptococcus mutans UA140

48.352

93.814

0.454
  comYE Streptococcus mutans UA159

48.352

93.814

0.454

Multiple sequence alignment