Detailed information NTG0223014

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: A6J72_RS06585
• Genome accession: NZ_CP020433
• Coordinates: 1310615..1311052 (+)
• Length: 145 a.a.
• NCBI ID: WP_003073990.1
• Uniprot ID: -
• Organism: Streptococcus intermedius strain FDAARGOS_233
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1305615..1316052

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6J72_RS06550 (A6J72_06560)	glnA	1305757..1307103 (+)	1347	WP_082312039.1	type I glutamate--ammonia ligase	-
A6J72_RS06555 (A6J72_06565)	-	1307325..1307690 (+)	366	WP_003075933.1	DUF1033 family protein	-
A6J72_RS06560 (A6J72_06570)	comYA	1307759..1308700 (+)	942	WP_003073980.1	competence type IV pilus ATPase ComGA	Machinery gene
A6J72_RS06565 (A6J72_06575)	comYB	1308642..1309664 (+)	1023	WP_192573659.1	competence type IV pilus assembly protein ComGB	Machinery gene
A6J72_RS06570 (A6J72_06580)	comYC	1309661..1309978 (+)	318	WP_082312041.1	competence type IV pilus major pilin ComGC	Machinery gene
A6J72_RS06575 (A6J72_06585)	comYD	1309938..1310366 (+)	429	WP_037582814.1	competence type IV pilus minor pilin ComGD	Machinery gene
A6J72_RS06580 (A6J72_06590)	comGE/cglE	1310338..1310631 (+)	294	WP_003073987.1	competence type IV pilus minor pilin ComGE	Machinery gene
A6J72_RS06585 (A6J72_06595)	comGF/cglF	1310615..1311052 (+)	438	WP_003073990.1	competence type IV pilus minor pilin ComGF	Machinery gene
A6J72_RS06590 (A6J72_06600)	comGG	1311033..1311359 (+)	327	WP_263969846.1	competence type IV pilus minor pilin ComGG	-
A6J72_RS06595 (A6J72_06605)	comYH	1311450..1312403 (+)	954	WP_105255939.1	class I SAM-dependent methyltransferase	Machinery gene
A6J72_RS06600 (A6J72_06610)	-	1312450..1313649 (+)	1200	WP_021003254.1	acetate kinase	-
A6J72_RS06605 (A6J72_06615)	glmS	1314039..1315853 (+)	1815	WP_082312042.1	glutamine--fructose-6-phosphate transaminase (isomerizing)	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16858.51 Da
• Isoelectric Point: 10.2149

>NTDB_id=223014 A6J72_RS06585 WP_003073990.1 1310615..1311052(+) (comGF/cglF) [Streptococcus intermedius strain FDAARGOS_233]
MFKANKVKAFTLLEALIALFVLSGSVLLFQSMTRLLASEVQTRQHSEQREWLLFADQLEVELTRSSFEKVENNRLYMKQD
GKVIAFGKASGQDFRKTNANGKGYQPMVYDVKKAEISQENELVRIRLLFKRGLEREFIYRVETKS

Nucleotide

• Length: 438 bp

>NTDB_id=223014 A6J72_RS06585 WP_003073990.1 1310615..1311052(+) (comGF/cglF) [Streptococcus intermedius strain FDAARGOS_233]
GTGTTCAAAGCAAATAAAGTAAAAGCTTTTACACTTTTAGAGGCTCTGATTGCCCTATTCGTACTCAGTGGAAGTGTATT
GCTATTTCAATCTATGACGCGTCTTCTGGCTTCTGAAGTCCAAACTCGACAACACAGTGAACAGCGAGAATGGCTTTTGT
TTGCCGATCAACTAGAAGTGGAGTTGACGCGTTCTTCATTTGAAAAAGTGGAGAATAATCGTTTATACATGAAGCAAGAT
GGTAAGGTAATTGCATTTGGAAAAGCAAGTGGACAAGATTTCAGGAAAACCAATGCGAATGGGAAAGGTTATCAGCCCAT
GGTTTATGATGTGAAAAAAGCAGAAATTTCACAGGAAAATGAGCTAGTTCGTATTCGATTACTGTTTAAGAGAGGATTGG
AAAGGGAATTCATCTATCGTGTGGAAACAAAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (38-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae R6	68.571	96.552	0.662
comGF/cglF	Streptococcus pneumoniae TIGR4	68.571	96.552	0.662
comGF/cglF	Streptococcus pneumoniae Rx1	68.571	96.552	0.662
comGF/cglF	Streptococcus pneumoniae D39	68.571	96.552	0.662
comGF/cglF	Streptococcus mitis NCTC 12261	67.857	96.552	0.655
comGF/cglF	Streptococcus mitis SK321	67.857	96.552	0.655
comYF	Streptococcus mutans UA159	41.135	97.241	0.4
comYF	Streptococcus mutans UA140	41.135	97.241	0.4
comGF	Lactococcus lactis subsp. cremoris KW2	42.963	93.103	0.4