Detailed information NTG0223012

Bioinformatically predicted

Overview

• Name: comYD
• Type: Machinery gene
• Locus tag: A6J72_RS06575
• Genome accession: NZ_CP020433
• Coordinates: 1309938..1310366 (+)
• Length: 142 a.a.
• NCBI ID: WP_037582814.1
• Uniprot ID: A0A428ENI2
• Organism: Streptococcus intermedius strain FDAARGOS_233
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1304938..1315366

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6J72_RS06545 (A6J72_06555)	-	1305359..1305718 (+)	360	WP_003073972.1	MerR family transcriptional regulator	-
A6J72_RS06550 (A6J72_06560)	glnA	1305757..1307103 (+)	1347	WP_082312039.1	type I glutamate--ammonia ligase	-
A6J72_RS06555 (A6J72_06565)	-	1307325..1307690 (+)	366	WP_003075933.1	DUF1033 family protein	-
A6J72_RS06560 (A6J72_06570)	comYA	1307759..1308700 (+)	942	WP_003073980.1	competence type IV pilus ATPase ComGA	Machinery gene
A6J72_RS06565 (A6J72_06575)	comYB	1308642..1309664 (+)	1023	WP_192573659.1	competence type IV pilus assembly protein ComGB	Machinery gene
A6J72_RS06570 (A6J72_06580)	comYC	1309661..1309978 (+)	318	WP_082312041.1	competence type IV pilus major pilin ComGC	Machinery gene
A6J72_RS06575 (A6J72_06585)	comYD	1309938..1310366 (+)	429	WP_037582814.1	competence type IV pilus minor pilin ComGD	Machinery gene
A6J72_RS06580 (A6J72_06590)	comGE/cglE	1310338..1310631 (+)	294	WP_003073987.1	competence type IV pilus minor pilin ComGE	Machinery gene
A6J72_RS06585 (A6J72_06595)	comGF/cglF	1310615..1311052 (+)	438	WP_003073990.1	competence type IV pilus minor pilin ComGF	Machinery gene
A6J72_RS06590 (A6J72_06600)	comGG	1311033..1311359 (+)	327	WP_263969846.1	competence type IV pilus minor pilin ComGG	-
A6J72_RS06595 (A6J72_06605)	comYH	1311450..1312403 (+)	954	WP_105255939.1	class I SAM-dependent methyltransferase	Machinery gene
A6J72_RS06600 (A6J72_06610)	-	1312450..1313649 (+)	1200	WP_021003254.1	acetate kinase	-

Sequence

Protein

• Length: 142 a.a.
• Molecular weight: 16304.83 Da
• Isoelectric Point: 10.3161

>NTDB_id=223012 A6J72_RS06575 WP_037582814.1 1309938..1310366(+) (comYD) [Streptococcus intermedius strain FDAARGOS_233]
MRNIQKKLVLLQIKGFTILESLLTLFVASFLLLAVSGAVRSSFEQVEEQIFFLEFEHFYRESQKLSNATQRQLDMNFSRE
RISNGYNSLSIPRSVHAPDDLTLRFDKAGGNSSLGKIVFQTKRQTITYQLYLGNGKFKKTIC

Nucleotide

• Length: 429 bp

>NTDB_id=223012 A6J72_RS06575 WP_037582814.1 1309938..1310366(+) (comYD) [Streptococcus intermedius strain FDAARGOS_233]
ATGCGAAACATACAAAAGAAACTCGTTCTGTTGCAGATTAAGGGATTTACAATTTTGGAAAGTTTGCTGACTTTGTTTGT
AGCGAGTTTTTTATTACTTGCTGTTTCAGGGGCTGTCCGTTCCTCTTTTGAACAAGTGGAAGAGCAGATTTTCTTTCTTG
AGTTTGAGCATTTTTACCGAGAAAGCCAGAAGTTGAGTAATGCTACTCAAAGGCAATTGGACATGAATTTTTCTCGTGAG
CGAATTTCTAATGGGTACAATTCTTTATCAATTCCTCGCTCGGTTCACGCTCCAGATGATTTAACACTTCGTTTTGATAA
GGCAGGTGGTAATTCCTCGCTTGGTAAGATTGTATTTCAGACGAAAAGACAGACAATTACGTATCAATTATATCTAGGAA
ATGGAAAATTTAAGAAAACAATATGTTAG

Domains

No domain identified.

3D structure

• AlphaFold DB: A0A428ENI2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYD	Streptococcus gordonii str. Challis substr. CH1	60.769	91.549	0.556
comGD/cglD	Streptococcus mitis NCTC 12261	55.039	90.845	0.5
comGD/cglD	Streptococcus mitis SK321	54.331	89.437	0.486
comGD/cglD	Streptococcus pneumoniae Rx1	54.331	89.437	0.486
comGD/cglD	Streptococcus pneumoniae D39	54.331	89.437	0.486
comGD/cglD	Streptococcus pneumoniae R6	54.331	89.437	0.486
comGD/cglD	Streptococcus pneumoniae TIGR4	53.543	89.437	0.479
comYD	Streptococcus mutans UA140	50.769	91.549	0.465
comYD	Streptococcus mutans UA159	50.769	91.549	0.465