Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX/comX1/sigX1   Type   Regulator
Locus tag   RN80_RS00965 Genome accession   NZ_CP012646
Coordinates   170970..171449 (-) Length   159 a.a.
NCBI ID   WP_060627198.1    Uniprot ID   -
Organism   Streptococcus mitis strain KCOM 1350 (= ChDC B183)     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 165970..176449
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RN80_RS00965 (RN80_00975) comX/sigX/comX1/sigX1 170970..171449 (-) 480 WP_060627198.1 transcriptional regulator Regulator
  RN80_RS00970 (RN80_00980) nusG 171569..172105 (-) 537 WP_049486629.1 transcription termination/antitermination protein NusG -
  RN80_RS00975 (RN80_00985) secE 172159..172335 (-) 177 WP_001210991.1 preprotein translocase subunit SecE -
  RN80_RS00980 (RN80_00990) rpmG 172345..172497 (-) 153 WP_001809375.1 50S ribosomal protein L33 -
  RN80_RS00985 (RN80_00995) pbp2a 172550..174745 (-) 2196 WP_060627199.1 penicillin-binding protein PBP2A -
  RN80_RS00990 (RN80_01000) - 174832..175707 (+) 876 WP_080998465.1 RluA family pseudouridine synthase -

Sequence

Protein


Download         Length: 159 a.a.        Molecular weight: 19918.71 Da        Isoelectric Point: 8.6065

>NTDB_id=155973 RN80_RS00965 WP_060627198.1 170970..171449(-) (comX/sigX/comX1/sigX1) [Streptococcus mitis strain KCOM 1350 (= ChDC B183)]
MLKELYEKVQGIVYKCRNEYYLHLWELSDWDQEGMICLHELISREEGIIEDIPRLRRYFKTKFRNRILDYIRKQESQKRR
YDKEPYEEVGELSHRISEGGLCLDDYYLFHETLRDYRSKQSKDKQEELERVLRNERFRGRQRVLRDLRIVFKEFDIRTR

Nucleotide


Download         Length: 480 bp        

>NTDB_id=155973 RN80_RS00965 WP_060627198.1 170970..171449(-) (comX/sigX/comX1/sigX1) [Streptococcus mitis strain KCOM 1350 (= ChDC B183)]
ATGCTTAAAGAATTGTATGAAAAAGTCCAAGGGATTGTATATAAGTGTAGAAATGAATATTACTTGCATTTATGGGAGTT
ATCTGATTGGGACCAAGAGGGGATGATTTGCTTACATGAATTGATTAGTAGAGAAGAAGGAATAATAGAAGATATTCCTC
GTTTAAGGAGATATTTTAAGACTAAGTTCCGGAATCGAATTCTAGACTATATCCGTAAGCAAGAAAGTCAAAAACGAAGA
TATGATAAAGAACCCTATGAAGAAGTAGGTGAGCTTAGTCATCGTATCAGTGAGGGAGGTCTGTGTCTAGATGATTATTA
TCTCTTTCATGAGACACTAAGAGATTATAGAAGCAAACAAAGTAAAGACAAACAAGAAGAGTTAGAACGCGTCTTAAGAA
ATGAACGCTTCCGAGGGCGTCAAAGAGTATTAAGAGACTTACGTATTGTGTTTAAAGAGTTTGACATCCGTACTCGGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

93.038

99.371

0.925
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

91.195

100

0.912
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

91.772

99.371

0.912
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

90.566

100

0.906
  comX/comX2 Streptococcus pneumoniae R6

91.139

99.371

0.906
  comX/comX2 Streptococcus pneumoniae Rx1

91.139

99.371

0.906
  comX/comX1 Streptococcus pneumoniae R6

91.139

99.371

0.906
  comX/comX1 Streptococcus pneumoniae Rx1

91.139

99.371

0.906
  comX/comX2 Streptococcus pneumoniae D39

91.139

99.371

0.906
  comX/comX1 Streptococcus pneumoniae D39

91.139

99.371

0.906
  comX/comX1 Streptococcus pneumoniae TIGR4

90.506

99.371

0.899
  comX/comX2 Streptococcus pneumoniae TIGR4

90.506

99.371

0.899
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

48.718

98.113

0.478
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

48.718

98.113

0.478
  comX/sigX Streptococcus mutans UA159

45.333

94.34

0.428
  comX/sigX Streptococcus suis D9

44.444

96.226

0.428
  comX/sigX Streptococcus suis isolate S10

44.444

96.226

0.428
  comX/sigX Streptococcus suis P1/7

44.444

96.226

0.428
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

42.953

93.711

0.403
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

42.953

93.711

0.403
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

42.953

93.711

0.403
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

42.953

93.711

0.403
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

42.105

95.597

0.403
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

42.105

95.597

0.403
  comX Streptococcus thermophilus LMG 18311

38.667

94.34

0.365
  comX Streptococcus thermophilus LMD-9

38.667

94.34

0.365

Multiple sequence alignment