Detailed information NTG0125680

Bioinformatically predicted

Overview

• Name: comYC
• Type: Machinery gene
• Locus tag: ID09_RS00685
• Genome accession: NZ_CP008921
• Coordinates: 104013..104294 (+)
• Length: 93 a.a.
• NCBI ID: WP_024382124.1
• Uniprot ID: A0A075SBB9
• Organism: Streptococcus suis 6407
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 99013..109294

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ID09_RS00665 (ID09_00680)	-	100676..101041 (+)	366	WP_002936568.1	DUF1033 family protein	-
ID09_RS00670 (ID09_00685)	-	101076..102026 (-)	951	WP_024382126.1	S66 peptidase family protein	-
ID09_RS00675 (ID09_00690)	comYA	102112..103062 (+)	951	WP_024382125.1	competence type IV pilus ATPase ComGA	Machinery gene
ID09_RS00680 (ID09_00695)	comYB	102974..104011 (+)	1038	WP_255195823.1	competence type IV pilus assembly protein ComGB	Machinery gene
ID09_RS00685 (ID09_00700)	comYC	104013..104294 (+)	282	WP_024382124.1	competence type IV pilus major pilin ComGC	Machinery gene
ID09_RS00690 (ID09_00705)	comGD	104275..104682 (+)	408	WP_024382123.1	competence type IV pilus minor pilin ComGD	-
ID09_RS00695 (ID09_00710)	comYE	104654..104947 (+)	294	WP_024382122.1	competence type IV pilus minor pilin ComGE	Machinery gene
ID09_RS00700 (ID09_00715)	comGF/cglF	104934..105368 (+)	435	WP_024382121.1	competence type IV pilus minor pilin ComGF	Machinery gene
ID09_RS00705 (ID09_00720)	comGG	105346..105756 (+)	411	WP_024382120.1	competence type IV pilus minor pilin ComGG	-
ID09_RS00710 (ID09_00725)	comYH	105813..106766 (+)	954	WP_024382119.1	class I SAM-dependent methyltransferase	Machinery gene
ID09_RS00715 (ID09_00730)	-	106816..108003 (+)	1188	WP_038425630.1	acetate kinase	-
ID09_RS00720 (ID09_00735)	-	108318..108869 (+)	552	WP_024382117.1	folate family ECF transporter S component	-

Sequence

Protein

• Length: 93 a.a.
• Molecular weight: 10377.37 Da
• Isoelectric Point: 9.3901

>NTDB_id=125680 ID09_RS00685 WP_024382124.1 104013..104294(+) (comYC) [Streptococcus suis 6407]
MKKLVEMKVKGFTLVEMLVVLGIISLLLLLFVPNLSQQKDAIQKKGDAAVVKVVESQMELYELEHDKEATVADLQAAGYI
TEKQAKQYAKAKK

Nucleotide

• Length: 282 bp

>NTDB_id=125680 ID09_RS00685 WP_024382124.1 104013..104294(+) (comYC) [Streptococcus suis 6407]
ATGAAAAAATTAGTTGAAATGAAGGTAAAAGGGTTCACTCTGGTGGAAATGTTAGTCGTTTTGGGGATCATTAGCCTGCT
CTTGCTCCTTTTTGTGCCAAATTTGAGCCAGCAGAAGGATGCTATTCAGAAGAAGGGGGATGCGGCTGTTGTCAAAGTAG
TGGAGAGCCAGATGGAGCTCTATGAATTGGAACATGACAAGGAAGCAACGGTGGCAGACTTGCAGGCAGCTGGCTACATC
ACTGAAAAACAAGCAAAACAGTATGCTAAGGCGAAGAAATAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (8-30)

3D structure

• AlphaFold DB: A0A075SBB9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYC	Streptococcus suis isolate S10	96.774	100	0.968
comGC/cglC	Streptococcus mitis SK321	67.059	91.398	0.613
comGC/cglC	Streptococcus mitis NCTC 12261	67.059	91.398	0.613
comGC/cglC	Streptococcus pneumoniae D39	69.136	87.097	0.602
comGC/cglC	Streptococcus pneumoniae R6	69.136	87.097	0.602
comGC/cglC	Streptococcus pneumoniae TIGR4	69.136	87.097	0.602
comGC/cglC	Streptococcus pneumoniae Rx1	69.136	87.097	0.602
comYC	Streptococcus gordonii str. Challis substr. CH1	62.921	95.699	0.602
comYC	Streptococcus mutans UA140	60.227	94.624	0.57
comYC	Streptococcus mutans UA159	60.227	94.624	0.57
comGC	Lactococcus lactis subsp. cremoris KW2	57.955	94.624	0.548
comGC	Staphylococcus aureus N315	50	83.871	0.419
comGC	Staphylococcus aureus MW2	50	83.871	0.419
comGC	Latilactobacillus sakei subsp. sakei 23K	44.706	91.398	0.409
comGC	Bacillus subtilis subsp. subtilis str. 168	49.333	80.645	0.398