Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   ID09_RS00675 Genome accession   NZ_CP008921
Coordinates   102112..103062 (+) Length   316 a.a.
NCBI ID   WP_024382125.1    Uniprot ID   A0A075SNN5
Organism   Streptococcus suis 6407     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 97112..108062
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ID09_RS00665 (ID09_00680) - 100676..101041 (+) 366 WP_002936568.1 DUF1033 family protein -
  ID09_RS00670 (ID09_00685) - 101076..102026 (-) 951 WP_024382126.1 S66 peptidase family protein -
  ID09_RS00675 (ID09_00690) comYA 102112..103062 (+) 951 WP_024382125.1 competence type IV pilus ATPase ComGA Machinery gene
  ID09_RS00680 (ID09_00695) comYB 102974..104011 (+) 1038 WP_255195823.1 competence type IV pilus assembly protein ComGB Machinery gene
  ID09_RS00685 (ID09_00700) comYC 104013..104294 (+) 282 WP_024382124.1 competence type IV pilus major pilin ComGC Machinery gene
  ID09_RS00690 (ID09_00705) comGD 104275..104682 (+) 408 WP_024382123.1 competence type IV pilus minor pilin ComGD -
  ID09_RS00695 (ID09_00710) comYE 104654..104947 (+) 294 WP_024382122.1 competence type IV pilus minor pilin ComGE Machinery gene
  ID09_RS00700 (ID09_00715) comGF/cglF 104934..105368 (+) 435 WP_024382121.1 competence type IV pilus minor pilin ComGF Machinery gene
  ID09_RS00705 (ID09_00720) comGG 105346..105756 (+) 411 WP_024382120.1 competence type IV pilus minor pilin ComGG -
  ID09_RS00710 (ID09_00725) comYH 105813..106766 (+) 954 WP_024382119.1 class I SAM-dependent methyltransferase Machinery gene
  ID09_RS00715 (ID09_00730) - 106816..108003 (+) 1188 WP_038425630.1 acetate kinase -

Sequence

Protein


Download         Length: 316 a.a.        Molecular weight: 35384.31 Da        Isoelectric Point: 5.6934

>NTDB_id=125678 ID09_RS00675 WP_024382125.1 102112..103062(+) (comYA) [Streptococcus suis 6407]
MIQEKARKMIEEAVADRVSDIYLVPRGECYQVYHRIMDEREFVQDMAEEEVIAIISHFKFLAGLNVGEKRRSQQGSCDYD
YGSGEISLRLSTVGDYRGKESLVIRLLYDNDKELKFWFEAAERLAEEIKGRGLYLFSGPVGSGKTTLMYHLARLKFPDKQ
ILTIEDPVEIKQDGMLQLQLNEAIGATYDNLIKLSLRHRPDLLIIGEIRDAETARAVIRASLTGATVFSTVHARSISGVY
ARMLELGVSPEELNNALQGIAYQRLIGGGGVVDFAKGNYQNHSADQWNAQIDRLFAAGHISLRQAETEKIALGSPA

Nucleotide


Download         Length: 951 bp        

>NTDB_id=125678 ID09_RS00675 WP_024382125.1 102112..103062(+) (comYA) [Streptococcus suis 6407]
ATGATTCAAGAAAAAGCAAGAAAGATGATTGAAGAGGCGGTGGCAGATAGGGTCAGTGACATCTATCTAGTTCCTCGAGG
TGAGTGTTACCAAGTCTATCATCGTATCATGGACGAGCGGGAATTTGTGCAAGACATGGCTGAGGAGGAAGTAATAGCCA
TCATTAGCCATTTCAAGTTTTTAGCAGGTTTAAATGTTGGTGAAAAACGCCGTAGCCAGCAGGGTTCCTGTGACTATGAT
TATGGGAGCGGAGAGATTTCGCTTCGCTTATCAACTGTCGGTGATTATCGTGGCAAGGAAAGTTTGGTTATCCGCCTGCT
CTATGACAATGACAAGGAACTCAAGTTCTGGTTTGAGGCGGCCGAGCGGCTTGCAGAAGAAATCAAGGGACGAGGGCTCT
ACCTTTTTTCGGGTCCGGTCGGCTCTGGTAAGACCACACTTATGTACCATCTTGCCAGGCTGAAGTTTCCAGACAAGCAA
ATTTTGACCATTGAAGATCCTGTAGAAATCAAGCAGGACGGGATGTTGCAGCTCCAGCTCAATGAAGCCATCGGAGCCAC
CTACGACAATCTGATCAAACTGTCCCTCCGTCATCGACCAGACTTGCTCATCATCGGTGAAATTCGGGATGCGGAAACCG
CTCGAGCAGTCATTCGAGCCAGCCTGACAGGAGCTACCGTTTTCTCAACGGTTCATGCAAGGTCTATTTCGGGTGTCTAT
GCTCGTATGTTGGAATTGGGTGTCAGTCCTGAGGAGTTAAACAATGCCCTTCAAGGTATTGCCTATCAACGTTTAATCGG
GGGAGGAGGTGTGGTAGATTTTGCAAAGGGAAATTACCAAAACCATTCCGCAGACCAGTGGAATGCGCAAATTGATCGCC
TTTTTGCAGCAGGACATATCAGTCTTAGGCAGGCAGAAACAGAAAAAATTGCCCTTGGCTCGCCAGCGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A075SNN5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

68.387

98.101

0.671
  comYA Streptococcus mutans UA140

68.167

98.418

0.671
  comYA Streptococcus mutans UA159

68.167

98.418

0.671
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

65.595

98.418

0.646
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

65.273

98.418

0.642
  comGA/cglA/cilD Streptococcus pneumoniae R6

65.273

98.418

0.642
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

65.273

98.418

0.642
  comGA/cglA/cilD Streptococcus pneumoniae D39

65.273

98.418

0.642
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

65.161

98.101

0.639
  comGA Lactococcus lactis subsp. cremoris KW2

52.997

100

0.532

Multiple sequence alignment