Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYE   Type   Machinery gene
Locus tag   ID09_RS00695 Genome accession   NZ_CP008921
Coordinates   104654..104947 (+) Length   97 a.a.
NCBI ID   WP_024382122.1    Uniprot ID   A0A075SE82
Organism   Streptococcus suis 6407     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 99654..109947
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ID09_RS00665 (ID09_00680) - 100676..101041 (+) 366 WP_002936568.1 DUF1033 family protein -
  ID09_RS00670 (ID09_00685) - 101076..102026 (-) 951 WP_024382126.1 S66 peptidase family protein -
  ID09_RS00675 (ID09_00690) comYA 102112..103062 (+) 951 WP_024382125.1 competence type IV pilus ATPase ComGA Machinery gene
  ID09_RS00680 (ID09_00695) comYB 102974..104011 (+) 1038 WP_255195823.1 competence type IV pilus assembly protein ComGB Machinery gene
  ID09_RS00685 (ID09_00700) comYC 104013..104294 (+) 282 WP_024382124.1 competence type IV pilus major pilin ComGC Machinery gene
  ID09_RS00690 (ID09_00705) comGD 104275..104682 (+) 408 WP_024382123.1 competence type IV pilus minor pilin ComGD -
  ID09_RS00695 (ID09_00710) comYE 104654..104947 (+) 294 WP_024382122.1 competence type IV pilus minor pilin ComGE Machinery gene
  ID09_RS00700 (ID09_00715) comGF/cglF 104934..105368 (+) 435 WP_024382121.1 competence type IV pilus minor pilin ComGF Machinery gene
  ID09_RS00705 (ID09_00720) comGG 105346..105756 (+) 411 WP_024382120.1 competence type IV pilus minor pilin ComGG -
  ID09_RS00710 (ID09_00725) comYH 105813..106766 (+) 954 WP_024382119.1 class I SAM-dependent methyltransferase Machinery gene
  ID09_RS00715 (ID09_00730) - 106816..108003 (+) 1188 WP_038425630.1 acetate kinase -
  ID09_RS00720 (ID09_00735) - 108318..108869 (+) 552 WP_024382117.1 folate family ECF transporter S component -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10826.75 Da        Isoelectric Point: 10.2089

>NTDB_id=125681 ID09_RS00695 WP_024382122.1 104654..104947(+) (comYE) [Streptococcus suis 6407]
MVAIRKQKNKAYILLESLVALATLVTICSLILSAVDAGRRRQAWELEQQEVLNLAQMAVQTRQDNLALNGVTVQVQRTAD
KIIVFHEGKEVLSVVKK

Nucleotide


Download         Length: 294 bp        

>NTDB_id=125681 ID09_RS00695 WP_024382122.1 104654..104947(+) (comYE) [Streptococcus suis 6407]
GTGGTCGCTATAAGAAAACAGAAGAATAAGGCTTATATTTTGCTAGAAAGTCTGGTTGCCCTTGCGACTCTAGTGACCAT
TTGCAGCTTGATTTTATCAGCTGTGGATGCTGGTCGCAGGCGACAGGCTTGGGAATTGGAACAACAGGAGGTTCTCAATC
TAGCTCAGATGGCTGTTCAGACCAGGCAAGATAACCTAGCCTTAAACGGTGTTACAGTTCAGGTTCAACGAACAGCGGAT
AAGATCATTGTTTTCCACGAGGGAAAGGAGGTTTTATCGGTTGTTAAAAAGTAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A075SE82

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYE Streptococcus mutans UA140

54.639

100

0.546
  comYE Streptococcus mutans UA159

54.639

100

0.546
  comGE/cglE Streptococcus pneumoniae Rx1

40.217

94.845

0.381
  comGE/cglE Streptococcus pneumoniae D39

40.217

94.845

0.381
  comGE/cglE Streptococcus pneumoniae R6

40.217

94.845

0.381
  comGE/cglE Streptococcus pneumoniae TIGR4

40.217

94.845

0.381
  comGE/cglE Streptococcus mitis SK321

39.13

94.845

0.371
  comGE/cglE Streptococcus mitis NCTC 12261

39.13

94.845

0.371

Multiple sequence alignment