Detailed information    

insolico Bioinformatically predicted

Overview


Name   comX/comX2   Type   Regulator
Locus tag   ACLV7A_RS01225 Genome accession   NZ_OZ217344
Coordinates   234580..235059 (+) Length   159 a.a.
NCBI ID   WP_411863380.1    Uniprot ID   -
Organism   Streptococcus mitis isolate S. mitis E22     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context


Location: 229580..240059
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7A_RS01200 (SMIE22_02330) - 230321..231196 (-) 876 WP_314517496.1 RluA family pseudouridine synthase -
  ACLV7A_RS01205 (SMIE22_02340) pbp2a 231283..233478 (+) 2196 WP_411863378.1 penicillin-binding protein PBP2A -
  ACLV7A_RS01210 rpmG 233531..233683 (+) 153 WP_014017356.1 50S ribosomal protein L33 -
  ACLV7A_RS01215 (SMIE22_02350) secE 233693..233869 (+) 177 WP_001210991.1 preprotein translocase subunit SecE -
  ACLV7A_RS01220 (SMIE22_02360) nusG 233924..234460 (+) 537 WP_411863379.1 transcription termination/antitermination protein NusG -
  ACLV7A_RS01225 (SMIE22_02370) comX/comX2 234580..235059 (+) 480 WP_411863380.1 sigma-70 family RNA polymerase sigma factor Regulator

Sequence


Protein


Download         Length: 159 a.a.        Molecular weight: 19996.67 Da        Isoelectric Point: 7.4296

>NTDB_id=1170261 ACLV7A_RS01225 WP_411863380.1 234580..235059(+) (comX/comX2) [Streptococcus mitis isolate S. mitis E22]
MLKELYEEVQGSVYKCRNEYYLHLWELSDWEQEGMICLHELISREEGLVEDIPRLRKYFKTKFRNRILDYIRKQESHKRR
YNKEPYEEVGEISHRISEGDLWLDDYYLFHETLRDYRSKQSKDKREELERVLRDERFRGRQRVLKDLRIVFKEFDIRTH

Nucleotide


Download         Length: 480 bp        

>NTDB_id=1170261 ACLV7A_RS01225 WP_411863380.1 234580..235059(+) (comX/comX2) [Streptococcus mitis isolate S. mitis E22]
ATGCTTAAAGAATTGTATGAAGAAGTCCAGGGGAGTGTATATAAGTGTAGAAATGAATATTACCTTCATTTATGGGAATT
GTCGGATTGGGAGCAAGAGGGAATGATTTGCTTACATGAATTGATCAGTAGAGAAGAAGGATTGGTAGAAGATATTCCAC
GTTTAAGGAAATATTTCAAAACCAAGTTTCGAAATCGAATTTTAGACTATATCCGTAAGCAAGAAAGCCACAAACGAAGA
TATAATAAAGAACCTTATGAAGAAGTAGGCGAGATCAGTCATCGTATAAGTGAGGGAGATCTGTGGCTAGATGACTATTA
TCTCTTTCATGAAACACTAAGAGATTATAGAAGCAAACAAAGTAAAGACAAACGAGAAGAGCTAGAACGCGTCTTAAGAG
ATGAACGCTTCCGAGGGCGTCAAAGAGTGCTAAAAGACTTACGTATTGTGTTTAAAGAGTTTGACATCCGTACCCATTAG

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/comX2 Streptococcus pneumoniae TIGR4

91.195

100

0.912

  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

91.195

100

0.912

  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

91.195

100

0.912

  comX/comX1 Streptococcus pneumoniae TIGR4

91.195

100

0.912

  comX/comX1 Streptococcus pneumoniae D39

90.566

100

0.906

  comX/comX1 Streptococcus pneumoniae R6

90.566

100

0.906

  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

90.566

100

0.906

  comX/comX2 Streptococcus pneumoniae R6

90.566

100

0.906

  comX/comX2 Streptococcus pneumoniae Rx1

90.566

100

0.906

  comX/comX1 Streptococcus pneumoniae Rx1

90.566

100

0.906

  comX/comX2 Streptococcus pneumoniae D39

90.566

100

0.906

  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

89.241

99.371

0.887

  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

48.718

98.113

0.478

  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

48.718

98.113

0.478

  comX/sigX Streptococcus mutans UA159

44.667

94.34

0.421

  comX/sigX Streptococcus suis D9

42.484

96.226

0.409

  comX/sigX Streptococcus suis isolate S10

42.484

96.226

0.409

  comX/sigX Streptococcus suis P1/7

42.484

96.226

0.409

  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

39.474

95.597

0.377

  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

39.474

95.597

0.377

  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

40.268

93.711

0.377

  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

40.268

93.711

0.377

  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

40.268

93.711

0.377

  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

40.268

93.711

0.377

  comX Streptococcus thermophilus LMG 18311

38.667

94.34

0.365

  comX Streptococcus thermophilus LMD-9

38.667

94.34

0.365


Multiple sequence alignment