Detailed information NTG1145113

Bioinformatically predicted

Overview

• Name: comYC
• Type: Machinery gene
• Locus tag: STACADC2_RS08465
• Genome accession: NZ_LT604076
• Coordinates: 1594321..1594647 (-)
• Length: 108 a.a.
• NCBI ID: WP_002946126.1
• Uniprot ID: A0A0E2Q1B3
• Organism: Streptococcus thermophilus strain ACA-DC
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1589321..1599647

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STACADC2_RS10180 (STACADC2_1630)	-	1589583..1590008 (-)	426	WP_087010196.1	CPBP family intramembrane glutamic endopeptidase	-
STACADC2_RS08430 (STACADC2_1631)	-	1590256..1590453 (-)	198	WP_002885716.1	helix-turn-helix transcriptional regulator	-
STACADC2_RS08435 (STACADC2_1632)	-	1590702..1591895 (-)	1194	WP_087010197.1	acetate kinase	-
STACADC2_RS08440 (STACADC2_1633)	comYH	1591951..1592907 (-)	957	WP_011226622.1	class I SAM-dependent methyltransferase	Machinery gene
STACADC2_RS08445 (STACADC2_1634)	comGG	1592952..1593269 (-)	318	WP_002952035.1	competence type IV pilus minor pilin ComGG	-
STACADC2_RS08450 (STACADC2_1635)	comYF	1593247..1593684 (-)	438	WP_022096897.1	competence type IV pilus minor pilin ComGF	Machinery gene
STACADC2_RS08455 (STACADC2_1636)	comGE	1593668..1593961 (-)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	-
STACADC2_RS08460 (STACADC2_1637)	comYD	1593933..1594361 (-)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
STACADC2_RS08465 (STACADC2_1638)	comYC	1594321..1594647 (-)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
STACADC2_RS08470 (STACADC2_1639)	comYB	1594644..1595744 (-)	1101	WP_157659050.1	competence type IV pilus assembly protein ComGB	Machinery gene
STACADC2_RS08475 (STACADC2_1640)	comGA/cglA/cilD	1595626..1596567 (-)	942	WP_022096896.1	competence type IV pilus ATPase ComGA	Machinery gene
STACADC2_RS08480 (STACADC2_1641)	-	1596648..1597010 (-)	363	WP_087010198.1	DUF1033 family protein	-

Sequence

Protein

• Length: 108 a.a.
• Molecular weight: 11914.00 Da
• Isoelectric Point: 9.9219

>NTDB_id=1145113 STACADC2_RS08465 WP_002946126.1 1594321..1594647(-) (comYC) [Streptococcus thermophilus strain ACA-DC]
MKLMLKKLNAVKLRAFTLIEMLVVLLIISILLLLFVPNLSKQKDSVKETGNAAVVKVVDSQAELYEMKNNKTASLAALVS
EGQITQKQADSYNDYYAKHGGESRSVAN

Nucleotide

• Length: 327 bp

>NTDB_id=1145113 STACADC2_RS08465 WP_002946126.1 1594321..1594647(-) (comYC) [Streptococcus thermophilus strain ACA-DC]
ATGAAATTGATGTTAAAAAAATTGAATGCCGTTAAATTACGAGCCTTTACTCTGATTGAAATGCTAGTAGTACTTCTCAT
TATCAGTATTCTCCTTTTGCTCTTTGTTCCTAACTTAAGCAAGCAGAAGGATTCCGTTAAGGAAACTGGAAATGCGGCTG
TAGTCAAGGTCGTGGATTCTCAGGCAGAACTTTATGAAATGAAGAATAACAAGACAGCTAGCTTGGCAGCTCTTGTTTCA
GAAGGTCAAATTACGCAAAAACAGGCAGATTCATACAATGATTACTATGCGAAACATGGTGGTGAAAGCCGCTCAGTGGC
CAATTAG

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (14-34)

3D structure

• AlphaFold DB: A0A0E2Q1B3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYC	Streptococcus mutans UA140	69.231	96.296	0.667
comYC	Streptococcus mutans UA159	69.231	96.296	0.667
comYC	Streptococcus gordonii str. Challis substr. CH1	63.81	97.222	0.62
comGC/cglC	Streptococcus mitis SK321	62.264	98.148	0.611
comGC/cglC	Streptococcus mitis NCTC 12261	58.333	100	0.583
comGC/cglC	Streptococcus pneumoniae D39	58.491	98.148	0.574
comGC/cglC	Streptococcus pneumoniae R6	58.491	98.148	0.574
comGC/cglC	Streptococcus pneumoniae Rx1	58.491	98.148	0.574
comGC/cglC	Streptococcus pneumoniae TIGR4	58.491	98.148	0.574
comGC	Lactococcus lactis subsp. cremoris KW2	56.604	98.148	0.556
comYC	Streptococcus suis isolate S10	60.227	81.481	0.491
comGC	Staphylococcus aureus MW2	50	72.222	0.361
comGC	Staphylococcus aureus N315	50	72.222	0.361