Detailed information NTG1145111

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: STACADC2_RS08450
• Genome accession: NZ_LT604076
• Coordinates: 1593247..1593684 (-)
• Length: 145 a.a.
• NCBI ID: WP_022096897.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain ACA-DC
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1588247..1598684

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STACADC2_RS08415 (STACADC2_1628)	-	1588301..1588963 (-)	663	WP_087010194.1	CPBP family intramembrane glutamic endopeptidase	-
STACADC2_RS08420 (STACADC2_1629)	-	1589066..1589509 (-)	444	WP_087010195.1	CAAX protease	-
STACADC2_RS10180 (STACADC2_1630)	-	1589583..1590008 (-)	426	WP_087010196.1	CPBP family intramembrane glutamic endopeptidase	-
STACADC2_RS08430 (STACADC2_1631)	-	1590256..1590453 (-)	198	WP_002885716.1	helix-turn-helix transcriptional regulator	-
STACADC2_RS08435 (STACADC2_1632)	-	1590702..1591895 (-)	1194	WP_087010197.1	acetate kinase	-
STACADC2_RS08440 (STACADC2_1633)	comYH	1591951..1592907 (-)	957	WP_011226622.1	class I SAM-dependent methyltransferase	Machinery gene
STACADC2_RS08445 (STACADC2_1634)	comGG	1592952..1593269 (-)	318	WP_002952035.1	competence type IV pilus minor pilin ComGG	-
STACADC2_RS08450 (STACADC2_1635)	comYF	1593247..1593684 (-)	438	WP_022096897.1	competence type IV pilus minor pilin ComGF	Machinery gene
STACADC2_RS08455 (STACADC2_1636)	comGE	1593668..1593961 (-)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	-
STACADC2_RS08460 (STACADC2_1637)	comYD	1593933..1594361 (-)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
STACADC2_RS08465 (STACADC2_1638)	comYC	1594321..1594647 (-)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
STACADC2_RS08470 (STACADC2_1639)	comYB	1594644..1595744 (-)	1101	WP_157659050.1	competence type IV pilus assembly protein ComGB	Machinery gene
STACADC2_RS08475 (STACADC2_1640)	comGA/cglA/cilD	1595626..1596567 (-)	942	WP_022096896.1	competence type IV pilus ATPase ComGA	Machinery gene
STACADC2_RS08480 (STACADC2_1641)	-	1596648..1597010 (-)	363	WP_087010198.1	DUF1033 family protein	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16375.89 Da
• Isoelectric Point: 8.9784

>NTDB_id=1145111 STACADC2_RS08450 WP_022096897.1 1593247..1593684(-) (comYF) [Streptococcus thermophilus strain ACA-DC]
MYLSSKLRAFTLLECLVALLVIAGSVQVYQGLTTVLVSNVKQVRQQENQDWLLFVQQMEAELEGCQLVKVEGNKLYVKKD
NQDLAFGLSSASDFRKTNADGRGYQPMLFDVKSSKVSQKNQIVTIQVTLKNELQRSFVYAFEKTG

Nucleotide

• Length: 438 bp

>NTDB_id=1145111 STACADC2_RS08450 WP_022096897.1 1593247..1593684(-) (comYF) [Streptococcus thermophilus strain ACA-DC]
ATGTATCTAAGCAGTAAGCTGCGTGCCTTTACCCTCTTGGAATGTCTAGTGGCCTTGTTGGTCATTGCTGGCTCAGTTCA
AGTTTATCAAGGGTTAACCACTGTACTTGTGAGTAATGTTAAGCAGGTAAGACAACAAGAAAACCAAGATTGGCTTCTAT
TTGTTCAACAAATGGAGGCAGAATTAGAAGGATGTCAGTTGGTCAAGGTAGAGGGGAACAAACTCTATGTCAAGAAGGAT
AATCAAGACTTGGCTTTTGGTCTTTCAAGTGCCTCTGATTTTCGAAAAACAAATGCTGATGGTCGAGGTTATCAACCAAT
GCTTTTCGATGTCAAATCTAGTAAGGTAAGTCAAAAGAACCAGATAGTTACCATCCAAGTGACTCTTAAAAATGAACTAC
AAAGGAGTTTTGTTTATGCTTTTGAAAAAACAGGTTAG

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (39-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	58.865	97.241	0.572
comYF	Streptococcus mutans UA159	58.156	97.241	0.566
comGF/cglF	Streptococcus pneumoniae D39	48.571	96.552	0.469
comGF/cglF	Streptococcus pneumoniae Rx1	48.571	96.552	0.469
comGF/cglF	Streptococcus pneumoniae R6	48.571	96.552	0.469
comGF/cglF	Streptococcus pneumoniae TIGR4	48.571	96.552	0.469
comGF/cglF	Streptococcus mitis NCTC 12261	46.809	97.241	0.455
comGF/cglF	Streptococcus mitis SK321	46.099	97.241	0.448
comGF	Lactococcus lactis subsp. cremoris KW2	46.043	95.862	0.441