Detailed information NTG1142942

Bioinformatically predicted

Overview

• Name: comGC/cglC
• Type: Machinery gene
• Locus tag: DQL00_RS03755
• Genome accession: NZ_LS483523
• Coordinates: 710472..710798 (+)
• Length: 108 a.a.
• NCBI ID: WP_000738627.1
• Uniprot ID: A0A0H2URU9
• Organism: Streptococcus pneumoniae strain 4041STDY6836169
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 705472..715798

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL00_RS03730	-	705495..706553 (+)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-
DQL00_RS03740	-	708124..708489 (+)	366	WP_023396479.1	DUF1033 family protein	-
DQL00_RS03745	comGA/cglA/cilD	708565..709506 (+)	942	WP_000249564.1	competence type IV pilus ATPase ComGA	Machinery gene
DQL00_RS03750	comGB/cglB	709454..710470 (+)	1017	WP_074196785.1	competence type IV pilus assembly protein ComGB	Machinery gene
DQL00_RS03755	comGC/cglC	710472..710798 (+)	327	WP_000738627.1	comG operon protein ComGC	Machinery gene
DQL00_RS03760	comGD/cglD	710791..711195 (+)	405	WP_000588028.1	competence type IV pilus minor pilin ComGD	Machinery gene
DQL00_RS03765	comGE/cglE	711158..711460 (+)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
DQL00_RS03770	comGF/cglF	711423..711884 (+)	462	WP_000250534.1	competence type IV pilus minor pilin ComGF	Machinery gene
DQL00_RS03775	comGG/cglG	711862..712275 (+)	414	WP_000265622.1	competence type IV pilus minor pilin ComGG	Machinery gene
DQL00_RS03780	-	712412..713006 (+)	595	Protein_695	class I SAM-dependent methyltransferase	-
DQL00_RS03785	comYH	713067..714020 (+)	954	WP_000345135.1	class I SAM-dependent methyltransferase	Machinery gene
DQL00_RS03790	-	714071..715261 (+)	1191	WP_000167757.1	acetate kinase	-
DQL00_RS12225	-	715262..715393 (+)	132	WP_000768904.1	hypothetical protein	-
DQL00_RS03795	rnpA	715410..715781 (+)	372	WP_000739253.1	ribonuclease P protein component	-

Sequence

Protein

• Length: 108 a.a.
• Molecular weight: 12177.34 Da
• Isoelectric Point: 10.1876

>NTDB_id=1142942 DQL00_RS03755 WP_000738627.1 710472..710798(+) (comGC/cglC) [Streptococcus pneumoniae strain 4041STDY6836169]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDASLRKLQA
DGRITEEQAKAYKEYNDKNGGANRKVND

Nucleotide

• Length: 327 bp

>NTDB_id=1142942 DQL00_RS03755 WP_000738627.1 710472..710798(+) (comGC/cglC) [Streptococcus pneumoniae strain 4041STDY6836169]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGGTGGAGATGTTGGTGGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTAGAAAAGAATGAAGATGCTAGCCTAAGAAAGTTACAAGCA
GATGGACGCATCACGGAAGAACAGGCTAAAGCTTATAAAGAATACAATGATAAAAATGGAGGAGCAAATCGTAAAGTCAA
TGATTAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (11-34)

3D structure

• PDB: 5NCA

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGC/cglC	Streptococcus pneumoniae TIGR4	100	100	1
comGC/cglC	Streptococcus pneumoniae Rx1	99.074	100	0.991
comGC/cglC	Streptococcus pneumoniae D39	99.074	100	0.991
comGC/cglC	Streptococcus pneumoniae R6	99.074	100	0.991
comGC/cglC	Streptococcus mitis SK321	94.444	100	0.944
comGC/cglC	Streptococcus mitis NCTC 12261	94.898	90.741	0.861
comYC	Streptococcus gordonii str. Challis substr. CH1	67.961	95.37	0.648
comYC	Streptococcus mutans UA140	62.745	94.444	0.593
comYC	Streptococcus mutans UA159	62.745	94.444	0.593
comYC	Streptococcus suis isolate S10	70.37	75	0.528
comGC	Lactococcus lactis subsp. cremoris KW2	53.922	94.444	0.509
comGC	Staphylococcus aureus MW2	50	79.63	0.398
comGC	Staphylococcus aureus N315	50	79.63	0.398
comGC	Latilactobacillus sakei subsp. sakei 23K	45.349	79.63	0.361