Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGF/cglF   Type   Machinery gene
Locus tag   DQL00_RS03770 Genome accession   NZ_LS483523
Coordinates   711423..711884 (+) Length   153 a.a.
NCBI ID   WP_000250534.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 4041STDY6836169     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 706423..716884
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL00_RS03740 - 708124..708489 (+) 366 WP_023396479.1 DUF1033 family protein -
  DQL00_RS03745 comGA/cglA/cilD 708565..709506 (+) 942 WP_000249564.1 competence type IV pilus ATPase ComGA Machinery gene
  DQL00_RS03750 comGB/cglB 709454..710470 (+) 1017 WP_074196785.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQL00_RS03755 comGC/cglC 710472..710798 (+) 327 WP_000738627.1 comG operon protein ComGC Machinery gene
  DQL00_RS03760 comGD/cglD 710791..711195 (+) 405 WP_000588028.1 competence type IV pilus minor pilin ComGD Machinery gene
  DQL00_RS03765 comGE/cglE 711158..711460 (+) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  DQL00_RS03770 comGF/cglF 711423..711884 (+) 462 WP_000250534.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQL00_RS03775 comGG/cglG 711862..712275 (+) 414 WP_000265622.1 competence type IV pilus minor pilin ComGG Machinery gene
  DQL00_RS03780 - 712412..713006 (+) 595 Protein_695 class I SAM-dependent methyltransferase -
  DQL00_RS03785 comYH 713067..714020 (+) 954 WP_000345135.1 class I SAM-dependent methyltransferase Machinery gene
  DQL00_RS03790 - 714071..715261 (+) 1191 WP_000167757.1 acetate kinase -
  DQL00_RS12225 - 715262..715393 (+) 132 WP_000768904.1 hypothetical protein -
  DQL00_RS03795 rnpA 715410..715781 (+) 372 WP_000739253.1 ribonuclease P protein component -
  DQL00_RS03800 - 715756..716580 (+) 825 WP_000727904.1 membrane protein insertase YidC -

Sequence

Protein


Download         Length: 153 a.a.        Molecular weight: 17972.67 Da        Isoelectric Point: 9.6092

>NTDB_id=1142945 DQL00_RS03770 WP_000250534.1 711423..711884(+) (comGF/cglF) [Streptococcus pneumoniae strain 4041STDY6836169]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLISEVRYQQQSEQKEWLLFVDQLEVELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTNARGRGYQPMVYGLKSVRITEDNQLVRFHFQFQKGLEREFIYRVEKEKS

Nucleotide


Download         Length: 462 bp        

>NTDB_id=1142945 DQL00_RS03770 WP_000250534.1 711423..711884(+) (comGF/cglF) [Streptococcus pneumoniae strain 4041STDY6836169]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTGCTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAGCTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAACTTGAGGTAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGATGATTTCCGTAAAACGAATGCTCG
TGGTCGAGGTTATCAGCCTATGGTTTATGGACTCAAATCTGTACGGATTACAGAGGACAATCAACTGGTTCGCTTTCATT
TCCAGTTCCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAAAAAGTTAA

Domains

Predicted by InterproScan.

Putative Competence protein ComGF (ComGF)

(45-141)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGF/cglF Streptococcus pneumoniae Rx1

100

100

1
  comGF/cglF Streptococcus pneumoniae D39

100

100

1
  comGF/cglF Streptococcus pneumoniae R6

100

100

1
  comGF/cglF Streptococcus pneumoniae TIGR4

100

100

1
  comGF/cglF Streptococcus mitis SK321

90.85

100

0.909
  comGF/cglF Streptococcus mitis NCTC 12261

89.542

100

0.895

Multiple sequence alignment