Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   DQL00_RS03785 Genome accession   NZ_LS483523
Coordinates   713067..714020 (+) Length   317 a.a.
NCBI ID   WP_000345135.1    Uniprot ID   A0A2U3RW99
Organism   Streptococcus pneumoniae strain 4041STDY6836169     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 708067..719020
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL00_RS03740 - 708124..708489 (+) 366 WP_023396479.1 DUF1033 family protein -
  DQL00_RS03745 comGA/cglA/cilD 708565..709506 (+) 942 WP_000249564.1 competence type IV pilus ATPase ComGA Machinery gene
  DQL00_RS03750 comGB/cglB 709454..710470 (+) 1017 WP_074196785.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQL00_RS03755 comGC/cglC 710472..710798 (+) 327 WP_000738627.1 comG operon protein ComGC Machinery gene
  DQL00_RS03760 comGD/cglD 710791..711195 (+) 405 WP_000588028.1 competence type IV pilus minor pilin ComGD Machinery gene
  DQL00_RS03765 comGE/cglE 711158..711460 (+) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  DQL00_RS03770 comGF/cglF 711423..711884 (+) 462 WP_000250534.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQL00_RS03775 comGG/cglG 711862..712275 (+) 414 WP_000265622.1 competence type IV pilus minor pilin ComGG Machinery gene
  DQL00_RS03780 - 712412..713006 (+) 595 Protein_695 class I SAM-dependent methyltransferase -
  DQL00_RS03785 comYH 713067..714020 (+) 954 WP_000345135.1 class I SAM-dependent methyltransferase Machinery gene
  DQL00_RS03790 - 714071..715261 (+) 1191 WP_000167757.1 acetate kinase -
  DQL00_RS12225 - 715262..715393 (+) 132 WP_000768904.1 hypothetical protein -
  DQL00_RS03795 rnpA 715410..715781 (+) 372 WP_000739253.1 ribonuclease P protein component -
  DQL00_RS03800 - 715756..716580 (+) 825 WP_000727904.1 membrane protein insertase YidC -
  DQL00_RS03805 jag 716599..717585 (+) 987 WP_000260012.1 RNA-binding cell elongation regulator Jag/EloR -
  DQL00_RS03810 - 717636..718259 (+) 624 WP_000932644.1 hypothetical protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35756.99 Da        Isoelectric Point: 4.2748

>NTDB_id=1142947 DQL00_RS03785 WP_000345135.1 713067..714020(+) (comYH) [Streptococcus pneumoniae strain 4041STDY6836169]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELNQVKENNQTLKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFKEEEITILEMGSGMGILGAIFLTSLTKKVDYLGMEVDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGLKYLKSDGYAIFLAPSDLLTSPQ
SDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFILQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=1142947 DQL00_RS03785 WP_000345135.1 713067..714020(+) (comYH) [Streptococcus pneumoniae strain 4041STDY6836169]
ATGGATTTTGAAAAAATTGAACAAGCTTATACCTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAATAGCATCTATCTGGATGGTGAAACTGAGCTAAACCAGGTCAAGGAGAACAATC
AAACCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACACCGGATGCTATTGCTTTGCTTTTGGTGTTTATTGTGGAAGAGTTGTTTAA
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTCTAGGCGCTATTTTCTTGACCTCGCTTACTAAAA
AGGTGGATTACTTGGGAATGGAAGTGGATGATTTGCTGATTGATCTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGCCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTCGG
CTATTATCCTGATGATGCCGTTGCGTCGCGCCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCCCATCACTTGCTCA
TGGAACAAGGGCTTAAGTACCTCAAGTCAGACGGATACGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGTCCTCAA
AGTGATTTGTTAAAAGAATGGCTGAAAGAAGAGGCGAGTCTGGTTGCTATGATTAGTCTGCCTGAAAATCTCTTTGCTAA
TGCCAAACAATCTAAGACTATTTTTATCTTACAGAAGAAAAATGAAATAGCAGTAGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2U3RW99

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

54.633

98.738

0.539
  comYH Streptococcus mutans UA159

54.313

98.738

0.536

Multiple sequence alignment