Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   DQM63_RS10560 Genome accession   NZ_LS483385
Coordinates   2116605..2117546 (-) Length   313 a.a.
NCBI ID   WP_002901721.1    Uniprot ID   -
Organism   Streptococcus sanguinis strain NCTC7863     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2111605..2122546
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM63_RS10525 (NCTC7863_02077) comYH 2112833..2113798 (-) 966 WP_002901707.1 class I SAM-dependent methyltransferase Machinery gene
  DQM63_RS10530 (NCTC7863_02078) comGG 2113880..2114269 (-) 390 WP_002901710.1 competence type IV pilus minor pilin ComGG -
  DQM63_RS10535 (NCTC7863_02079) comGF/cglF 2114250..2114687 (-) 438 WP_002901713.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQM63_RS10540 (NCTC7863_02080) comGE/cglE 2114671..2114964 (-) 294 WP_002914478.1 competence type IV pilus minor pilin ComGE Machinery gene
  DQM63_RS10545 (NCTC7863_02081) comYD 2114930..2115364 (-) 435 WP_002901717.1 competence type IV pilus minor pilin ComGD Machinery gene
  DQM63_RS10550 (NCTC7863_02082) comYC 2115324..2115641 (-) 318 WP_002896769.1 competence type IV pilus major pilin ComGC Machinery gene
  DQM63_RS10555 (NCTC7863_02083) comYB 2115641..2116675 (-) 1035 WP_263281106.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQM63_RS10560 (NCTC7863_02084) comYA 2116605..2117546 (-) 942 WP_002901721.1 competence type IV pilus ATPase ComGA Machinery gene
  DQM63_RS10565 (NCTC7863_02085) - 2117676..2118056 (-) 381 WP_002901723.1 DUF1033 family protein -
  DQM63_RS10575 (NCTC7863_02086) - 2118375..2119481 (-) 1107 WP_002901727.1 glycosyl hydrolase family 8 -
  DQM63_RS10580 (NCTC7863_02087) - 2119490..2120800 (-) 1311 WP_002901729.1 glycosyltransferase -
  DQM63_RS10585 (NCTC7863_02088) - 2120793..2120936 (-) 144 WP_002896778.1 hypothetical protein -
  DQM63_RS10590 (NCTC7863_02089) - 2120948..2121736 (-) 789 WP_002901732.1 hypothetical protein -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35940.23 Da        Isoelectric Point: 6.3970

>NTDB_id=1139658 DQM63_RS10560 WP_002901721.1 2116605..2117546(-) (comYA) [Streptococcus sanguinis strain NCTC7863]
MVQEIAKEMIRQARQEGAQDIYLIPKTTCYELYMRIGDERRFIKTYDFEILSAVISHFKFVAGMNVGEKRRSQLGSCDYD
CEEAKVSIRLSSVGDYRGFESLVIRLLHDEDRELRFWFEQLPELRKKIQARGLYLFSGPVGSGKTTLMYHLAQLKFSGQQ
VMSIEDPVEIKQEAMLQLQLNETIGMTYDSLIKLSLRHRPDLLIIGEIRDRETARAVVRASLTGATVFSTIHAKSVRGVY
ERLLELGVSEDELRMVLQGVCYQRLIGGGGVVDFVSQNYQEHKAEVWNQQIDQLFAEGHISAEQRQTEKIVYA

Nucleotide


Download         Length: 942 bp        

>NTDB_id=1139658 DQM63_RS10560 WP_002901721.1 2116605..2117546(-) (comYA) [Streptococcus sanguinis strain NCTC7863]
ATGGTTCAAGAAATTGCAAAAGAAATGATTAGGCAGGCTCGGCAAGAGGGGGCGCAGGATATTTACCTCATTCCTAAGAC
TACTTGCTATGAGCTTTATATGAGAATCGGTGATGAACGTCGCTTTATAAAAACTTATGATTTTGAGATTCTGTCAGCTG
TTATCAGCCACTTTAAGTTTGTCGCAGGTATGAATGTTGGAGAGAAGCGCCGCAGTCAGCTTGGGTCATGCGATTATGAC
TGTGAGGAAGCAAAGGTTTCAATCCGGCTTTCGTCAGTTGGGGATTACCGTGGTTTTGAAAGTCTGGTTATCCGGCTCCT
GCATGATGAAGACAGGGAGCTGCGCTTTTGGTTTGAGCAATTGCCGGAGCTGCGCAAGAAAATTCAAGCTCGCGGTCTCT
ATCTTTTCTCGGGTCCAGTCGGCAGTGGCAAGACAACCTTAATGTACCATTTGGCTCAGCTCAAATTTTCTGGTCAGCAG
GTTATGTCGATTGAAGATCCGGTTGAGATTAAGCAAGAGGCTATGCTGCAGCTGCAGCTGAACGAAACCATTGGCATGAC
TTATGACAGTCTGATTAAGCTGTCTCTGCGACATCGGCCGGATCTCTTGATTATCGGGGAAATTCGTGATCGAGAGACAG
CTAGGGCAGTGGTTCGGGCAAGTTTGACCGGAGCTACGGTCTTTTCAACGATTCATGCCAAGAGTGTTCGCGGTGTCTAT
GAGCGGCTTTTGGAATTGGGCGTTAGCGAGGATGAGCTAAGAATGGTGCTTCAAGGTGTTTGTTACCAGCGTTTAATTGG
GGGAGGAGGTGTCGTTGATTTTGTCAGTCAAAACTATCAAGAGCACAAAGCCGAAGTCTGGAATCAGCAGATTGATCAGC
TTTTTGCAGAAGGACATATCAGTGCTGAGCAAAGGCAGACCGAAAAAATTGTCTACGCCTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

80

99.042

0.792
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

74.441

100

0.744
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

74.441

100

0.744
  comGA/cglA/cilD Streptococcus pneumoniae D39

74.441

100

0.744
  comGA/cglA/cilD Streptococcus pneumoniae R6

74.441

100

0.744
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

74.441

100

0.744
  comYA Streptococcus mutans UA159

66.238

99.361

0.658
  comYA Streptococcus mutans UA140

66.238

99.361

0.658
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

64.839

99.042

0.642
  comGA Lactococcus lactis subsp. cremoris KW2

55.128

99.681

0.55
  comGA Latilactobacillus sakei subsp. sakei 23K

40.647

88.818

0.361

Multiple sequence alignment