Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   DQM63_RS10555 Genome accession   NZ_LS483385
Coordinates   2115641..2116675 (-) Length   344 a.a.
NCBI ID   WP_263281106.1    Uniprot ID   -
Organism   Streptococcus sanguinis strain NCTC7863     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2110641..2121675
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM63_RS10515 (NCTC7863_02075) - 2110719..2111468 (-) 750 WP_032909647.1 CPBP family intramembrane glutamic endopeptidase -
  DQM63_RS10520 (NCTC7863_02076) - 2111603..2112796 (-) 1194 WP_002901705.1 acetate kinase -
  DQM63_RS10525 (NCTC7863_02077) comYH 2112833..2113798 (-) 966 WP_002901707.1 class I SAM-dependent methyltransferase Machinery gene
  DQM63_RS10530 (NCTC7863_02078) comGG 2113880..2114269 (-) 390 WP_002901710.1 competence type IV pilus minor pilin ComGG -
  DQM63_RS10535 (NCTC7863_02079) comGF/cglF 2114250..2114687 (-) 438 WP_002901713.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQM63_RS10540 (NCTC7863_02080) comGE/cglE 2114671..2114964 (-) 294 WP_002914478.1 competence type IV pilus minor pilin ComGE Machinery gene
  DQM63_RS10545 (NCTC7863_02081) comYD 2114930..2115364 (-) 435 WP_002901717.1 competence type IV pilus minor pilin ComGD Machinery gene
  DQM63_RS10550 (NCTC7863_02082) comYC 2115324..2115641 (-) 318 WP_002896769.1 competence type IV pilus major pilin ComGC Machinery gene
  DQM63_RS10555 (NCTC7863_02083) comYB 2115641..2116675 (-) 1035 WP_263281106.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQM63_RS10560 (NCTC7863_02084) comYA 2116605..2117546 (-) 942 WP_002901721.1 competence type IV pilus ATPase ComGA Machinery gene
  DQM63_RS10565 (NCTC7863_02085) - 2117676..2118056 (-) 381 WP_002901723.1 DUF1033 family protein -
  DQM63_RS10575 (NCTC7863_02086) - 2118375..2119481 (-) 1107 WP_002901727.1 glycosyl hydrolase family 8 -
  DQM63_RS10580 (NCTC7863_02087) - 2119490..2120800 (-) 1311 WP_002901729.1 glycosyltransferase -
  DQM63_RS10585 (NCTC7863_02088) - 2120793..2120936 (-) 144 WP_002896778.1 hypothetical protein -

Sequence

Protein


Download         Length: 344 a.a.        Molecular weight: 39039.02 Da        Isoelectric Point: 9.1627

>NTDB_id=1139657 DQM63_RS10555 WP_263281106.1 2115641..2116675(-) (comYB) [Streptococcus sanguinis strain NCTC7863]
MISFLQKDISVLSKGRPKKLSTPKQKKIIELFHNLFSSGFHLAEIVDFLRRSALLEEVYVTEMRAGLSAGQSFSEIVSRL
GFSDSVVTQLSLSELHGNLTLSLGKIEAYLENLSKVKKKLIEVGTYPLMLLGFLVLIMLGLRNYLLPQLDSQNLATQLIN
HLPQIFFWSILALAVLVSVALFYYRKSSKIRFFSKLAALPFIGRLVQAYLTAYYAREWGNMIGQGLELSQIFAIMQEQPS
QLFQEIGEDMAAALQGGQGYADKVASYPFFKKELSLMIEYGEVKSKLGSELEVYAEKTWEEFFLRINRAMNFIQPLVFIF
VALVIVLLYAAMLLPIYQNMEVHL

Nucleotide


Download         Length: 1035 bp        

>NTDB_id=1139657 DQM63_RS10555 WP_263281106.1 2115641..2116675(-) (comYB) [Streptococcus sanguinis strain NCTC7863]
TTGATCAGCTTTTTGCAGAAGGACATATCAGTGCTGAGCAAAGGCAGACCGAAAAAATTGTCTACGCCTAAGCAGAAAAA
GATTATTGAGCTCTTTCATAATCTCTTCAGCAGCGGTTTTCACCTAGCAGAGATTGTAGACTTTCTGAGACGAAGTGCCT
TGTTGGAGGAAGTATATGTCACTGAAATGCGGGCAGGCTTGTCAGCTGGTCAGTCCTTTTCAGAGATTGTCAGTCGACTG
GGATTTTCCGACAGTGTTGTAACCCAGCTTTCCTTATCTGAGCTGCATGGCAATCTGACACTTAGTTTGGGCAAGATTGA
GGCCTATCTGGAAAATCTGTCCAAGGTTAAGAAAAAATTGATAGAGGTAGGGACCTATCCTCTCATGCTGCTGGGCTTTT
TGGTCCTTATCATGCTGGGATTGCGCAACTATCTTCTGCCTCAATTGGACAGCCAGAATCTAGCTACTCAGCTGATTAAT
CACCTGCCTCAGATCTTTTTTTGGAGCATCCTTGCTTTAGCTGTCTTGGTTTCAGTGGCTCTCTTTTACTATCGAAAGTC
ATCCAAGATTCGTTTTTTCAGCAAACTAGCAGCTCTGCCATTTATTGGACGTTTGGTACAGGCTTACTTGACCGCTTATT
ATGCTCGTGAATGGGGAAATATGATTGGTCAGGGCTTGGAACTGAGTCAGATTTTTGCGATTATGCAGGAGCAGCCTTCC
CAGCTCTTTCAGGAAATCGGAGAAGATATGGCTGCTGCTTTGCAAGGCGGTCAAGGCTATGCGGACAAGGTGGCAAGCTA
TCCTTTCTTTAAGAAAGAATTGTCCTTGATGATCGAGTATGGTGAGGTCAAGTCCAAGCTGGGGAGTGAACTGGAAGTCT
ATGCTGAAAAGACATGGGAGGAATTTTTCCTACGTATCAACCGAGCCATGAATTTCATTCAGCCCCTAGTATTTATTTTT
GTTGCCTTAGTGATTGTTTTACTTTATGCGGCAATGCTCTTGCCCATTTATCAGAATATGGAGGTTCATTTGTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(215-335)

Type II secretion system (T2SS), protein F (T2SSF)

(29-147)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

73.837

100

0.738
  comGB/cglB Streptococcus mitis NCTC 12261

70.536

97.674

0.689
  comGB/cglB Streptococcus mitis SK321

69.048

97.674

0.674
  comGB/cglB Streptococcus pneumoniae TIGR4

68.75

97.674

0.672
  comGB/cglB Streptococcus pneumoniae R6

68.75

97.674

0.672
  comGB/cglB Streptococcus pneumoniae Rx1

68.75

97.674

0.672
  comGB/cglB Streptococcus pneumoniae D39

68.75

97.674

0.672
  comYB Streptococcus mutans UA140

60.641

99.709

0.605
  comYB Streptococcus mutans UA159

60.641

99.709

0.605
  comGB Lactococcus lactis subsp. cremoris KW2

52.071

98.256

0.512

Multiple sequence alignment