Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   DQM63_RS10540 Genome accession   NZ_LS483385
Coordinates   2114671..2114964 (-) Length   97 a.a.
NCBI ID   WP_002914478.1    Uniprot ID   -
Organism   Streptococcus sanguinis strain NCTC7863     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2109671..2119964
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM63_RS10510 (NCTC7863_02074) - 2109963..2110601 (-) 639 WP_002901701.1 hypothetical protein -
  DQM63_RS10515 (NCTC7863_02075) - 2110719..2111468 (-) 750 WP_032909647.1 CPBP family intramembrane glutamic endopeptidase -
  DQM63_RS10520 (NCTC7863_02076) - 2111603..2112796 (-) 1194 WP_002901705.1 acetate kinase -
  DQM63_RS10525 (NCTC7863_02077) comYH 2112833..2113798 (-) 966 WP_002901707.1 class I SAM-dependent methyltransferase Machinery gene
  DQM63_RS10530 (NCTC7863_02078) comGG 2113880..2114269 (-) 390 WP_002901710.1 competence type IV pilus minor pilin ComGG -
  DQM63_RS10535 (NCTC7863_02079) comGF/cglF 2114250..2114687 (-) 438 WP_002901713.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQM63_RS10540 (NCTC7863_02080) comGE/cglE 2114671..2114964 (-) 294 WP_002914478.1 competence type IV pilus minor pilin ComGE Machinery gene
  DQM63_RS10545 (NCTC7863_02081) comYD 2114930..2115364 (-) 435 WP_002901717.1 competence type IV pilus minor pilin ComGD Machinery gene
  DQM63_RS10550 (NCTC7863_02082) comYC 2115324..2115641 (-) 318 WP_002896769.1 competence type IV pilus major pilin ComGC Machinery gene
  DQM63_RS10555 (NCTC7863_02083) comYB 2115641..2116675 (-) 1035 WP_263281106.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQM63_RS10560 (NCTC7863_02084) comYA 2116605..2117546 (-) 942 WP_002901721.1 competence type IV pilus ATPase ComGA Machinery gene
  DQM63_RS10565 (NCTC7863_02085) - 2117676..2118056 (-) 381 WP_002901723.1 DUF1033 family protein -
  DQM63_RS10575 (NCTC7863_02086) - 2118375..2119481 (-) 1107 WP_002901727.1 glycosyl hydrolase family 8 -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10892.86 Da        Isoelectric Point: 9.9250

>NTDB_id=1139654 DQM63_RS10540 WP_002914478.1 2114671..2114964(-) (comGE/cglE) [Streptococcus sanguinis strain NCTC7863]
MASLKRQRLQASILLEALVAMAIFAAIASLLLGQISQSRKEQQILLQQEEVLRVARMALQTGQEELHINGIAVRQLKTDK
QLLVYHEGEVVIHVQKP

Nucleotide


Download         Length: 294 bp        

>NTDB_id=1139654 DQM63_RS10540 WP_002914478.1 2114671..2114964(-) (comGE/cglE) [Streptococcus sanguinis strain NCTC7863]
ATGGCAAGTTTAAAAAGACAACGGCTTCAAGCTAGCATTCTGCTGGAAGCTCTGGTTGCCATGGCAATTTTTGCGGCTAT
TGCCAGTCTGCTTCTGGGACAGATTAGCCAGTCTCGTAAAGAGCAGCAGATCCTTCTGCAGCAGGAAGAGGTGCTTCGGG
TAGCTCGTATGGCCCTGCAAACAGGACAAGAAGAGCTTCATATCAATGGAATTGCTGTGCGTCAGCTTAAGACAGATAAG
CAGCTACTGGTCTATCACGAAGGGGAGGTGGTTATCCATGTCCAAAAACCTTAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae TIGR4

51.546

100

0.515
  comGE/cglE Streptococcus pneumoniae Rx1

51.546

100

0.515
  comGE/cglE Streptococcus pneumoniae D39

51.546

100

0.515
  comGE/cglE Streptococcus pneumoniae R6

51.546

100

0.515
  comGE/cglE Streptococcus mitis NCTC 12261

50.515

100

0.505
  comGE/cglE Streptococcus mitis SK321

50.515

100

0.505
  comYE Streptococcus mutans UA140

42.268

100

0.423
  comYE Streptococcus mutans UA159

42.268

100

0.423

Multiple sequence alignment