Detailed information NTG1138923

Bioinformatically predicted

Overview

• Name: comX/sigX/comX2/sigX2
• Type: Regulator
• Locus tag: DQM56_RS08850
• Genome accession: NZ_LS483368
• Coordinates: 1830529..1831014 (-)
• Length: 161 a.a.
• NCBI ID: WP_014623459.1
• Uniprot ID: A0A6D2L510
• Organism: Streptococcus equi subsp. zooepidemicus strain NCTC6176
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1825529..1836014

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM56_RS08825 (NCTC6176_01789)	-	1825993..1826553 (-)	561	WP_111710822.1	TIGR01440 family protein	-
DQM56_RS08830 (NCTC6176_01790)	-	1826566..1827039 (-)	474	WP_042671321.1	ECF transporter S component	-
DQM56_RS08835 (NCTC6176_01791)	-	1827045..1827794 (-)	750	WP_111710823.1	bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase	-
DQM56_RS08840 (NCTC6176_01792)	truA	1827784..1828533 (-)	750	WP_111710824.1	tRNA pseudouridine(38-40) synthase TruA	-
DQM56_RS08845 (NCTC6176_01793)	-	1828720..1830084 (+)	1365	WP_111710825.1	aspartate kinase	-
DQM56_RS08850 (NCTC6176_01794)	comX/sigX/comX2/sigX2	1830529..1831014 (-)	486	WP_014623459.1	hypothetical protein	Regulator

Sequence

Protein

• Length: 161 a.a.
• Molecular weight: 19403.39 Da
• Isoelectric Point: 8.2702

>NTDB_id=1138923 DQM56_RS08850 WP_014623459.1 1830529..1831014(-) (comX/sigX/comX2/sigX2) [Streptococcus equi subsp. zooepidemicus strain NCTC6176]
MTDDLVRLFDKIKPIIMKLRRHYYIQLWELDDWLQEGRLILYRLLVTYPELIEDEEKLYRYFKTKFSSYLKDVLRQQESQ
KRRFHKMAYEEIGSVGHAIPAGGLGVDDYVAYQLIVKEVEERLTESELSQFRALIRGERFEGRRALLRKIGPYFQDFTGE
K

Nucleotide

• Length: 486 bp

>NTDB_id=1138923 DQM56_RS08850 WP_014623459.1 1830529..1831014(-) (comX/sigX/comX2/sigX2) [Streptococcus equi subsp. zooepidemicus strain NCTC6176]
ATGACTGATGATTTAGTGAGGTTGTTTGATAAGATCAAGCCTATTATTATGAAGCTAAGACGGCATTATTATATTCAGCT
GTGGGAGCTAGATGATTGGTTACAGGAGGGGCGGTTGATCTTGTATCGGTTATTGGTCACTTATCCAGAATTGATAGAGG
ATGAGGAGAAGCTGTATCGTTATTTTAAGACCAAGTTTTCTTCTTATTTGAAGGACGTGTTGCGGCAGCAGGAGAGTCAG
AAGCGTCGGTTTCATAAGATGGCTTATGAGGAGATTGGGTCGGTAGGCCATGCGATACCAGCAGGTGGCTTGGGAGTAGA
TGATTATGTGGCTTATCAGTTGATTGTGAAGGAGGTTGAGGAGCGATTGACAGAGAGTGAGCTGTCGCAGTTTCGGGCTT
TGATCAGGGGAGAGCGGTTTGAGGGGAGACGGGCCTTGCTTCGCAAGATAGGACCTTACTTTCAGGACTTTACTGGTGAG
AAATAA

Domains

No domain identified.

3D structure

• AlphaFold DB: A0A6D2L510

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	67.5	99.379	0.671
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	67.5	99.379	0.671
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	67.5	99.379	0.671
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	67.5	99.379	0.671
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	70.395	94.41	0.665
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	70.395	94.41	0.665
comX/sigX	Streptococcus infantarius subsp. infantarius ATCC BAA-102	47.742	96.273	0.46
comX/sigX	Streptococcus mutans UA159	46.497	97.516	0.453
comX	Streptococcus sobrinus strain NIDR 6715-7	45.752	95.031	0.435
comX/sigX/comX2/sigX2	Streptococcus mitis SK321	40.667	93.168	0.379
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	40.397	93.789	0.379
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	40.397	93.789	0.379
comX/sigX/comX1/sigX1	Streptococcus mitis SK321	39.333	93.168	0.366
comX/comX2	Streptococcus pneumoniae TIGR4	38.411	93.789	0.36
comX/comX1	Streptococcus pneumoniae TIGR4	38.411	93.789	0.36
comX/comX2	Streptococcus pneumoniae Rx1	38.411	93.789	0.36
comX/comX1	Streptococcus pneumoniae Rx1	38.411	93.789	0.36
comX/comX2	Streptococcus pneumoniae D39	38.411	93.789	0.36
comX/comX1	Streptococcus pneumoniae D39	38.411	93.789	0.36
comX/comX2	Streptococcus pneumoniae R6	38.411	93.789	0.36
comX/comX1	Streptococcus pneumoniae R6	38.411	93.789	0.36
comX/sigX/comX2/sigX2	Streptococcus mitis NCTC 12261	38.667	93.168	0.36
comX	Streptococcus thermophilus LMG 18311	37.908	95.031	0.36
comX	Streptococcus thermophilus LMD-9	37.908	95.031	0.36