Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX/comX2/sigX2   Type   Regulator
Locus tag   DQM56_RS08560 Genome accession   NZ_LS483368
Coordinates   1774708..1775193 (-) Length   161 a.a.
NCBI ID   WP_014623459.1    Uniprot ID   A0A6D2L510
Organism   Streptococcus equi subsp. zooepidemicus strain NCTC6176     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1769708..1780193
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM56_RS08525 (NCTC6176_01729) - 1770056..1770799 (-) 744 WP_012680083.1 class I SAM-dependent DNA methyltransferase -
  DQM56_RS08530 (NCTC6176_01730) rsfS 1770929..1771282 (-) 354 WP_111710807.1 ribosome silencing factor -
  DQM56_RS08535 (NCTC6176_01731) yqeK 1771284..1771877 (-) 594 WP_012677396.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  DQM56_RS08540 (NCTC6176_01732) - 1771874..1772506 (-) 633 WP_043026538.1 nicotinate-nucleotide adenylyltransferase -
  DQM56_RS08545 (NCTC6176_01733) yhbY 1772590..1772898 (-) 309 WP_012516273.1 ribosome assembly RNA-binding protein YhbY -
  DQM56_RS08550 (NCTC6176_01734) yqeH 1772925..1774043 (-) 1119 WP_111710808.1 ribosome biogenesis GTPase YqeH -
  DQM56_RS08555 (NCTC6176_01735) - 1774043..1774570 (-) 528 WP_111710809.1 YqeG family HAD IIIA-type phosphatase -
  DQM56_RS08560 (NCTC6176_01736) comX/sigX/comX2/sigX2 1774708..1775193 (-) 486 WP_014623459.1 hypothetical protein Regulator

Sequence

Protein


Download         Length: 161 a.a.        Molecular weight: 19403.39 Da        Isoelectric Point: 8.2702

>NTDB_id=1138916 DQM56_RS08560 WP_014623459.1 1774708..1775193(-) (comX/sigX/comX2/sigX2) [Streptococcus equi subsp. zooepidemicus strain NCTC6176]
MTDDLVRLFDKIKPIIMKLRRHYYIQLWELDDWLQEGRLILYRLLVTYPELIEDEEKLYRYFKTKFSSYLKDVLRQQESQ
KRRFHKMAYEEIGSVGHAIPAGGLGVDDYVAYQLIVKEVEERLTESELSQFRALIRGERFEGRRALLRKIGPYFQDFTGE
K

Nucleotide


Download         Length: 486 bp        

>NTDB_id=1138916 DQM56_RS08560 WP_014623459.1 1774708..1775193(-) (comX/sigX/comX2/sigX2) [Streptococcus equi subsp. zooepidemicus strain NCTC6176]
ATGACTGATGATTTAGTGAGGTTGTTTGATAAGATCAAGCCTATTATTATGAAGCTAAGACGGCATTATTATATTCAGCT
GTGGGAGCTAGATGATTGGTTACAGGAGGGGCGGTTGATCTTGTATCGGTTATTGGTCACTTATCCAGAATTGATAGAGG
ATGAGGAGAAGCTGTATCGTTATTTTAAGACCAAGTTTTCTTCTTATTTGAAGGACGTGTTGCGGCAGCAGGAGAGTCAG
AAGCGTCGGTTTCATAAGATGGCTTATGAGGAGATTGGGTCGGTAGGCCATGCGATACCAGCAGGTGGCTTGGGAGTAGA
TGATTATGTGGCTTATCAGTTGATTGTGAAGGAGGTTGAGGAGCGATTGACAGAGAGTGAGCTGTCGCAGTTTCGGGCTT
TGATCAGGGGAGAGCGGTTTGAGGGGAGACGGGCCTTGCTTCGCAAGATAGGACCTTACTTTCAGGACTTTACTGGTGAG
AAATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6D2L510

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

67.5

99.379

0.671
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

67.5

99.379

0.671
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

67.5

99.379

0.671
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

67.5

99.379

0.671
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

70.395

94.41

0.665
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

70.395

94.41

0.665
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

47.742

96.273

0.46
  comX/sigX Streptococcus mutans UA159

46.497

97.516

0.453
  comX Streptococcus sobrinus strain NIDR 6715-7

45.752

95.031

0.435
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

40.667

93.168

0.379
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

40.397

93.789

0.379
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

40.397

93.789

0.379
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

39.333

93.168

0.366
  comX/comX2 Streptococcus pneumoniae TIGR4

38.411

93.789

0.36
  comX/comX1 Streptococcus pneumoniae TIGR4

38.411

93.789

0.36
  comX/comX2 Streptococcus pneumoniae Rx1

38.411

93.789

0.36
  comX/comX1 Streptococcus pneumoniae Rx1

38.411

93.789

0.36
  comX/comX2 Streptococcus pneumoniae D39

38.411

93.789

0.36
  comX/comX1 Streptococcus pneumoniae D39

38.411

93.789

0.36
  comX/comX2 Streptococcus pneumoniae R6

38.411

93.789

0.36
  comX/comX1 Streptococcus pneumoniae R6

38.411

93.789

0.36
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

38.667

93.168

0.36
  comX Streptococcus thermophilus LMG 18311

37.908

95.031

0.36
  comX Streptococcus thermophilus LMD-9

37.908

95.031

0.36

Multiple sequence alignment