Detailed information    

insolico Bioinformatically predicted

Overview


Name   comYC   Type   Machinery gene
Locus tag   DQL21_RS01600 Genome accession   NZ_LS483343
Coordinates   295453..295767 (+) Length   104 a.a.
NCBI ID   WP_018031094.1    Uniprot ID   -
Organism   Streptococcus ferus strain NCTC12278     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 290453..300767
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL21_RS01575 (NCTC12278_00301) - 290748..291344 (+) 597 WP_018031089.1 PepSY domain-containing protein -
  DQL21_RS01580 (NCTC12278_00302) - 291488..292180 (+) 693 WP_018031090.1 response regulator transcription factor -
  DQL21_RS01585 (NCTC12278_00303) - 292143..293492 (+) 1350 WP_018031091.1 cell wall metabolism sensor histidine kinase WalK -
  DQL21_RS01590 (NCTC12278_00304) comYA 293545..294486 (+) 942 WP_018031092.1 competence type IV pilus ATPase ComGA Machinery gene
  DQL21_RS01595 (NCTC12278_00305) comYB 294383..295456 (+) 1074 WP_269458426.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQL21_RS01600 (NCTC12278_00306) comYC 295453..295767 (+) 315 WP_018031094.1 competence type IV pilus major pilin ComGC Machinery gene
  DQL21_RS01605 (NCTC12278_00307) comYD 295754..296167 (+) 414 WP_018031095.1 competence type IV pilus minor pilin ComGD Machinery gene
  DQL21_RS01610 (NCTC12278_00308) comGE 296157..296432 (+) 276 WP_018031096.1 competence type IV pilus minor pilin ComGE -
  DQL21_RS01615 (NCTC12278_00309) comYF 296398..296853 (+) 456 WP_040804182.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQL21_RS01620 (NCTC12278_00310) comGG 296831..297226 (+) 396 WP_018031098.1 competence type IV pilus minor pilin ComGG -
  DQL21_RS01625 (NCTC12278_00311) comYH 297276..298232 (+) 957 WP_018031099.1 class I SAM-dependent methyltransferase Machinery gene
  DQL21_RS01630 (NCTC12278_00312) - 298290..299483 (+) 1194 WP_018031100.1 acetate kinase -
  DQL21_RS01635 (NCTC12278_00313) - 299619..299816 (+) 198 WP_018031101.1 helix-turn-helix transcriptional regulator -
  DQL21_RS01640 (NCTC12278_00314) - 299877..300326 (+) 450 WP_018031102.1 hypothetical protein -

Sequence


Protein


Download         Length: 104 a.a.        Molecular weight: 11506.41 Da        Isoelectric Point: 9.3500

>NTDB_id=1137573 DQL21_RS01600 WP_018031094.1 295453..295767(+) (comYC) [Streptococcus ferus strain NCTC12278]
MKLLKTARLKAFTLIEMLVVLLIISVLLLLFVPNLTQQKDKVKDTGAAAVVKVVESQAELYELDNSGSASLSKLVASGDI
SKDQAESYRDYYAKHKDKQQHVAN

Nucleotide


Download         Length: 315 bp        

>NTDB_id=1137573 DQL21_RS01600 WP_018031094.1 295453..295767(+) (comYC) [Streptococcus ferus strain NCTC12278]
ATGAAATTACTCAAAACCGCTAGGTTAAAAGCATTCACCCTAATCGAAATGTTGGTTGTCTTATTAATTATCAGTGTTCT
ATTACTGCTTTTTGTGCCTAATTTAACCCAACAAAAGGATAAGGTCAAGGATACTGGGGCAGCTGCTGTCGTCAAGGTTG
TTGAGAGTCAGGCAGAGCTGTATGAACTGGACAACAGCGGATCGGCCAGCCTTTCTAAATTAGTAGCTTCTGGGGATATC
AGTAAGGACCAAGCGGAATCTTATCGTGACTATTACGCTAAACACAAGGATAAACAGCAACATGTGGCGAATTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYC Streptococcus mutans UA140

75.962

100

0.76

  comYC Streptococcus mutans UA159

75.962

100

0.76

  comYC Streptococcus gordonii str. Challis substr. CH1

70.476

100

0.712

  comGC/cglC Streptococcus mitis NCTC 12261

67.677

95.192

0.644

  comGC/cglC Streptococcus mitis SK321

70.526

91.346

0.644

  comGC/cglC Streptococcus pneumoniae TIGR4

61.765

98.077

0.606

  comGC/cglC Streptococcus pneumoniae D39

65.263

91.346

0.596

  comGC/cglC Streptococcus pneumoniae Rx1

65.263

91.346

0.596

  comGC/cglC Streptococcus pneumoniae R6

65.263

91.346

0.596

  comGC Lactococcus lactis subsp. cremoris KW2

56.842

91.346

0.519

  comYC Streptococcus suis isolate S10

60.227

84.615

0.51

  comGC Staphylococcus aureus MW2

48.235

81.731

0.394

  comGC Staphylococcus aureus N315

48.235

81.731

0.394


Multiple sequence alignment