Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   DQL21_RS01595 Genome accession   NZ_LS483343
Coordinates   294383..295456 (+) Length   357 a.a.
NCBI ID   WP_269458426.1    Uniprot ID   -
Organism   Streptococcus ferus strain NCTC12278     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 289383..300456
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL21_RS01570 (NCTC12278_00300) - 290141..290509 (+) 369 WP_018031088.1 DUF1033 family protein -
  DQL21_RS01575 (NCTC12278_00301) - 290748..291344 (+) 597 WP_018031089.1 PepSY domain-containing protein -
  DQL21_RS01580 (NCTC12278_00302) - 291488..292180 (+) 693 WP_018031090.1 response regulator transcription factor -
  DQL21_RS01585 (NCTC12278_00303) - 292143..293492 (+) 1350 WP_018031091.1 cell wall metabolism sensor histidine kinase WalK -
  DQL21_RS01590 (NCTC12278_00304) comYA 293545..294486 (+) 942 WP_018031092.1 competence type IV pilus ATPase ComGA Machinery gene
  DQL21_RS01595 (NCTC12278_00305) comYB 294383..295456 (+) 1074 WP_269458426.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQL21_RS01600 (NCTC12278_00306) comYC 295453..295767 (+) 315 WP_018031094.1 competence type IV pilus major pilin ComGC Machinery gene
  DQL21_RS01605 (NCTC12278_00307) comYD 295754..296167 (+) 414 WP_018031095.1 competence type IV pilus minor pilin ComGD Machinery gene
  DQL21_RS01610 (NCTC12278_00308) comGE 296157..296432 (+) 276 WP_018031096.1 competence type IV pilus minor pilin ComGE -
  DQL21_RS01615 (NCTC12278_00309) comYF 296398..296853 (+) 456 WP_040804182.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQL21_RS01620 (NCTC12278_00310) comGG 296831..297226 (+) 396 WP_018031098.1 competence type IV pilus minor pilin ComGG -
  DQL21_RS01625 (NCTC12278_00311) comYH 297276..298232 (+) 957 WP_018031099.1 class I SAM-dependent methyltransferase Machinery gene
  DQL21_RS01630 (NCTC12278_00312) - 298290..299483 (+) 1194 WP_018031100.1 acetate kinase -
  DQL21_RS01635 (NCTC12278_00313) - 299619..299816 (+) 198 WP_018031101.1 helix-turn-helix transcriptional regulator -
  DQL21_RS01640 (NCTC12278_00314) - 299877..300326 (+) 450 WP_018031102.1 hypothetical protein -

Sequence

Protein


Download         Length: 357 a.a.        Molecular weight: 40953.81 Da        Isoelectric Point: 9.5664

>NTDB_id=1137572 DQL21_RS01595 WP_269458426.1 294383..295456(+) (comYB) [Streptococcus ferus strain NCTC12278]
MKTIAQNNGIRRLINYMQQDICLRKTAKPKKLTTKSQQKVIQLFHNLLSSGFHLTEVVAFLDKSQLLPKIHVEAMSQGLL
QGQNLSEIMNELGFSADVVTQLALAEIHGNTESSLGKIEDYLTKVLAVKKKLFEVATYPIILLVFLVLIMLGLKNYLLPQ
LEEGNWATQIIGHFPTLFWLLSLLLVLTVALLFFFGKRLEPLRLMTICSRLPFFGVYVRLYLTAYYAREWGNLIGQGIEM
MQIVRLMQEQKSRRFAALGRDMEAALLSGQEFHQKISHYPFFLKELGLMIEYGQVKAKLGSELIFYAEEIWERFFSSIQK
AIQLIQPLVFIFVAIVIVLIYVAMLLPIYQNMEVPLT

Nucleotide


Download         Length: 1074 bp        

>NTDB_id=1137572 DQL21_RS01595 WP_269458426.1 294383..295456(+) (comYB) [Streptococcus ferus strain NCTC12278]
ATGAAAACCATAGCCCAGAACAATGGAATCAGGCGCTTGATCAATTATATGCAGCAGGACATCTGTCTGAGGAAGACTGC
CAAACCGAAAAAATTAACGACTAAGTCACAGCAAAAGGTTATCCAGCTTTTTCATAATCTTTTAAGTAGTGGGTTCCACC
TAACGGAGGTGGTTGCCTTTTTAGATAAGAGTCAGCTTTTGCCCAAGATCCATGTTGAAGCGATGAGTCAAGGGCTCCTA
CAGGGGCAAAATCTATCGGAGATTATGAATGAACTTGGCTTCTCAGCTGATGTGGTGACCCAGTTAGCCTTGGCAGAAAT
TCATGGGAATACAGAAAGTAGTTTGGGAAAAATCGAAGACTACTTAACCAAGGTACTGGCTGTAAAAAAGAAGTTGTTTG
AAGTGGCAACCTATCCGATTATCTTGCTTGTTTTCTTGGTCTTGATTATGCTGGGGCTAAAAAACTATTTGCTGCCACAA
CTGGAGGAAGGTAACTGGGCAACTCAGATCATCGGTCATTTTCCGACATTGTTTTGGTTGCTGTCTTTACTGCTAGTTTT
AACTGTGGCTCTCTTATTCTTTTTTGGAAAAAGGCTTGAACCCCTTCGGTTGATGACCATTTGCAGCCGACTGCCTTTTT
TCGGGGTCTATGTTAGGCTCTATCTGACGGCGTACTATGCGCGTGAATGGGGAAATTTAATTGGACAAGGGATTGAAATG
ATGCAAATCGTTCGCTTGATGCAGGAACAAAAATCAAGGCGCTTTGCTGCCCTTGGGCGGGACATGGAAGCTGCACTGTT
GTCTGGTCAAGAATTCCACCAGAAGATCTCGCATTACCCTTTTTTTCTAAAAGAGTTAGGCCTGATGATTGAATACGGGC
AGGTCAAGGCTAAGCTTGGCAGCGAGCTGATTTTTTATGCTGAGGAAATTTGGGAACGGTTCTTTTCCAGCATTCAGAAA
GCCATCCAGCTGATTCAGCCTCTGGTTTTTATTTTTGTTGCCATCGTTATTGTTCTAATTTATGTCGCTATGCTATTACC
CATTTATCAAAATATGGAGGTTCCTTTAACATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(227-347)

Type II secretion system (T2SS), protein F (T2SSF)

(41-159)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

65.015

96.078

0.625
  comYB Streptococcus mutans UA159

65.015

96.078

0.625
  comYB Streptococcus gordonii str. Challis substr. CH1

57.849

96.359

0.557
  comGB/cglB Streptococcus mitis NCTC 12261

58.716

91.597

0.538
  comGB/cglB Streptococcus mitis SK321

57.492

91.597

0.527
  comGB/cglB Streptococcus pneumoniae Rx1

57.187

91.597

0.524
  comGB/cglB Streptococcus pneumoniae D39

57.187

91.597

0.524
  comGB/cglB Streptococcus pneumoniae R6

57.187

91.597

0.524
  comGB/cglB Streptococcus pneumoniae TIGR4

57.187

91.597

0.524
  comGB Lactococcus lactis subsp. cremoris KW2

54.006

94.398

0.51

Multiple sequence alignment