Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   DQL21_RS01590 Genome accession   NZ_LS483343
Coordinates   293545..294486 (+) Length   313 a.a.
NCBI ID   WP_018031092.1    Uniprot ID   -
Organism   Streptococcus ferus strain NCTC12278     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 288545..299486
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL21_RS01570 (NCTC12278_00300) - 290141..290509 (+) 369 WP_018031088.1 DUF1033 family protein -
  DQL21_RS01575 (NCTC12278_00301) - 290748..291344 (+) 597 WP_018031089.1 PepSY domain-containing protein -
  DQL21_RS01580 (NCTC12278_00302) - 291488..292180 (+) 693 WP_018031090.1 response regulator transcription factor -
  DQL21_RS01585 (NCTC12278_00303) - 292143..293492 (+) 1350 WP_018031091.1 cell wall metabolism sensor histidine kinase WalK -
  DQL21_RS01590 (NCTC12278_00304) comYA 293545..294486 (+) 942 WP_018031092.1 competence type IV pilus ATPase ComGA Machinery gene
  DQL21_RS01595 (NCTC12278_00305) comYB 294383..295456 (+) 1074 WP_269458426.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQL21_RS01600 (NCTC12278_00306) comYC 295453..295767 (+) 315 WP_018031094.1 competence type IV pilus major pilin ComGC Machinery gene
  DQL21_RS01605 (NCTC12278_00307) comYD 295754..296167 (+) 414 WP_018031095.1 competence type IV pilus minor pilin ComGD Machinery gene
  DQL21_RS01610 (NCTC12278_00308) comGE 296157..296432 (+) 276 WP_018031096.1 competence type IV pilus minor pilin ComGE -
  DQL21_RS01615 (NCTC12278_00309) comYF 296398..296853 (+) 456 WP_040804182.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQL21_RS01620 (NCTC12278_00310) comGG 296831..297226 (+) 396 WP_018031098.1 competence type IV pilus minor pilin ComGG -
  DQL21_RS01625 (NCTC12278_00311) comYH 297276..298232 (+) 957 WP_018031099.1 class I SAM-dependent methyltransferase Machinery gene
  DQL21_RS01630 (NCTC12278_00312) - 298290..299483 (+) 1194 WP_018031100.1 acetate kinase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35396.27 Da        Isoelectric Point: 6.0534

>NTDB_id=1137571 DQL21_RS01590 WP_018031092.1 293545..294486(+) (comYA) [Streptococcus ferus strain NCTC12278]
MVQDLGKKIIAQAVEEKAQDIYMIPRAEAYELYMRIGDERRFIDVFGHDRMASLISHFKFVAGMNVGEKRRSQLGSCDYE
YADGESISLRLSSVGDYRSYESLVIRLLFKGRHDLHFWFNGMETILKEIRGRGLYLFSGPVGSGKTSLMYQLVKEKFSSK
QVISIEDPVEIKEDHILQLQLNESIGMTYDSLIKLSLRHRPDVLMIGEIRDSQTARAVIRASLTGATVFSTIHAKSISGV
YARLLELGVSRDELDNSLRGIAYQRLIGGGGLIDFAGKDYENHSPEQWNQALDQLYAAGHLSEEDCQTEKIND

Nucleotide


Download         Length: 942 bp        

>NTDB_id=1137571 DQL21_RS01590 WP_018031092.1 293545..294486(+) (comYA) [Streptococcus ferus strain NCTC12278]
ATGGTTCAGGATTTAGGGAAAAAAATAATTGCTCAGGCCGTTGAGGAAAAGGCTCAGGATATTTATATGATTCCGCGGGC
AGAAGCCTATGAGCTTTACATGAGGATCGGTGATGAAAGGAGATTTATTGATGTTTTTGGGCATGATCGCATGGCTAGTC
TTATTAGTCACTTTAAATTTGTCGCAGGAATGAATGTTGGTGAGAAGAGACGAAGTCAGCTGGGCTCTTGTGACTACGAG
TATGCCGATGGAGAGAGTATCTCTCTGCGGCTGTCTAGTGTCGGTGATTACCGGTCTTATGAAAGTCTGGTGATCCGTCT
GCTTTTTAAAGGACGTCATGACCTTCACTTTTGGTTTAATGGGATGGAAACAATTCTGAAAGAAATCAGAGGACGAGGCT
TGTATCTTTTTTCGGGACCTGTTGGGTCTGGAAAAACGAGCTTGATGTACCAGCTGGTAAAGGAAAAATTTTCTTCCAAG
CAGGTGATTAGTATTGAGGATCCTGTGGAAATTAAGGAGGATCACATTTTGCAGCTGCAGCTTAATGAAAGCATTGGTAT
GACTTATGACAGTCTTATTAAGCTGTCTTTGCGGCATCGCCCAGATGTTTTAATGATTGGTGAAATTCGAGATTCACAAA
CCGCACGCGCGGTCATCAGAGCCAGTCTAACGGGGGCGACTGTTTTTTCGACTATTCATGCCAAAAGCATTTCGGGAGTT
TATGCGCGTCTGTTGGAACTCGGTGTCAGTCGGGATGAATTAGATAACAGTCTAAGAGGAATTGCTTACCAACGTTTAAT
AGGGGGAGGAGGGCTTATTGATTTTGCCGGAAAAGACTATGAAAACCATAGCCCAGAACAATGGAATCAGGCGCTTGATC
AATTATATGCAGCAGGACATCTGTCTGAGGAAGACTGCCAAACCGAAAAAATTAACGACTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

76.358

100

0.764
  comYA Streptococcus mutans UA140

76.038

100

0.76
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

68.269

99.681

0.681
  comYA Streptococcus gordonii str. Challis substr. CH1

67.412

100

0.674
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

65.705

99.681

0.655
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

64.744

99.681

0.645
  comGA/cglA/cilD Streptococcus pneumoniae D39

64.744

99.681

0.645
  comGA/cglA/cilD Streptococcus pneumoniae R6

64.744

99.681

0.645
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

64.744

99.681

0.645
  comGA Lactococcus lactis subsp. cremoris KW2

52.716

100

0.527
  comGA Latilactobacillus sakei subsp. sakei 23K

39.929

90.415

0.361

Multiple sequence alignment