Detailed information    

insolico Bioinformatically predicted

Overview


Name   comYC   Type   Machinery gene
Locus tag   GPW69_RS00755 Genome accession   NZ_LR738724
Coordinates   115930..116211 (+) Length   93 a.a.
NCBI ID   WP_074391328.1    Uniprot ID   -
Organism   Streptococcus suis isolate 9401240     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 110930..121211
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPW69_RS00735 - 112591..112965 (+) 375 WP_024385120.1 DUF1033 family protein -
  GPW69_RS00740 - 112993..113943 (-) 951 WP_074391326.1 S66 peptidase family protein -
  GPW69_RS00745 comYA 114029..114979 (+) 951 WP_074391327.1 competence type IV pilus ATPase ComGA Machinery gene
  GPW69_RS00750 comYB 114891..115928 (+) 1038 WP_269472402.1 competence type IV pilus assembly protein ComGB Machinery gene
  GPW69_RS00755 comYC 115930..116211 (+) 282 WP_074391328.1 competence type IV pilus major pilin ComGC Machinery gene
  GPW69_RS00760 comGD 116192..116599 (+) 408 WP_074391329.1 competence type IV pilus minor pilin ComGD -
  GPW69_RS00765 comYE 116571..116864 (+) 294 WP_024401507.1 competence type IV pilus minor pilin ComGE Machinery gene
  GPW69_RS00770 comGF/cglF 116851..117285 (+) 435 WP_044762030.1 competence type IV pilus minor pilin ComGF Machinery gene
  GPW69_RS00775 comGG 117263..117676 (+) 414 WP_074391330.1 competence type IV pilus minor pilin ComGG -
  GPW69_RS00780 comYH 117726..118679 (+) 954 WP_024414316.1 class I SAM-dependent methyltransferase Machinery gene
  GPW69_RS00785 - 118729..119916 (+) 1188 WP_044680792.1 acetate kinase -
  GPW69_RS00790 - 120233..120784 (+) 552 WP_074391332.1 folate family ECF transporter S component -

Sequence


Protein


Download         Length: 93 a.a.        Molecular weight: 10474.48 Da        Isoelectric Point: 8.3596

>NTDB_id=1129582 GPW69_RS00755 WP_074391328.1 115930..116211(+) (comYC) [Streptococcus suis isolate 9401240]
MKKLIEMKVKGFTLVEMLVVLGIISLLLLLFVPNLSKQKDAIQKKGDAAVVKVVESQMELYELEYDKEATVEDLQKAGYI
TPKQAEQYATAKK

Nucleotide


Download         Length: 282 bp        

>NTDB_id=1129582 GPW69_RS00755 WP_074391328.1 115930..116211(+) (comYC) [Streptococcus suis isolate 9401240]
ATGAAAAAATTAATTGAAATGAAGGTAAAAGGGTTCACTCTGGTGGAAATGTTAGTCGTTTTGGGAATTATCAGCCTGCT
CTTGCTCCTCTTTGTGCCAAATTTGAGCAAGCAGAAGGATGCTATTCAGAAGAAGGGGGATGCTGCGGTTGTCAAAGTAG
TGGAGAGTCAGATGGAGCTCTATGAATTGGAATATGATAAGGAAGCAACGGTGGAGGACTTGCAAAAGGCTGGTTATATT
ACGCCAAAACAAGCGGAGCAGTATGCTACGGCGAAAAAATAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYC Streptococcus suis isolate S10

90.323

100

0.903

  comGC/cglC Streptococcus pneumoniae Rx1

61.957

98.925

0.613

  comGC/cglC Streptococcus pneumoniae D39

61.957

98.925

0.613

  comGC/cglC Streptococcus pneumoniae R6

61.957

98.925

0.613

  comGC/cglC Streptococcus pneumoniae TIGR4

61.957

98.925

0.613

  comGC/cglC Streptococcus mitis NCTC 12261

61.957

98.925

0.613

  comGC/cglC Streptococcus mitis SK321

61.957

98.925

0.613

  comYC Streptococcus gordonii str. Challis substr. CH1

62.921

95.699

0.602

  comYC Streptococcus mutans UA140

60.227

94.624

0.57

  comYC Streptococcus mutans UA159

60.227

94.624

0.57

  comGC Lactococcus lactis subsp. cremoris KW2

57.955

94.624

0.548

  comGC Staphylococcus aureus MW2

48.718

83.871

0.409

  comGC Staphylococcus aureus N315

48.718

83.871

0.409

  comGC Bacillus subtilis subsp. subtilis str. 168

48

80.645

0.387


Multiple sequence alignment