Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   GPW69_RS00750 Genome accession   NZ_LR738724
Coordinates   114891..115928 (+) Length   345 a.a.
NCBI ID   WP_269472402.1    Uniprot ID   -
Organism   Streptococcus suis isolate 9401240     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 109891..120928
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPW69_RS00735 - 112591..112965 (+) 375 WP_024385120.1 DUF1033 family protein -
  GPW69_RS00740 - 112993..113943 (-) 951 WP_074391326.1 S66 peptidase family protein -
  GPW69_RS00745 comYA 114029..114979 (+) 951 WP_074391327.1 competence type IV pilus ATPase ComGA Machinery gene
  GPW69_RS00750 comYB 114891..115928 (+) 1038 WP_269472402.1 competence type IV pilus assembly protein ComGB Machinery gene
  GPW69_RS00755 comYC 115930..116211 (+) 282 WP_074391328.1 competence type IV pilus major pilin ComGC Machinery gene
  GPW69_RS00760 comGD 116192..116599 (+) 408 WP_074391329.1 competence type IV pilus minor pilin ComGD -
  GPW69_RS00765 comYE 116571..116864 (+) 294 WP_024401507.1 competence type IV pilus minor pilin ComGE Machinery gene
  GPW69_RS00770 comGF/cglF 116851..117285 (+) 435 WP_044762030.1 competence type IV pilus minor pilin ComGF Machinery gene
  GPW69_RS00775 comGG 117263..117676 (+) 414 WP_074391330.1 competence type IV pilus minor pilin ComGG -
  GPW69_RS00780 comYH 117726..118679 (+) 954 WP_024414316.1 class I SAM-dependent methyltransferase Machinery gene
  GPW69_RS00785 - 118729..119916 (+) 1188 WP_044680792.1 acetate kinase -
  GPW69_RS00790 - 120233..120784 (+) 552 WP_074391332.1 folate family ECF transporter S component -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 39014.03 Da        Isoelectric Point: 9.3363

>NTDB_id=1129581 GPW69_RS00750 WP_269472402.1 114891..115928(+) (comYB) [Streptococcus suis isolate 9401240]
MRKLIAFLQQDISVFGRQKQKKLPLDRQRKVIELFNNLFASGFHLGEIVDFLKRSQLLADPYTQVLSDGLLAGKPFSSLL
ADLRFSDAVVTQVALAEVHGNTSLSLSHIQSYLKNVSKVRKKLIEVATYPIILLGFLLLIMLGLKNYLLPQLEEGNAATM
LINHLPTIFLSLCGLSLVAVLAGLVWFRKTNKIRVFSCLAALPFFGKLIQTYLTAYYAREWGSLIGQGLDLPQIVGLMQE
QQSQLFREIGQDLEQSLSNGQSFHEHIKTYAFFKRELSLIVEYGQVKSKLGGELTVYAAECWEDFFSRVNRAMQLIQPLV
FLFVALMVVLIYAAMLLPIYQNMEL

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=1129581 GPW69_RS00750 WP_269472402.1 114891..115928(+) (comYB) [Streptococcus suis isolate 9401240]
ATGCGCAAATTGATCGCCTTTTTGCAGCAGGACATATCAGTCTTCGGCAGGCAGAAACAGAAAAAATTGCCTTTGGATCG
CCAGCGTAAGGTCATTGAGCTTTTCAATAATCTTTTTGCTAGTGGTTTTCATTTGGGGGAAATTGTTGATTTCCTCAAAC
GCAGTCAGCTTCTGGCAGATCCCTATACCCAGGTCTTGTCAGACGGGCTGTTAGCAGGCAAACCCTTTTCAAGTTTGCTG
GCAGATTTGCGGTTTTCAGATGCGGTGGTCACGCAGGTGGCACTGGCAGAAGTTCATGGCAATACCAGCCTGAGTTTGAG
CCATATCCAGTCCTATTTGAAAAATGTCAGCAAGGTTCGTAAAAAACTGATTGAGGTGGCGACCTATCCGATTATCTTAC
TAGGTTTTCTGCTCTTGATTATGCTGGGTTTGAAAAATTACCTTCTGCCCCAGTTGGAGGAAGGCAATGCAGCGACTATG
CTAATTAACCATTTGCCGACCATCTTTTTATCCCTCTGTGGACTTAGTTTGGTGGCGGTCTTGGCTGGTCTTGTTTGGTT
TCGCAAAACCAACAAAATCAGGGTCTTTTCCTGCTTAGCAGCTCTGCCATTTTTCGGAAAACTCATCCAAACCTATCTGA
CGGCCTATTACGCCAGGGAGTGGGGGAGTTTGATTGGGCAAGGCTTGGACCTGCCGCAGATTGTGGGTTTGATGCAGGAG
CAGCAATCGCAGCTCTTTCGAGAGATTGGACAGGACCTGGAGCAGTCGCTTTCCAATGGTCAGAGTTTTCACGAACACAT
TAAGACCTATGCCTTTTTTAAGCGGGAGCTGAGTTTGATTGTCGAGTATGGTCAGGTCAAGTCCAAGTTGGGTGGCGAGT
TGACAGTCTATGCAGCCGAGTGCTGGGAGGACTTTTTCTCTCGGGTCAATAGAGCCATGCAGCTGATTCAACCGCTGGTC
TTTCTCTTTGTGGCCTTAATGGTCGTTCTCATCTACGCAGCCATGTTGCTGCCGATTTATCAAAATATGGAGTTGTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(33-150)

Type II secretion system (T2SS), protein F (T2SSF)

(218-338)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

63.45

99.13

0.629
  comGB/cglB Streptococcus mitis NCTC 12261

60.896

97.101

0.591
  comYB Streptococcus mutans UA140

59.184

99.42

0.588
  comYB Streptococcus mutans UA159

59.184

99.42

0.588
  comGB/cglB Streptococcus mitis SK321

60.597

97.101

0.588
  comGB/cglB Streptococcus pneumoniae Rx1

60

97.101

0.583
  comGB/cglB Streptococcus pneumoniae D39

60

97.101

0.583
  comGB/cglB Streptococcus pneumoniae R6

60

97.101

0.583
  comGB/cglB Streptococcus pneumoniae TIGR4

60

97.101

0.583
  comGB Lactococcus lactis subsp. cremoris KW2

50.742

97.681

0.496

Multiple sequence alignment