Detailed information NTG1129580

Bioinformatically predicted

Overview

• Name: comYA
• Type: Machinery gene
• Locus tag: GPW69_RS00745
• Genome accession: NZ_LR738724
• Coordinates: 114029..114979 (+)
• Length: 316 a.a.
• NCBI ID: WP_074391327.1
• Uniprot ID: -
• Organism: Streptococcus suis isolate 9401240
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 109029..119979

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GPW69_RS00735	-	112591..112965 (+)	375	WP_024385120.1	DUF1033 family protein	-
GPW69_RS00740	-	112993..113943 (-)	951	WP_074391326.1	S66 peptidase family protein	-
GPW69_RS00745	comYA	114029..114979 (+)	951	WP_074391327.1	competence type IV pilus ATPase ComGA	Machinery gene
GPW69_RS00750	comYB	114891..115928 (+)	1038	WP_269472402.1	competence type IV pilus assembly protein ComGB	Machinery gene
GPW69_RS00755	comYC	115930..116211 (+)	282	WP_074391328.1	competence type IV pilus major pilin ComGC	Machinery gene
GPW69_RS00760	comGD	116192..116599 (+)	408	WP_074391329.1	competence type IV pilus minor pilin ComGD	-
GPW69_RS00765	comYE	116571..116864 (+)	294	WP_024401507.1	competence type IV pilus minor pilin ComGE	Machinery gene
GPW69_RS00770	comGF/cglF	116851..117285 (+)	435	WP_044762030.1	competence type IV pilus minor pilin ComGF	Machinery gene
GPW69_RS00775	comGG	117263..117676 (+)	414	WP_074391330.1	competence type IV pilus minor pilin ComGG	-
GPW69_RS00780	comYH	117726..118679 (+)	954	WP_024414316.1	class I SAM-dependent methyltransferase	Machinery gene
GPW69_RS00785	-	118729..119916 (+)	1188	WP_044680792.1	acetate kinase	-

Sequence

Protein

• Length: 316 a.a.
• Molecular weight: 35399.21 Da
• Isoelectric Point: 5.6938

>NTDB_id=1129580 GPW69_RS00745 WP_074391327.1 114029..114979(+) (comYA) [Streptococcus suis isolate 9401240]
MIQEKARKMIEEAVADRVSDIYLVPRGQGYQVYHRIMDEREFVQDVAEEEVTAIISHFKFLAGLNVGEKRRSQQGSCDYD
YGSGEISLRLSTVGDYRGKESLVIRLLYDNDKELKFWFEAAERLAEEIKGRGLYLFSGPVGSGKTTLMYHLARLKFPDKQ
ILTIEDPVEIKQEDMLQLQLNEAIGATYDNLIKLSLRHRPDLLIIGEIRDAETARAVIRASLTGATVFSTVHARSISGVY
ARMLELGVSPEELNNALQGIAYQRLIGGGGVVDFAKGNYQNHSADQWNAQIDRLFAAGHISLRQAETEKIAFGSPA

Nucleotide

• Length: 951 bp

>NTDB_id=1129580 GPW69_RS00745 WP_074391327.1 114029..114979(+) (comYA) [Streptococcus suis isolate 9401240]
ATGATTCAAGAAAAAGCAAGAAAGATGATTGAAGAGGCAGTGGCAGATAGGGTCAGTGATATTTATCTGGTTCCTCGTGG
TCAGGGCTATCAAGTCTATCATCGCATCATGGATGAACGGGAGTTTGTGCAAGACGTGGCTGAAGAGGAAGTGACAGCCA
TTATCAGCCATTTCAAGTTTTTAGCAGGTTTAAATGTTGGTGAAAAACGCCGTAGCCAGCAGGGTTCCTGTGACTATGAT
TATGGTAGCGGAGAGATTTCACTTCGCTTATCAACTGTCGGTGATTATCGTGGTAAGGAAAGTTTGGTTATCCGCCTGCT
CTATGACAATGACAAGGAACTCAAGTTCTGGTTTGAGGCGGCCGAGCGACTTGCAGAAGAAATCAAGGGACGAGGGCTCT
ACCTTTTTTCGGGTCCAGTCGGCTCTGGTAAGACCACACTTATGTACCATCTTGCCAGGCTGAAATTCCCAGACAAGCAG
ATTTTGACCATCGAGGATCCTGTCGAAATCAAACAGGAGGACATGCTGCAACTCCAGCTCAATGAAGCCATCGGAGCCAC
CTACGACAATCTGATCAAACTGTCCCTCCGCCATCGACCAGACTTGCTCATCATCGGAGAGATTCGGGATGCGGAAACCG
CTCGAGCAGTCATTCGAGCCAGTCTGACGGGAGCTACCGTTTTCTCAACAGTTCATGCAAGGTCTATTTCAGGAGTCTAT
GCCCGTATGTTAGAACTAGGTGTCAGCCCTGAGGAGTTAAATAATGCCCTTCAAGGCATTGCCTATCAACGTTTGATTGG
GGGAGGAGGTGTAGTAGATTTTGCAAAGGGAAATTACCAAAACCATTCCGCAGACCAGTGGAATGCGCAAATTGATCGCC
TTTTTGCAGCAGGACATATCAGTCTTCGGCAGGCAGAAACAGAAAAAATTGCCTTTGGATCGCCAGCGTAA

Domains

Predicted by InterproScan.

• Type II/IV secretion system protein (T2SSE) (8-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYA	Streptococcus gordonii str. Challis substr. CH1	68.71	98.101	0.674
comYA	Streptococcus mutans UA159	67.524	98.418	0.665
comYA	Streptococcus mutans UA140	67.524	98.418	0.665
comGA/cglA/cilD	Streptococcus pneumoniae Rx1	65.064	98.734	0.642
comGA/cglA/cilD	Streptococcus mitis NCTC 12261	65.064	98.734	0.642
comGA/cglA/cilD	Streptococcus pneumoniae D39	65.064	98.734	0.642
comGA/cglA/cilD	Streptococcus pneumoniae R6	65.064	98.734	0.642
comGA/cglA/cilD	Streptococcus pneumoniae TIGR4	65.064	98.734	0.642
comGA/cglA	Streptococcus sobrinus strain NIDR 6715-7	64.839	98.101	0.636
comGA	Lactococcus lactis subsp. cremoris KW2	53.628	100	0.538
comGA	Latilactobacillus sakei subsp. sakei 23K	41.155	87.658	0.361