Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   FGL23_RS09550 Genome accession   NZ_LR594049
Coordinates   1987334..1988272 (-) Length   312 a.a.
NCBI ID   WP_061603434.1    Uniprot ID   -
Organism   Streptococcus gordonii strain NCTC10231     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1982334..1993272
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL23_RS09510 (NCTC10231_01902) - 1982340..1983533 (-) 1194 WP_061603429.1 acetate kinase -
  FGL23_RS09515 (NCTC10231_01903) comYH 1983583..1984536 (-) 954 WP_061603430.1 class I SAM-dependent methyltransferase Machinery gene
  FGL23_RS09520 (NCTC10231_01904) comGG 1984567..1984998 (-) 432 WP_231092517.1 competence type IV pilus minor pilin ComGG -
  FGL23_RS09525 (NCTC10231_01905) comGF/cglF 1984979..1985416 (-) 438 WP_061603431.1 competence type IV pilus minor pilin ComGF Machinery gene
  FGL23_RS09530 (NCTC10231_01906) comGE/cglE 1985400..1985693 (-) 294 WP_061597051.1 competence type IV pilus minor pilin ComGE Machinery gene
  FGL23_RS09535 (NCTC10231_01907) comYD 1985665..1986093 (-) 429 WP_081106361.1 competence type IV pilus minor pilin ComGD Machinery gene
  FGL23_RS09540 (NCTC10231_01908) comYC 1986053..1986370 (-) 318 WP_012130940.1 competence type IV pilus major pilin ComGC Machinery gene
  FGL23_RS09545 (NCTC10231_01909) comYB 1986367..1987401 (-) 1035 WP_061603433.1 competence type IV pilus assembly protein ComGB Machinery gene
  FGL23_RS09550 (NCTC10231_01910) comYA 1987334..1988272 (-) 939 WP_061603434.1 competence type IV pilus ATPase ComGA Machinery gene
  FGL23_RS09555 (NCTC10231_01911) - 1988374..1988742 (-) 369 WP_061600994.1 DUF1033 family protein -
  FGL23_RS09560 (NCTC10231_01912) rpoC 1988994..1992641 (-) 3648 WP_080889720.1 DNA-directed RNA polymerase subunit beta' -

Sequence

Protein


Download         Length: 312 a.a.        Molecular weight: 35791.68 Da        Isoelectric Point: 5.0503

>NTDB_id=1128001 FGL23_RS09550 WP_061603434.1 1987334..1988272(-) (comYA) [Streptococcus gordonii strain NCTC10231]
MVQKIAQAIVRQAKEESAQDIYFVPKDDCYELYMRIGDERRFIQTYDFDQLAAVISHFKFLAGMNVGEKRRSQLGSCDYR
YDDKETSIRLSTVGDYRGYESLVIRLLHDEETELKFWFTHFPEFREKFKDRGLYLFSGPVGSGKTTLMHQLAQLKFKGQQ
VMSIEDPVEIKQEDMLQLQLNETIGLTYESLIKLSLRHRPDLLIIGEIRDSETARAVVRASLTGATVFSTIHAKSIPGVY
ERLLELGVSEEELKIVLQGICYQRLIGGGGVIDFASDDYQEHEPTVWNQQIDQLLAAGHINPEQAEAEKIRN

Nucleotide


Download         Length: 939 bp        

>NTDB_id=1128001 FGL23_RS09550 WP_061603434.1 1987334..1988272(-) (comYA) [Streptococcus gordonii strain NCTC10231]
ATGGTTCAAAAAATTGCCCAGGCGATTGTCCGGCAAGCTAAGGAAGAGTCTGCTCAGGATATTTATTTTGTACCCAAGGA
TGATTGCTATGAACTTTATATGCGGATTGGCGATGAGCGACGCTTCATACAGACTTATGATTTTGACCAATTAGCTGCTG
TGATTAGTCATTTTAAATTTCTAGCAGGGATGAATGTGGGCGAAAAACGTCGCAGTCAGCTGGGGTCCTGTGATTATCGC
TATGATGATAAGGAAACATCAATTCGTCTGTCAACTGTAGGTGATTATCGTGGTTATGAGAGTTTGGTTATTCGACTCTT
GCACGATGAAGAGACAGAATTGAAGTTTTGGTTTACTCATTTTCCTGAGTTTAGAGAGAAGTTTAAGGATCGAGGACTGT
ATCTTTTTTCGGGACCAGTAGGGAGTGGCAAGACCACTCTCATGCATCAATTAGCTCAGCTAAAATTTAAGGGTCAGCAA
GTTATGTCCATTGAGGATCCTGTTGAAATCAAGCAAGAGGATATGCTTCAGCTACAGCTGAATGAAACGATTGGTTTGAC
CTATGAAAGTCTGATTAAACTTTCCCTGCGTCACCGTCCGGACTTGCTCATCATTGGAGAAATTCGGGATAGTGAAACCG
CTAGAGCAGTAGTTCGAGCTAGCTTGACGGGAGCTACAGTTTTTTCAACGATTCACGCTAAGAGCATTCCTGGTGTTTAC
GAACGCTTATTGGAATTGGGTGTTAGCGAGGAGGAGTTGAAAATTGTTTTACAGGGTATTTGCTATCAACGCTTGATTGG
GGGAGGAGGTGTGATAGACTTTGCCAGCGACGACTACCAAGAACACGAGCCGACCGTCTGGAATCAGCAGATTGATCAAC
TTCTTGCAGCAGGACATATCAATCCTGAGCAAGCAGAAGCAGAAAAAATTAGGAACTAG

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

98.718

100

0.987
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

78.387

99.359

0.779
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

78.065

99.359

0.776
  comGA/cglA/cilD Streptococcus pneumoniae D39

78.065

99.359

0.776
  comGA/cglA/cilD Streptococcus pneumoniae R6

78.065

99.359

0.776
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

78.065

99.359

0.776
  comYA Streptococcus mutans UA159

67.412

100

0.676
  comYA Streptococcus mutans UA140

67.412

100

0.676
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

65.385

100

0.654
  comGA Lactococcus lactis subsp. cremoris KW2

54.808

100

0.548

Multiple sequence alignment