Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   FGL23_RS09545 Genome accession   NZ_LR594049
Coordinates   1986367..1987401 (-) Length   344 a.a.
NCBI ID   WP_061603433.1    Uniprot ID   -
Organism   Streptococcus gordonii strain NCTC10231     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1981367..1992401
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL23_RS09505 (NCTC10231_01901) - 1981627..1982292 (-) 666 WP_061603428.1 CPBP family intramembrane glutamic endopeptidase -
  FGL23_RS09510 (NCTC10231_01902) - 1982340..1983533 (-) 1194 WP_061603429.1 acetate kinase -
  FGL23_RS09515 (NCTC10231_01903) comYH 1983583..1984536 (-) 954 WP_061603430.1 class I SAM-dependent methyltransferase Machinery gene
  FGL23_RS09520 (NCTC10231_01904) comGG 1984567..1984998 (-) 432 WP_231092517.1 competence type IV pilus minor pilin ComGG -
  FGL23_RS09525 (NCTC10231_01905) comGF/cglF 1984979..1985416 (-) 438 WP_061603431.1 competence type IV pilus minor pilin ComGF Machinery gene
  FGL23_RS09530 (NCTC10231_01906) comGE/cglE 1985400..1985693 (-) 294 WP_061597051.1 competence type IV pilus minor pilin ComGE Machinery gene
  FGL23_RS09535 (NCTC10231_01907) comYD 1985665..1986093 (-) 429 WP_081106361.1 competence type IV pilus minor pilin ComGD Machinery gene
  FGL23_RS09540 (NCTC10231_01908) comYC 1986053..1986370 (-) 318 WP_012130940.1 competence type IV pilus major pilin ComGC Machinery gene
  FGL23_RS09545 (NCTC10231_01909) comYB 1986367..1987401 (-) 1035 WP_061603433.1 competence type IV pilus assembly protein ComGB Machinery gene
  FGL23_RS09550 (NCTC10231_01910) comYA 1987334..1988272 (-) 939 WP_061603434.1 competence type IV pilus ATPase ComGA Machinery gene
  FGL23_RS09555 (NCTC10231_01911) - 1988374..1988742 (-) 369 WP_061600994.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 344 a.a.        Molecular weight: 39184.17 Da        Isoelectric Point: 8.8904

>NTDB_id=1128000 FGL23_RS09545 WP_061603433.1 1986367..1987401(-) (comYB) [Streptococcus gordonii strain NCTC10231]
MINFLQQDISILSKQKQKKLGTSKQKQVIELFNNLFSSGFHLAETVDFLGRSALLEKNYVQQMRHGLANGQAFSEIMASL
GFSDAVVTQLSLAELHGNLSLALLKIEEYLDNLAKVKKKLIEVATYPMMLLGFLVLIMMGLRNYLLPQLSSQNFATQLIG
HLPTIFLLTVLIFLGLTGAIYLVFKGQKRIPVYSFLARLPFVGSFVRIYLTAYYAREWGNMIGQGLELSQIFQIMQEQRS
VLFQEIGQDLGQALQNGQEFSDKITSYPFFKKELSLIIEYGEVKSKLGSELEIYALKTWEEFFGRDNRTMNLIQPLVFVF
VALMIVLLYAAMLLPLYQNMEVHL

Nucleotide


Download         Length: 1035 bp        

>NTDB_id=1128000 FGL23_RS09545 WP_061603433.1 1986367..1987401(-) (comYB) [Streptococcus gordonii strain NCTC10231]
TTGATCAACTTCTTGCAGCAGGACATATCAATCCTGAGCAAGCAGAAGCAGAAAAAATTAGGAACTAGCAAGCAAAAGCA
GGTCATTGAACTGTTTAATAATTTATTCTCTAGCGGTTTTCACTTGGCTGAGACTGTAGATTTTTTAGGACGAAGCGCTC
TTTTGGAGAAGAACTATGTCCAGCAAATGCGTCATGGTCTAGCCAATGGACAAGCATTTTCAGAGATTATGGCTAGTCTA
GGTTTTTCTGATGCGGTAGTAACCCAGCTGTCATTGGCTGAGTTACATGGGAATTTATCGCTTGCATTGCTAAAAATAGA
GGAGTATCTGGATAATCTTGCGAAGGTAAAAAAGAAGTTAATTGAAGTAGCAACCTATCCCATGATGCTTCTTGGCTTTT
TGGTATTGATTATGATGGGATTGAGAAATTACCTTTTACCCCAACTCAGCAGTCAAAATTTTGCCACTCAACTCATTGGC
CATTTACCGACTATTTTTCTACTAACTGTCTTAATTTTTCTTGGATTAACAGGAGCGATTTATCTGGTATTCAAAGGTCA
GAAACGGATTCCTGTATACTCTTTCTTGGCCCGCTTGCCTTTTGTTGGATCTTTTGTAAGGATTTACCTAACTGCCTATT
ATGCGCGTGAATGGGGCAATATGATTGGGCAAGGTTTGGAACTCAGTCAGATTTTCCAGATTATGCAAGAGCAACGCTCG
GTTTTATTTCAGGAAATTGGCCAGGATTTGGGTCAAGCCTTGCAGAATGGTCAAGAATTTTCAGATAAAATAACTTCTTA
CCCTTTTTTCAAAAAAGAATTGTCTCTAATCATCGAATATGGGGAAGTCAAATCCAAGCTGGGAAGTGAACTAGAAATTT
ATGCCCTTAAGACTTGGGAAGAATTTTTTGGTAGGGACAATCGGACCATGAATCTGATTCAGCCCCTAGTCTTTGTCTTT
GTAGCCTTGATGATTGTCTTACTGTATGCGGCAATGCTATTGCCCCTTTATCAAAATATGGAGGTTCATCTATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(215-335)

Type II secretion system (T2SS), protein F (T2SSF)

(30-147)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

97.965

100

0.98
  comGB/cglB Streptococcus mitis NCTC 12261

71.848

99.128

0.712
  comGB/cglB Streptococcus mitis SK321

72.024

97.674

0.703
  comGB/cglB Streptococcus pneumoniae TIGR4

70.833

97.674

0.692
  comGB/cglB Streptococcus pneumoniae R6

70.833

97.674

0.692
  comGB/cglB Streptococcus pneumoniae Rx1

70.833

97.674

0.692
  comGB/cglB Streptococcus pneumoniae D39

70.833

97.674

0.692
  comYB Streptococcus mutans UA140

60.35

99.709

0.602
  comYB Streptococcus mutans UA159

60.058

99.709

0.599
  comGB Lactococcus lactis subsp. cremoris KW2

51.632

97.965

0.506

Multiple sequence alignment