Detailed information NTG1127996

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: FGL23_RS09525
• Genome accession: NZ_LR594049
• Coordinates: 1984979..1985416 (-)
• Length: 145 a.a.
• NCBI ID: WP_061603431.1
• Uniprot ID: -
• Organism: Streptococcus gordonii strain NCTC10231
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1979979..1990416

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGL23_RS09500 (NCTC10231_01900)	folP	1980584..1981549 (-)	966	WP_061603427.1	dihydropteroate synthase	-
FGL23_RS09505 (NCTC10231_01901)	-	1981627..1982292 (-)	666	WP_061603428.1	CPBP family intramembrane glutamic endopeptidase	-
FGL23_RS09510 (NCTC10231_01902)	-	1982340..1983533 (-)	1194	WP_061603429.1	acetate kinase	-
FGL23_RS09515 (NCTC10231_01903)	comYH	1983583..1984536 (-)	954	WP_061603430.1	class I SAM-dependent methyltransferase	Machinery gene
FGL23_RS09520 (NCTC10231_01904)	comGG	1984567..1984998 (-)	432	WP_231092517.1	competence type IV pilus minor pilin ComGG	-
FGL23_RS09525 (NCTC10231_01905)	comGF/cglF	1984979..1985416 (-)	438	WP_061603431.1	competence type IV pilus minor pilin ComGF	Machinery gene
FGL23_RS09530 (NCTC10231_01906)	comGE/cglE	1985400..1985693 (-)	294	WP_061597051.1	competence type IV pilus minor pilin ComGE	Machinery gene
FGL23_RS09535 (NCTC10231_01907)	comYD	1985665..1986093 (-)	429	WP_081106361.1	competence type IV pilus minor pilin ComGD	Machinery gene
FGL23_RS09540 (NCTC10231_01908)	comYC	1986053..1986370 (-)	318	WP_012130940.1	competence type IV pilus major pilin ComGC	Machinery gene
FGL23_RS09545 (NCTC10231_01909)	comYB	1986367..1987401 (-)	1035	WP_061603433.1	competence type IV pilus assembly protein ComGB	Machinery gene
FGL23_RS09550 (NCTC10231_01910)	comYA	1987334..1988272 (-)	939	WP_061603434.1	competence type IV pilus ATPase ComGA	Machinery gene
FGL23_RS09555 (NCTC10231_01911)	-	1988374..1988742 (-)	369	WP_061600994.1	DUF1033 family protein	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16583.05 Da
• Isoelectric Point: 6.7333

>NTDB_id=1127996 FGL23_RS09525 WP_061603431.1 1984979..1985416(-) (comGF/cglF) [Streptococcus gordonii strain NCTC10231]
MLKKGKVAAFTLLEALVALLVISGGLLVFQAMTKLLASEIQYQEQTKAKEWLLFADQLDAELSRSHFEKVEQNKLYVKQD
GKSIAFGKSRSDDFRKTDGNGRGYQPMIYGLEAAQINKEGQIVHLLLQFRDGLEREYIYRVEEEH

Nucleotide

• Length: 438 bp

>NTDB_id=1127996 FGL23_RS09525 WP_061603431.1 1984979..1985416(-) (comGF/cglF) [Streptococcus gordonii strain NCTC10231]
ATGTTGAAAAAAGGTAAAGTAGCAGCCTTCACCCTGCTGGAAGCCTTAGTGGCCCTCTTGGTCATCAGTGGTGGCCTCTT
GGTTTTCCAGGCAATGACCAAGCTTCTAGCCAGTGAGATTCAGTATCAAGAGCAAACTAAGGCCAAGGAGTGGCTCTTGT
TTGCGGACCAGTTAGATGCAGAATTATCCCGGAGCCATTTTGAAAAAGTCGAGCAAAATAAGCTTTATGTCAAACAAGAT
GGCAAGTCGATTGCATTTGGTAAGTCTAGAAGCGATGATTTTAGAAAAACAGATGGGAATGGCCGTGGTTATCAGCCCAT
GATTTATGGACTAGAAGCTGCTCAAATAAATAAAGAAGGTCAGATAGTTCATTTGCTTCTGCAGTTTAGAGATGGCCTAG
AAAGAGAGTACATCTATCGTGTTGAAGAAGAACATTAG

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (38-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus mitis NCTC 12261	66.667	97.241	0.648
comGF/cglF	Streptococcus pneumoniae Rx1	66.197	97.931	0.648
comGF/cglF	Streptococcus pneumoniae D39	66.197	97.931	0.648
comGF/cglF	Streptococcus pneumoniae R6	66.197	97.931	0.648
comGF/cglF	Streptococcus pneumoniae TIGR4	66.197	97.931	0.648
comGF/cglF	Streptococcus mitis SK321	65.248	97.241	0.634
comYF	Streptococcus mutans UA140	46.479	97.931	0.455
comYF	Streptococcus mutans UA159	45.775	97.931	0.448
comGF	Lactococcus lactis subsp. cremoris KW2	42.857	96.552	0.414