Detailed information
Bioinformatically predicted
Overview
| Name | pilU | Type | Machinery gene |
| Locus tag | FGL10_RS01120 | Genome accession | NZ_LR590477 |
| Coordinates | 191038..192168 (+) | Length | 376 a.a. |
| NCBI ID | WP_036469395.1 | Uniprot ID | - |
| Organism | Neisseria lactamica strain NCTC10617 | ||
| Function | assembly of type IV pilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 176716..236338 | 191038..192168 | within | 0 |
Gene organization within MGE regions
Location: 176716..236338
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FGL10_RS01040 (NCTC10617_00181) | rfbD | 176924..177787 (-) | 864 | WP_003708034.1 | dTDP-4-dehydrorhamnose reductase | - |
| FGL10_RS01045 (NCTC10617_00182) | - | 177993..178856 (+) | 864 | WP_003708035.1 | phosphoribosylaminoimidazolesuccinocarboxamide synthase | - |
| FGL10_RS01055 (NCTC10617_00183) | pnp | 179090..181213 (+) | 2124 | WP_003708039.1 | polyribonucleotide nucleotidyltransferase | - |
| FGL10_RS01060 (NCTC10617_00184) | - | 181286..181954 (-) | 669 | WP_003708040.1 | sulfite exporter TauE/SafE family protein | - |
| FGL10_RS01065 (NCTC10617_00185) | - | 181951..182265 (-) | 315 | WP_003708042.1 | hypothetical protein | - |
| FGL10_RS01070 (NCTC10617_00186) | - | 182456..182743 (-) | 288 | WP_003708044.1 | barstar family protein | - |
| FGL10_RS01080 (NCTC10617_00187) | dapF | 182858..183709 (+) | 852 | WP_003708046.1 | diaminopimelate epimerase | - |
| FGL10_RS01085 (NCTC10617_00188) | - | 183706..184311 (+) | 606 | WP_003708048.1 | hypothetical protein | - |
| FGL10_RS01090 (NCTC10617_00190) | cysK | 184507..185439 (+) | 933 | WP_036469372.1 | cysteine synthase A | - |
| FGL10_RS01100 (NCTC10617_00191) | - | 185756..186655 (+) | 900 | WP_003708052.1 | DMT family transporter | - |
| FGL10_RS11920 | - | 186701..186850 (+) | 150 | WP_003708054.1 | hypothetical protein | - |
| FGL10_RS01105 (NCTC10617_00192) | lepB | 187069..188088 (-) | 1020 | WP_003708057.1 | signal peptidase I | - |
| FGL10_RS01110 (NCTC10617_00193) | lepA | 188233..190026 (-) | 1794 | WP_003708059.1 | translation elongation factor 4 | - |
| FGL10_RS01115 (NCTC10617_00194) | - | 190171..190872 (-) | 702 | WP_003708062.1 | 5'-methylthioadenosine/adenosylhomocysteine nucleosidase | - |
| FGL10_RS01120 (NCTC10617_00195) | pilU | 191038..192168 (+) | 1131 | WP_036469395.1 | PilT/PilU family type 4a pilus ATPase | Machinery gene |
| FGL10_RS01125 (NCTC10617_00196) | - | 192203..193180 (+) | 978 | WP_003708066.1 | DNA polymerase III subunit delta' | - |
| FGL10_RS01130 (NCTC10617_00197) | - | 193184..193534 (+) | 351 | WP_003708068.1 | PilZ domain-containing protein | - |
| FGL10_RS01135 (NCTC10617_00198) | - | 193539..194318 (+) | 780 | WP_003708070.1 | TatD family hydrolase | - |
| FGL10_RS01140 (NCTC10617_00199) | - | 194519..194977 (+) | 459 | WP_003708074.1 | RNA-guided endonuclease InsQ/TnpB family protein | - |
| FGL10_RS01150 | - | 195292..195450 (-) | 159 | Protein_205 | transposase | - |
| FGL10_RS01155 (NCTC10617_00200) | - | 195606..202532 (+) | 6927 | WP_036474987.1 | hemagglutinin repeat-containing protein | - |
| FGL10_RS01160 | - | 202513..202827 (+) | 315 | WP_003712152.1 | hypothetical protein | - |
| FGL10_RS01165 (NCTC10617_00201) | - | 202991..203449 (+) | 459 | WP_003711517.1 | protein-lysine palmitoyltransferase | - |
| FGL10_RS12890 | - | 203504..205291 (+) | 1788 | Protein_209 | ShlB/FhaC/HecB family hemolysin secretion/activation protein | - |
| FGL10_RS01180 (NCTC10617_00204) | - | 205628..206917 (-) | 1290 | WP_036470677.1 | type II toxin-antitoxin system HipA family toxin | - |
| FGL10_RS01185 (NCTC10617_00205) | - | 206929..207945 (-) | 1017 | WP_003711434.1 | IS1595 family transposase | - |
| FGL10_RS01195 (NCTC10617_00206) | - | 208451..208801 (+) | 351 | WP_003711431.1 | helix-turn-helix domain-containing protein | - |
| FGL10_RS01200 | - | 208705..209583 (+) | 879 | WP_080718803.1 | IS3 family transposase | - |
| FGL10_RS01205 (NCTC10617_00208) | - | 209599..210045 (+) | 447 | Protein_214 | transposase | - |
| FGL10_RS12980 (NCTC10617_00209) | - | 210234..210356 (+) | 123 | WP_003710898.1 | hypothetical protein | - |
| FGL10_RS12985 | - | 210375..210782 (+) | 408 | WP_415087386.1 | CRISPR-associated endonuclease Cas3'' | - |
| FGL10_RS12990 (NCTC10617_00210) | - | 210703..211037 (+) | 335 | Protein_217 | CRISPR-associated helicase/endonuclease Cas3 | - |
| FGL10_RS01215 (NCTC10617_00211) | - | 211086..214646 (+) | 3561 | WP_036474990.1 | SIR2 family NAD-dependent protein deacylase | - |
| FGL10_RS01220 (NCTC10617_00212) | cas5c | 214732..215406 (+) | 675 | WP_036470299.1 | type I-C CRISPR-associated protein Cas5c | - |
| FGL10_RS01225 (NCTC10617_00213) | - | 215403..215898 (+) | 496 | Protein_220 | type I-C CRISPR-associated protein Cas8c/Csd1 | - |
| FGL10_RS01230 (NCTC10617_00214) | - | 216030..216470 (-) | 441 | WP_036470302.1 | hypothetical protein | - |
| FGL10_RS01235 (NCTC10617_00215) | - | 216470..217561 (-) | 1092 | WP_050774467.1 | IS1595 family transposase | - |
| FGL10_RS01240 (NCTC10617_00216) | - | 217656..217886 (+) | 231 | WP_003710914.1 | DUF6471 domain-containing protein | - |
| FGL10_RS01245 (NCTC10617_00217) | - | 217911..219188 (+) | 1278 | WP_003710916.1 | type II toxin-antitoxin system HipA family toxin | - |
| FGL10_RS01250 (NCTC10617_00218) | - | 219583..220863 (+) | 1281 | WP_003710918.1 | ATP-binding protein | - |
| FGL10_RS12415 (NCTC10617_00219) | - | 221071..221505 (+) | 435 | WP_003710920.1 | RNA-guided endonuclease InsQ/TnpB family protein | - |
| FGL10_RS12420 (NCTC10617_00220) | - | 221506..222207 (+) | 702 | WP_003710923.1 | RNA-guided endonuclease InsQ/TnpB family protein | - |
| FGL10_RS01265 (NCTC10617_00221) | grxD | 222704..223015 (+) | 312 | WP_002241342.1 | Grx4 family monothiol glutaredoxin | - |
| FGL10_RS01275 (NCTC10617_00222) | upp | 223121..223747 (+) | 627 | WP_002242442.1 | uracil phosphoribosyltransferase | - |
| FGL10_RS01280 (NCTC10617_00223) | - | 223770..224087 (+) | 318 | WP_003710925.1 | DUF2322 family protein | - |
| FGL10_RS01285 (NCTC10617_00224) | - | 224224..224646 (+) | 423 | WP_003710927.1 | protein Gly1ORF1 | - |
| FGL10_RS01290 (NCTC10617_00225) | - | 224664..225444 (+) | 781 | Protein_232 | uroporphyrinogen-III synthase | - |
| FGL10_RS01295 (NCTC10617_00226) | - | 225431..226792 (+) | 1362 | WP_036474993.1 | uroporphyrinogen-III C-methyltransferase | - |
| FGL10_RS01300 (NCTC10617_00227) | - | 226789..228012 (+) | 1224 | WP_003710936.1 | heme biosynthesis protein HemY | - |
| FGL10_RS01305 (NCTC10617_00228) | - | 228045..228485 (+) | 441 | WP_003710937.1 | hypothetical protein | - |
| FGL10_RS01310 (NCTC10617_00229) | hemE | 228639..229703 (+) | 1065 | WP_003710939.1 | uroporphyrinogen decarboxylase | - |
| FGL10_RS01315 (NCTC10617_00230) | radA | 229893..231272 (+) | 1380 | WP_118778960.1 | DNA repair protein RadA | Machinery gene |
| FGL10_RS01325 (NCTC10617_00231) | - | 231548..232027 (-) | 480 | WP_036470308.1 | DUF302 domain-containing protein | - |
| FGL10_RS01330 (NCTC10617_00232) | - | 232279..232638 (-) | 360 | WP_003710949.1 | rhodanese-like domain-containing protein | - |
| FGL10_RS01335 (NCTC10617_00233) | recB | 232677..236291 (-) | 3615 | WP_003710950.1 | exodeoxyribonuclease V subunit beta | Machinery gene |
Sequence
Protein
Download Length: 376 a.a. Molecular weight: 42055.23 Da Isoelectric Point: 6.7231
>NTDB_id=1126916 FGL10_RS01120 WP_036469395.1 191038..192168(+) (pilU) [Neisseria lactamica strain NCTC10617]
MFAGENMTAKEELFAWLRHMNKNKGSDLFVTTHFPPAMKLDGKITRITDTPLTAEKCMEIAFSIMSAKQAEEFSSTNECN
FAISLPDTSRFRVNAMIQRGATALVFRAITSKIPKFESLNLPPVLKDVALKKRGLVIFVGGTGSGKSTSLASLIDYRNEN
SFGHIITIEDPIEFVHEHKNCIITQREVGVDTENWMAALKNTLRQAPDVILIGEIRDRETMDYAIAFAETGHLCMATLHA
NSTNQALDRIINFFPEERREQLLTDLSLNLQAFISQRLVPRDGGKGRVAAVEVLLNSPLISELIHNGNIHEIKEVMKKST
TLGMQTFDQHLYQLYEKGDISLQDALKNADSAHDLRLAVQLRSRRAQSSGPDLELL
MFAGENMTAKEELFAWLRHMNKNKGSDLFVTTHFPPAMKLDGKITRITDTPLTAEKCMEIAFSIMSAKQAEEFSSTNECN
FAISLPDTSRFRVNAMIQRGATALVFRAITSKIPKFESLNLPPVLKDVALKKRGLVIFVGGTGSGKSTSLASLIDYRNEN
SFGHIITIEDPIEFVHEHKNCIITQREVGVDTENWMAALKNTLRQAPDVILIGEIRDRETMDYAIAFAETGHLCMATLHA
NSTNQALDRIINFFPEERREQLLTDLSLNLQAFISQRLVPRDGGKGRVAAVEVLLNSPLISELIHNGNIHEIKEVMKKST
TLGMQTFDQHLYQLYEKGDISLQDALKNADSAHDLRLAVQLRSRRAQSSGPDLELL
Nucleotide
Download Length: 1131 bp
>NTDB_id=1126916 FGL10_RS01120 WP_036469395.1 191038..192168(+) (pilU) [Neisseria lactamica strain NCTC10617]
ATGTTTGCCGGTGAAAATATGACTGCAAAGGAAGAACTGTTCGCCTGGCTGCGCCATATGAACAAAAACAAAGGTTCCGA
CCTGTTTGTGACGACCCATTTCCCGCCCGCGATGAAGCTGGACGGCAAAATTACCCGCATCACGGATACGCCGCTGACGG
CGGAAAAATGTATGGAAATCGCCTTTTCGATTATGAGTGCGAAGCAGGCGGAAGAATTTTCATCGACCAACGAGTGCAAC
TTCGCCATCAGCCTGCCGGACACCAGCCGCTTCCGCGTCAATGCGATGATACAGCGCGGCGCAACGGCGTTGGTATTCCG
CGCGATTACCAGCAAGATTCCCAAGTTTGAAAGCCTGAACCTGCCGCCTGTCTTGAAGGATGTCGCGCTGAAAAAACGCG
GGCTGGTTATTTTTGTCGGCGGCACCGGCTCGGGCAAATCGACTTCGCTTGCCTCGCTTATCGATTACCGCAATGAAAAT
TCGTTCGGACACATCATCACCATCGAAGACCCGATCGAATTTGTCCACGAACACAAAAACTGCATCATCACCCAGCGCGA
GGTTGGCGTGGATACGGAAAACTGGATGGCGGCGTTGAAAAACACGCTGCGGCAGGCACCCGATGTCATCCTTATCGGCG
AAATCCGCGACCGCGAAACAATGGACTACGCCATTGCCTTTGCCGAAACGGGGCATTTGTGTATGGCGACGCTGCACGCC
AACAGCACCAATCAGGCACTCGACCGCATCATCAACTTTTTCCCCGAGGAGCGGCGCGAACAATTGCTGACGGATTTGTC
GCTCAACCTTCAGGCGTTTATTTCGCAACGCCTCGTTCCGCGAGACGGCGGCAAGGGCAGGGTGGCGGCAGTCGAGGTGC
TGCTCAATTCGCCCCTAATTTCGGAGTTGATTCACAACGGCAACATCCATGAAATCAAAGAAGTGATGAAAAAATCCACT
ACCCTGGGTATGCAGACCTTCGACCAACACCTTTACCAATTGTATGAAAAAGGCGATATTTCCTTGCAGGATGCCTTGAA
AAATGCCGATTCGGCGCATGATTTGCGTTTGGCTGTTCAGTTGAGAAGCCGCCGCGCGCAAAGTTCCGGACCGGATTTGG
AATTGCTCTGA
ATGTTTGCCGGTGAAAATATGACTGCAAAGGAAGAACTGTTCGCCTGGCTGCGCCATATGAACAAAAACAAAGGTTCCGA
CCTGTTTGTGACGACCCATTTCCCGCCCGCGATGAAGCTGGACGGCAAAATTACCCGCATCACGGATACGCCGCTGACGG
CGGAAAAATGTATGGAAATCGCCTTTTCGATTATGAGTGCGAAGCAGGCGGAAGAATTTTCATCGACCAACGAGTGCAAC
TTCGCCATCAGCCTGCCGGACACCAGCCGCTTCCGCGTCAATGCGATGATACAGCGCGGCGCAACGGCGTTGGTATTCCG
CGCGATTACCAGCAAGATTCCCAAGTTTGAAAGCCTGAACCTGCCGCCTGTCTTGAAGGATGTCGCGCTGAAAAAACGCG
GGCTGGTTATTTTTGTCGGCGGCACCGGCTCGGGCAAATCGACTTCGCTTGCCTCGCTTATCGATTACCGCAATGAAAAT
TCGTTCGGACACATCATCACCATCGAAGACCCGATCGAATTTGTCCACGAACACAAAAACTGCATCATCACCCAGCGCGA
GGTTGGCGTGGATACGGAAAACTGGATGGCGGCGTTGAAAAACACGCTGCGGCAGGCACCCGATGTCATCCTTATCGGCG
AAATCCGCGACCGCGAAACAATGGACTACGCCATTGCCTTTGCCGAAACGGGGCATTTGTGTATGGCGACGCTGCACGCC
AACAGCACCAATCAGGCACTCGACCGCATCATCAACTTTTTCCCCGAGGAGCGGCGCGAACAATTGCTGACGGATTTGTC
GCTCAACCTTCAGGCGTTTATTTCGCAACGCCTCGTTCCGCGAGACGGCGGCAAGGGCAGGGTGGCGGCAGTCGAGGTGC
TGCTCAATTCGCCCCTAATTTCGGAGTTGATTCACAACGGCAACATCCATGAAATCAAAGAAGTGATGAAAAAATCCACT
ACCCTGGGTATGCAGACCTTCGACCAACACCTTTACCAATTGTATGAAAAAGGCGATATTTCCTTGCAGGATGCCTTGAA
AAATGCCGATTCGGCGCATGATTTGCGTTTGGCTGTTCAGTTGAGAAGCCGCCGCGCGCAAAGTTCCGGACCGGATTTGG
AATTGCTCTGA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| pilU | Pseudomonas stutzeri DSM 10701 |
59.943 |
93.617 |
0.561 |
| pilU | Acinetobacter baylyi ADP1 |
58.017 |
91.223 |
0.529 |
| pilU | Vibrio cholerae strain A1552 |
54.039 |
95.479 |
0.516 |
| pilT | Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539 |
43.059 |
93.883 |
0.404 |
| pilT | Legionella pneumophila strain Lp02 |
43.827 |
86.17 |
0.378 |
| pilT | Legionella pneumophila strain ERS1305867 |
43.827 |
86.17 |
0.378 |
| pilT | Acinetobacter baylyi ADP1 |
42.727 |
87.766 |
0.375 |
| pilT | Pseudomonas aeruginosa PAK |
42.683 |
87.234 |
0.372 |
| pilT | Acinetobacter nosocomialis M2 |
42.901 |
86.17 |
0.37 |
| pilT | Acinetobacter baumannii D1279779 |
42.901 |
86.17 |
0.37 |
| pilT | Acinetobacter baumannii strain A118 |
42.901 |
86.17 |
0.37 |
| pilT | Neisseria meningitidis 8013 |
40.896 |
89.096 |
0.364 |
| pilT | Pseudomonas stutzeri DSM 10701 |
41.768 |
87.234 |
0.364 |